Don't lose heart--therapeutic value of apoptosis prevention in the treatment of cardiovascular disease. (Q36275682)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16202209%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

review article

1 reference

title

Don't lose heart--therapeutic value of apoptosis prevention in the treatment of cardiovascular disease (English)

1 reference

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7 January 2020

main subject

apoptotic process

0 references

cardiovascular disease

1 reference

1 reference

4

1 reference

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7 January 2020

author name string

Janice L V Reeve

series ordinal

1

1 reference

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7 January 2020

Angela M Duffy

series ordinal

2

1 reference

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7 January 2020

Timothy O'Brien

series ordinal

3

1 reference

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7 January 2020

publication date

1 July 2005

1 reference

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Journal of Cellular and Molecular Medicine

7 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16202209%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

9

1 reference

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7 January 2020

issue

3

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7 January 2020

page(s)

609-622

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Caspase-independent cell deaths

7 January 2020

cites work

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Apoptosis during cardiovascular development

21 January 2018

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Normal and abnormal consequences of apoptosis in the human heart. From postnatal morphogenesis to paroxysmal arrhythmias

21 January 2018

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Losing heart: the role of apoptosis in heart disease--a novel therapeutic target?

21 January 2018

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Mechanisms of apoptosis in the heart

21 January 2018

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Ischemia/reperfusion injury at the intersection with cell death.

21 January 2018

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Levels of soluble Fas ligand in myocarditis.

21 January 2018

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Pharmacologic modulation of the immune interaction between cytotoxic lymphocytes and ventricular myocytes

21 January 2018

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Portrait of a killer: the mitochondrial apoptosome emerges from the shadows

21 January 2018

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Apoptosome formation and caspase activation: is it different in the heart?

21 January 2018

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Caspase activation and mitochondrial cytochrome C release during hypoxia-mediated apoptosis of adult ventricular myocytes

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Lack of Apaf-1 expression confers resistance to cytochrome c-driven apoptosis in cardiomyocytes

21 January 2018

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Caspases involved in ER stress-mediated cell death

21 January 2018

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Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

21 January 2018

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Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis

21 January 2018

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Doxorubicin treatment in vivo activates caspase-12 mediated cardiac apoptosis in both male and female rats

21 January 2018

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Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

21 January 2018

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Mitochondria and Ca(2+)in cell physiology and pathophysiology

21 January 2018

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Mitochondrial function: the heart of myocardial preservation

21 January 2018

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Organelle-specific initiation of cell death pathways

21 January 2018

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The adenine nucleotide translocase: a central component of the mitochondrial permeability transition pore and key player in cell death.

21 January 2018

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Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

21 January 2018

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Dinitrophenol, cyclosporin A, and trimetazidine modulate preconditioning in the isolated rat heart: support for a mitochondrial role in cardioprotection

21 January 2018

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Staurosporine-induced apoptosis in cardiomyocytes: A potential role of caspase-3.

21 January 2018

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Essential myosin light chain as a target for caspase-3 in failing myocardium

21 January 2018

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Functional consequences of caspase activation in cardiac myocytes

21 January 2018

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Hypoxia predisposes neonatal rat ventricular myocytes to apoptosis induced by activation of the Fas (CD95/Apo-1) receptor: Fas activation and apoptosis in hypoxic myocytes

21 January 2018

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Reactive oxygen species regulate FLICE inhibitory protein (FLIP) and susceptibility to Fas-mediated apoptosis in cardiac myocytes

21 January 2018

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X-linked IAP is a direct inhibitor of cell-death proteases

21 January 2018

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Natural cellular inhibitors of caspases

21 January 2018

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XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs.

