Molecular mechanisms of HIV-1 proviral latency (Q36278085)

13 August 2017

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title

Molecular mechanisms of HIV-1 proviral latency (English)

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13 August 2017

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Dwayne Bisgrove

1

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13 August 2017

Mary Lewinski

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2

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13 August 2017

Frederic Bushman

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3

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13 August 2017

Eric Verdin

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4

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13 August 2017

1 October 2005

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Expert Review of Anti-infective Therapy

13 August 2017

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13 August 2017

3

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13 August 2017

805-814

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13 August 2017

5

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Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase

13 August 2017

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Viral dynamics in human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Decay characteristics of HIV-1-infected compartments during combination therapy

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

In vivo fate of HIV-1-infected T cells: quantitative analysis of the transition to stable latency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

A compilation of cellular transcription factor interactions with the HIV-1 LTR promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Activation of the HIV-1 enhancer by the LEF-1 HMG protein on nucleosome-assembled DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Regulation of HIV-1 gene transcription: from lymphocytes to microglial cells

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Shaping the nuclear action of NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

DSIF and NELF interact with RNA polymerase II elongation complex and HIV-1 Tat stimulates P-TEFb-mediated phosphorylation of RNA polymerase II and DSIF during transcription elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

A novel CDK9-associated C-type cyclin interacts directly with HIV-1 Tat and mediates its high-affinity, loop-specific binding to TAR RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Dynamics of human immunodeficiency virus transcription: P-TEFb phosphorylates RD and dissociates negative effectors from the transactivation response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Spt5 cooperates with human immunodeficiency virus type 1 Tat by preventing premature RNA release at terminator sequences

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Domains in the SPT5 protein that modulate its transcriptional regulatory properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

CDK9 autophosphorylation regulates high-affinity binding of the human immunodeficiency virus type 1 tat-P-TEFb complex to TAR RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Induction of TAK (cyclin T1/P-TEFb) in purified resting CD4(+) T lymphocytes by combination of cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Electron microscopy of defined lengths of chromatin

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Chromatin Structure: A Repeating Unit of Histones and DNA

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

An octamer of histones in chromatin and free in solution

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

The language of covalent histone modifications

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Purified histone acetyltransferase complexes stimulate HIV-1 transcription from preassembled nucleosomal arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Stable co-occupancy of transcription factors and histones at the HIV-1 enhancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Recruitment of SWI/SNF to the human immunodeficiency virus type 1 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

HIV-1 tat transcriptional activity is regulated by acetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

SIRT1 regulates HIV transcription via Tat deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

A point mutation in the HIV-1 Tat responsive element is associated with postintegration latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

HIV reproducibly establishes a latent infection after acute infection of T cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Heterochromatin--many flavours, common themes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Resting CD4+ T cells from human immunodeficiency virus type 1 (HIV-1)-infected individuals carry integrated HIV-1 genomes within actively transcribed host genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

HIV-1 integration in the human genome favors active genes and local hotspots

21 January 2018

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https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Transcription start regions in the human genome are favored targets for MLV integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

The challenge of viral reservoirs in HIV-1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Interleukin-7 induces expression of latent human immunodeficiency virus type 1 with minimal effects on T-cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

A nonpromoting phorbol from the samoan medicinal plant Homalanthus nutans inhibits cell killing by HIV-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Effects of prostratin on T-cell activation and human immunodeficiency virus latency

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Prostratin: activation of latent HIV-1 expression suggests a potential inductive adjuvant therapy for HAART.

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-kappaB and inhibitors of deacetylases: potential perspectives for the development of therapeutic strategies

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Sexual Transmission and Propagation of SIV and HIV in Resting and Activated CD4+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

Hairpin RNAs and retrotransposon LTRs effect RNAi and chromatin-based gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2F14787210.3.5.805

21 January 2018

Identifiers

DOI

10.1586/14787210.3.5.805

1 reference

13 August 2017

1 reference