Interdimer processing mechanism of procaspase-8 activation. (Q39832029)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12912912%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

Interdimer processing mechanism of procaspase-8 activation (English)

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6 November 2019

4

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6 November 2019

Marcus E. Peter

5

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6 November 2019

author name string

David W Chang

1

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6 November 2019

Zheng Xing

2

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6 November 2019

Vanessa L Capacio

3

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6 November 2019

Xiaolu Yang

6

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6 November 2019

publication date

1 August 2003

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6 November 2019

language of work or name

0 references

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6 November 2019

volume

22

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6 November 2019

issue

16

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6 November 2019

page(s)

4132-4142

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

6 November 2019

cites work

1 reference

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Insights into the regulatory mechanism for caspase-8 activation

22 September 2017

1 reference

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A unified model for apical caspase activation

22 September 2017

1 reference

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Activation of procaspases by FK506 binding protein-mediated oligomerization

22 September 2017

1 reference

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Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

22 September 2017

1 reference

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The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis

22 September 2017

1 reference

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The Fas signaling pathway: more than a paradigm

22 September 2017

1 reference

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Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

22 September 2017

1 reference

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Molecular Ordering of the Initial Signaling Events of CD95

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Proteases for cell suicide: functions and regulation of caspases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Cell signaling by receptor tyrosine kinases

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

From bench to clinic with apoptosis-based therapeutic agents

22 September 2017

1 reference

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CD95's deadly mission in the immune system

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

The biochemistry of apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Caspase-8 specificity probed at subsite S(4): crystal structure of the caspase-8-Z-DEVD-cho complex

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Caspase structure, proteolytic substrates, and function during apoptotic cell death

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

The atomic-resolution structure of human caspase-8, a key activator of apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Caspase activation: the induced-proximity model

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

The role of c-FLIP in modulation of CD95-induced apoptosis

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Redesigning an FKBP–ligand interface to generate chemical dimerizers with novel specificity

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

22 September 2017

Caspases: Enemies Within

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Death Receptors: Signaling and Modulation

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

An induced proximity model for caspase-8 activation.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Essential Role of CED-4 Oligomerization in CED-3 Activation and Apoptosis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Membrane Oligomerization and Cleavage Activates the Caspase-8 (FLICE/MACHα1) Death Signal

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Autoproteolytic Activation of Pro-Caspases by Oligomerization

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Oligomerization is a general mechanism for the activation of apoptosis initiator and inflammatory procaspases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

Activation of initiator caspases through a stable dimeric intermediate

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=175803

20 August 2018

Identifiers

DOI

10.1093/EMBOJ/CDG414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12912912%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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6 November 2019

PubMed publication ID

12912912

1 reference