21 January 2018

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Solution structure of human survivin and its binding interface with Smac/Diablo

21 January 2018

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The Bcl-2 protein family: arbiters of cell survival

21 January 2018

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Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins

21 January 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

21 January 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

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Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator

21 January 2018

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Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

21 January 2018

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Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

21 January 2018

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The apoptotic regulatory protein ARC (apoptosis repressor with caspase recruitment domain) prevents oxidant stress-mediated cell death by preserving mitochondrial function

21 January 2018

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ARC, an inhibitor of apoptosis expressed in skeletal muscle and heart that interacts selectively with caspases

21 January 2018

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ARC inhibits cytochrome c release from mitochondria and protects against hypoxia-induced apoptosis in heart-derived H9c2 cells

21 January 2018

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TAT protein transduction into isolated perfused hearts: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective

21 January 2018

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Biologic rationale for the use of beta-blockers in the treatment of heart failure

21 January 2018

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Bid is cleaved by calpain to an active fragment in vitro and during myocardial ischemia/reperfusion

21 January 2018

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Anti-apoptotic effect of benidipine, a long-lasting vasodilating calcium antagonist, in ischaemic/reperfused myocardial cells

21 January 2018

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Antiapoptotic mechanisms of benidipine in the ischemic/reperfused heart

21 January 2018

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Modulation of mitochondrial Ca(2+) homeostasis by Bcl-2.

21 January 2018

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BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death

21 January 2018

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Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury.

21 January 2018

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Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha

21 January 2018

1 reference

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Progressive apoptotic cell death triggered by transient oxidative insult in H9c2 rat ventricular cells: a novel pattern of apoptosis and the mechanisms.

21 January 2018

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Overexpression of tumor necrosis factor-alpha increases production of hydroxyl radical in murine myocardium

21 January 2018

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Overexpression of MnSOD protects against myocardial ischemia/reperfusion injury in transgenic mice.

21 January 2018

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Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion

21 January 2018

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Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury

21 January 2018

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Effect of caspase inhibitors on myocardial infarct size and myocyte DNA fragmentation in the ischemia-reperfused rat heart

21 January 2018

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Pathways of chaperone-mediated protein folding in the cytosol

21 January 2018

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Stable high level expression of a transfected human HSP70 gene protects a heart-derived muscle cell line against thermal stress

21 January 2018

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The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

21 January 2018

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Hsp27 negatively regulates cell death by interacting with cytochrome c.

21 January 2018

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Hsp72 inhibits apoptosis upstream of the mitochondria and not through interactions with Apaf-1.

21 January 2018

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Cytosolic heat shock protein 60, apoptosis, and myocardial injury

21 January 2018

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HSP60, Bax, and cardiac apoptosis

21 January 2018

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Negative regulation of the Apaf-1 apoptosome by Hsp70

21 January 2018

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Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

21 January 2018

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Translational control in virus-infected cells: models for cellular stress responses

21 January 2018

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Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone hsp70.

21 January 2018

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Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance

21 January 2018

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Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

21 January 2018

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Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning

21 January 2018

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Postconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting events in the early minutes of reperfusion

21 January 2018

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Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-Akt pathway

21 January 2018

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Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection.

21 January 2018

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Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection?

21 January 2018

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Myocardial K(ATP) channels in preconditioning

21 January 2018

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Brief hypoxia before normoxic reperfusion (postconditioning) protects the heart against ischemia-reperfusion injury by preventing mitochondria peroxyde production and glutathione depletion

21 January 2018

1 reference

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Role of mitochondria in cell apoptosis during hepatic ischemia-reperfusion injury and protective effect of ischemic postconditioning

21 January 2018

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Involvement of CD95/Apo1/Fas in Cell Death After Myocardial Ischemia

21 January 2018

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Tissue expression and immunolocalization of tumor necrosis factor-alpha in postinfarction dysfunctional myocardium

21 January 2018

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12 December 2020

Fas expression and apoptosis correlate with cardiac dysfunction in patients with dilated cardiomyopathy

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Apoptosis: cell death defined by caspase activation

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Regulation of cardiomyocyte apoptosis in ischemic reperfused mouse heart by glutathione peroxidase

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Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo

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The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes

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HSP27 inhibits cytochrome c-dependent activation of procaspase-9.

