Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response (Q36293358)

13 August 2017

Tyrosine 370 phosphorylation of ATM positively regulates DNA damage response (English)

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13 August 2017

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16

Mien-Chie Hung

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13 August 2017

14

K Kian Ang

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13 August 2017

10

Shih-Shin Chang

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13 August 2017

7

Chien-Chia Cheng

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13 August 2017

1

Hong-Jen Lee

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13 August 2017

6

Ying-Nai Wang

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13 August 2017

Li Lan

2

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13 August 2017

Guang Peng

3

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13 August 2017

Wei-Chao Chang

4

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13 August 2017

Ming-Chuan Hsu

5

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13 August 2017

Leizhen Wei

8

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13 August 2017

Satoshi Nakajima

9

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13 August 2017

Hsin-Wei Liao

11

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13 August 2017

Chung-Hsuan Chen

12

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13 August 2017

Martin Lavin

13

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13 August 2017

Shiaw-Yih Lin

15

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13 August 2017

20 January 2015

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13 August 2017

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25

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13 August 2017

225-236

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13 August 2017

2

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https://scigraph.springernature.com/pub.10.1038/cr.2015.8

13 August 2017

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cites work

KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling

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Targeting the EGFR/PCNA signaling suppresses tumor growth of triple-negative breast cancer cells with cell-penetrating PCNA peptides

30 September 2017

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Nuclear EGFR suppresses ribonuclease activity of polynucleotide phosphorylase through DNAPK-mediated phosphorylation at serine 776.

30 September 2017

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Sequential application of anticancer drugs enhances cell death by rewiring apoptotic signaling networks.

30 September 2017

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IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression

30 September 2017

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More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

30 September 2017

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Gefitinib induces epidermal growth factor receptor dimers which alters the interaction characteristics with ¹²⁵I-EGF

30 September 2017

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Prediction of synergistic antitumour effect of gefitinib and radiation in vitro

30 September 2017

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Targeting tyrosine phosphorylation of PCNA inhibits prostate cancer growth.

30 September 2017

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Autophosphorylation and ATM activation: additional sites add to the complexity

30 September 2017

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Gefitinib radiosensitizes non-small cell lung cancer cells through inhibition of ataxia telangiectasia mutated

30 September 2017

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Nuclear trafficking of the epidermal growth factor receptor family membrane proteins

30 September 2017

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Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response

30 September 2017

1 reference

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Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors

30 September 2017

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The combined status of ATM and p53 link tumor development with therapeutic response

30 September 2017

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BRIT1/MCPH1 links chromatin remodelling to DNA damage response.

30 September 2017

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Molecular therapy in head and neck oncology

30 September 2017

1 reference

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Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK.

30 September 2017

1 reference

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Dancing on damaged chromatin: functions of ATM and the RAD50/MRE11/NBS1 complex in cellular responses to DNA damage

30 September 2017

1 reference

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Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

30 September 2017

1 reference

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The DNA damage response: ten years after

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

ATM activation and DNA damage response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

KAP1, a novel substrate for PIKK family members, colocalizes with numerous damage response factors at DNA lesions

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Tyrosine phosphorylation controls PCNA function through protein stability

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Involvement of novel autophosphorylation sites in ATM activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival.

30 September 2017

1 reference

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Accumulation of Werner protein at DNA double-strand breaks in human cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Control of epidermal growth factor receptor endocytosis by receptor dimerization, rather than receptor kinase activation

30 September 2017

1 reference

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Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Nuclear interaction of EGFR and STAT3 in the activation of the iNOS/NO pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

In situ analysis of repair processes for oxidative DNA damage in mammalian cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Ataxia-telangiectasia, an evolving phenotype

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Requirement of the MRN complex for ATM activation by DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Nuclear localization of EGF receptor and its potential new role as a transcription factor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Untangling the ErbB signalling network

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

The many substrates and functions of ATM

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Caffeine abolishes the mammalian G(2)/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

The controlling role of ATM in homologous recombinational repair of DNA damage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

ATM associates with and phosphorylates p53: mapping the region of interaction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Gefitinib radiosensitizes stem-like glioma cells: inhibition of epidermal growth factor receptor-Akt-DNA-PK signaling, accompanied by inhibition of DNA double-strand break repair.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Expression of phosphorylated histone H2AX in cultured cell lines following exposure to X-rays.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4650576

Initial steps of ferulic acid polymerization by lignin peroxidase

22 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCR.2015.8

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCR.2015.8

Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo

21 January 2018

1 reference

12 December 2020

Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation

1 reference

12 December 2020

Histone H2AX Phosphorylation as a Predictor of Radiosensitivity and Target for Radiotherapy

1 reference

12 December 2020

Functional nuclear epidermal growth factor receptors in human choriocarcinoma JEG-3 cells and normal human placenta

1 reference

12 December 2020

Physical interaction between epidermal growth factor receptor and DNA-dependent protein kinase in mammalian cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/CR.2015.8

1 reference

release_fq5sbcfojzd37bwyphsmker2yq

13 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fq5sbcfojzd37bwyphsmker2yq

24 November 2022

mapped directly with Wikidata item

1 reference

13 August 2017

1 reference