Fibrils colocalize caspase-3 with procaspase-3 to foster maturation (Q36286189)

13 August 2017

Fibrils colocalize caspase-3 with procaspase-3 to foster maturation (English)

1 reference

13 August 2017

Dennis W Wolan

2

0 references

Nicholas J Agard

series ordinal

3

object named as

Nicholas J Agard

1 reference

13 August 2017

Julie A Zorn

1

1 reference

13 August 2017

James A Wells

series ordinal

4

1 reference

13 August 2017

language of work or name

English

0 references

publication date

7 August 2012

1 reference

13 August 2017

15

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

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13 August 2017

287

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13 August 2017

40

1 reference

13 August 2017

33781-33795

1 reference

describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3460474/fullTextXML

inferred from PubMed Central ID database lookup

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Preparing synthetic Aβ in different aggregation states

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Activation of specific apoptotic caspases with an engineered small-molecule-activated protease

30 September 2017

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Allosteric regulation of protease activity by small molecules.

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Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation

30 September 2017

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30 September 2017

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Prion-like mechanisms in neurodegenerative diseases

30 September 2017

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30 September 2017

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Structural and kinetic determinants of protease substrates

30 September 2017

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PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibition

30 September 2017

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APP binds DR6 to trigger axon pruning and neuron death via distinct caspases

30 September 2017

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Caspases in apoptosis and beyond

30 September 2017

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Small Molecule-Induced Allosteric Activation of the Vibrio cholerae RTX Cysteine Protease Domain

30 September 2017

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Global mapping of the topography and magnitude of proteolytic events in apoptosis

30 September 2017

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Global sequencing of proteolytic cleavage sites in apoptosis by specific labeling of protein N termini

30 September 2017

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30 September 2017

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The CASBAH: a searchable database of caspase substrates

30 September 2017

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Targeting proteases: successes, failures and future prospects

30 September 2017

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Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy

30 September 2017

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A common allosteric site and mechanism in caspases

30 September 2017

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The apoptosome activates caspase-9 by dimerization

30 September 2017

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Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine

30 September 2017

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Caspase-7 is directly activated by the approximately 700-kDa apoptosome complex and is released as a stable XIAP-caspase-7 approximately 200-kDa complex

30 September 2017

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Pulse proteolysis: A simple method for quantitative determination of protein stability and ligand binding

30 September 2017

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Components of the cell death machine and drug sensitivity of the National Cancer Institute Cell Line Panel.

30 September 2017

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Discovery of an allosteric site in the caspases

30 September 2017

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Intermediate filaments control the intracellular distribution of caspases during apoptosis.

30 September 2017

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Mutations in the Procaspase-3 Dimer Interface Affect the Activity of the Zymogen

30 September 2017

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Interdimer processing mechanism of procaspase-8 activation.

30 September 2017

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Insights into the regulatory mechanism for caspase-8 activation

30 September 2017

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Structure and zymogen activation of caspases

30 September 2017

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DEDD regulates degradation of intermediate filaments during apoptosis

30 September 2017

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Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

30 September 2017

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Dimer formation drives the activation of the cell death protease caspase 9

30 September 2017

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Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

30 September 2017

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Intracellular antibody-caspase-mediated cell killing: an approach for application in cancer therapy.

30 September 2017

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Caspases and neurodegeneration: on the cutting edge of new therapeutic approaches.

30 September 2017

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Caspases - controlling intracellular signals by protease zymogen activation

30 September 2017

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Catalytic properties of the caspases

30 September 2017

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Caspase activation: the induced-proximity model

30 September 2017

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

30 September 2017

1 reference

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Death-effector filaments: novel cytoplasmic structures that recruit caspases and trigger apoptosis

30 September 2017

1 reference

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Molecular mechanisms for the conversion of zymogens to active proteolytic enzymes

30 September 2017

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Synthetic activation of caspases: artificial death switches

30 September 2017

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An induced proximity model for caspase-8 activation.

30 September 2017

1 reference

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Biochemical characteristics of caspases-3, -6, -7, and -8

30 September 2017

1 reference

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Zymogens of Proteolytic Enzymes

30 September 2017

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The single-chain form of tissue-type plasminogen activator has catalytic activity: studies with a mutant enzyme that lacks the cleavage site

30 September 2017

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Role of proteolytic enzymes in biological regulation (a review)

30 September 2017

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Mechanisms of zymogen activation

30 September 2017

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Amyloid-β forms fibrils by nucleated conformational conversion of oligomers

30 September 2017

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Stoichiometry and physical chemistry of promiscuous aggregate-based inhibitors

29 June 2018

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Expression, purification, and characterization of caspases

29 June 2018

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Prefibrillar amyloid protein aggregates share common features of cytotoxicity.

29 June 2018

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Conversion of procaspase-3 to an autoactivating caspase by fusion to the caspase-2 prodomain

29 June 2018

1 reference

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Autoproteolytic activation of pro-caspases by oligomerization.

29 June 2018

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Converting tissue-type plasminogen activator into a zymogen.

29 June 2018

1 reference

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Probing structure-function relationships of tissue-type plasminogen activator by oligonucleotide-mediated site-specific mutagenesis

29 June 2018

1 reference

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The relation of the -amino group of trypsin to enzyme function and zymogen activation.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460474

Caspase-8 isoform 6 promotes death effector filament formation independent of microtubules.

29 June 2018

1 reference

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Intraneuronal amyloid β oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo.

22 September 2018

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Caspase assays: identifying caspase activity and substrates in vitro and in vivo.

22 September 2018

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Engineered hybrid dimers: tracking the activation pathway of caspase-7.

22 September 2018

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Identification of early intermediates of caspase activation using selective inhibitors and activity-based probes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460474

Kinetic comparison of procaspase-3 and caspase-3.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460474

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460474

Removal of the pro-domain does not affect the conformation of the procaspase-3 dimer.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460474

Kinetic analysis of a simplified scheme of autocatalytic zymogen activation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3460474

Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity

22 September 2018

1 reference

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In vitro stimulation of tissue-type plasminogen activator by Alzheimer amyloid β-peptide analogues

22 September 2018

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Inhibition of beta-amyloid fibrillization by directed evolution of a beta-sheet presenting miniature protein

22 September 2018

1 reference

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FLICE Induced Apoptosis in a Cell-free System

21 October 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.386128

Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser

21 January 2018

1 reference

12 December 2020

Tissue-type plasminogen activator is a multiligand cross-beta structure receptor

1 reference

12 December 2020

The Autoactivation of Trypsinogen

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12 December 2020

Catalysis by chymotrypsinogen. Demonstration of an acyl-zymogen intermediate

1 reference

12 December 2020

Probes of the mechanism of zymogen catalysis

1 reference

12 December 2020

Enzymatic activities of activated and zymogen forms of human Hageman factor (factor XII)

1 reference

12 December 2020

Functional role of proteolytic cleavage at arginine-275 of human tissue plasminogen activator as assessed by site-directed mutagenesis

1 reference

12 December 2020

Properties of the caspases

1 reference

12 December 2020

Extended substrate recognition in caspase-3 revealed by high resolution X-ray structure analysis

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12 December 2020

Quantitative determination of protein stability and ligand binding by pulse proteolysis

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12 December 2020

Identifiers

DOI

10.1074/JBC.M112.386128

1 reference

13 August 2017

1 reference

13 August 2017

1 reference