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Opposing effects of beta(1)- and beta(2)-adrenergic receptors on cardiac myocyte apoptosis : role of a pertussis toxin-sensitive G protein

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Beneficial effects of vitamin E treatment in acute myocardial infarction

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Antioxidants attenuate myocyte apoptosis in the remote non-infarcted myocardium following large myocardial infarction

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Apoptosis in rat cardiac myocytes induced by Fas ligand: priming for Fas-mediated apoptosis with doxorubicin

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Oxidative stress and apoptosis

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Cellular FLIP is expressed in cardiomyocytes and down-regulated in TUNEL-positive grafted cardiac tissues

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12 December 2020

Reduction in myocardial apoptosis associated with overexpression of heat shock protein 70

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12 December 2020

Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice

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12 December 2020

Calcineurin, Mitochondrial Membrane Potential, and Cardiomyocyte Apoptosis

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12 December 2020

Overexpression of tumor necrosis factor- alpha activates both anti- and pro-apoptotic pathways in the myocardium

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12 December 2020

Distinct initiator caspases are required for the induction of apoptosis in cardiac myocytes during ischaemia versus reperfusion injury

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12 December 2020

Heat shock protein 70 gene transfection protects mitochondrial and ventricular function against ischemia-reperfusion injury.

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12 December 2020

Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury

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12 December 2020

Viral gene transfer of the antiapoptotic factor Bcl-2 protects against chronic postischemic heart failure

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Reperfusion, not simulated ischemia, initiates intrinsic apoptosis injury in chick cardiomyocytes

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Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo

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Does Vitamin E Supplementation Prevent Cardiovascular Events?

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Differential effects of membrane and soluble Fas ligand on cardiomyocytes: role in ischemia/reperfusion injury

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Pharmacologic inhibition of intracellular caspases after myocardial infarction attenuates left ventricular remodeling: a potentially novel pathway

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Proteins involved in salvage of the myocardium

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Long-term caspase inhibition ameliorates apoptosis, reduces myocardial troponin-I cleavage, protects left ventricular function, and attenuates remodeling in rats with myocardial infarction

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12 December 2020

Initiation of mitochondrial-mediated apoptosis during cardiac reperfusion

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12 December 2020

Comparison of circulating proinflammatory cytokines and soluble apoptosis mediators in patients with chronic heart failure with versus without symptoms of depression

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12 December 2020

Preinduced molecular chaperones in the endoplasmic reticulum protect cardiomyocytes from lethal injury.

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12 December 2020

HSP60, Bax, apoptosis and the heart.

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Circulating tumour necrosis factor-alpha (cachectin) in myocardial infarction.

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12 December 2020

Four brief periods of myocardial ischemia cause no cumulative ATP loss or necrosis

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12 December 2020

Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes

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12 December 2020

Reperfusion injury induces apoptosis in rabbit cardiomyocytes

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12 December 2020

Expression of inducible stress protein 70 in rat heart myogenic cells confers protection against simulated ischemia-induced injury

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12 December 2020

Specific induction of the 70-kD heat stress proteins by the tyrosine kinase inhibitor herbimycin-A protects rat neonatal cardiomyocytes. A new pharmacological route to stress protein expression?

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12 December 2020

Apoptosis in myocytes in end-stage heart failure

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12 December 2020

Expression of bcl-2 protein, an inhibitor of apoptosis, and Bax, an accelerator of apoptosis, in ventricular myocytes of human hearts with myocardial infarction

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12 December 2020

Apoptosis in ischemic and reperfused rat myocardium

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12 December 2020

Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart

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12 December 2020

Apoptosis in human acute myocardial infarction

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12 December 2020

Mammalian cell death proteases: a family of highly conserved aspartate specific cysteine proteases

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Apoptosis in the failing human heart

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12 December 2020

Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor

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12 December 2020

Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats

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12 December 2020

Tumor necrosis factor in the heart.

1 reference

12 December 2020

Oxidative stress developed during the reperfusion of ischemic myocardium induces apoptosis

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12 December 2020

Age-dependent changes in myocardial susceptibility to zero flow ischemia and reperfusion in isolated perfused rat hearts: relation to antioxidant status

1 reference

12 December 2020

10.1111/J.1582-4934.2005.TB00492.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16202209%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16202209%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference