Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration. (Q36262236)

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English	Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration.	scientific article

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9 April 2020

Galectin-3 released in response to traumatic brain injury acts as an alarmin orchestrating brain immune response and promoting neurodegeneration (English)

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9 April 2020

traumatic brain injury

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Alejandro Carrillo-Jiménez

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Miguel Angel Burguillos

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Ping Kei Yip

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Paul King

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Alexander Michael Scott Egerton

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Ashray Jayaram Shetty

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Jordi L Tremoleda

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Meirion Davies

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Tomas Deierborg

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John V Priestley

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Guy Charles Brown

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Adina Teodora Michael-Titus

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Jose Luis Venero

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27 January 2017

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Scientific Reports

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41689

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27 January 2017

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https://scigraph.springernature.com/pub.10.1038/srep41689

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Brain trauma elicits non-canonical macrophage activation states

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The change of plasma galectin-3 concentrations after traumatic brain injury

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30 September 2017

High-throughput proteomics reveal alarmins as amplifiers of tissue pathology and inflammation after spinal cord injury

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Focal release of neurotrophic factors by biodegradable microspheres enhance motor and sensory axonal regeneration in vitro and in vivo

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Call Off the Dog(ma): M1/M2 Polarization Is Concurrent following Traumatic Brain Injury

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PSA-NCAM positive neural progenitors stably expressing BDNF promote functional recovery in a mouse model of spinal cord injury

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Functional polarization of neuroglia: Implications in neuroinflammation and neurological disorders.

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Factors that may improve outcomes of early traumatic brain injury care: prospective multicenter study in Austria

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The Small-Molecule TrkB Agonist 7, 8-Dihydroxyflavone Decreases Hippocampal Newborn Neuron Death After Traumatic Brain Injury

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Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

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Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling

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A Decade of Research on TLR2 Discovering Its Pivotal Role in Glial Activation and Neuroinflammation in Neurodegenerative Diseases

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Blood-brain barrier and traumatic brain injury

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High mobility group box protein-1 promotes cerebral edema after traumatic brain injury via activation of toll-like receptor 4

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Phagocytosis executes delayed neuronal death after focal brain ischemia

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Absence of TLR4 reduces neurovascular unit and secondary inflammatory process after traumatic brain injury in mice

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The pleiotropic effects of galectin-3 in neuroinflammation: a review

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Rod microglia: elongation, alignment, and coupling to form trains across the somatosensory cortex after experimental diffuse brain injury.

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Galectin-3--a jack-of-all-trades in cancer

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Regulated expression of galectin-3, a multifunctional glycan-binding protein, in haematopoietic and non-haematopoietic tissues

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Galectin-3 exerts cytokine-like regulatory actions through the JAK-STAT pathway

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Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury

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Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents

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30 September 2017

Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice

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29 June 2018

A Single Bolus of Docosahexaenoic Acid Promotes Neuroplastic Changes in the Innervation of Spinal Cord Interneurons and Motor Neurons and Improves Functional Recovery after Spinal Cord Injury.

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22 September 2018

Lack of galectin-3 improves the functional outcome and tissue sparing by modulating inflammatory response after a compressive spinal cord injury.

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22 September 2018

A New Panel of Blood Biomarkers for the Diagnosis of Mild Traumatic Brain Injury/Concussion in Adults.

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22 September 2018

TLR4 inhibitor resatorvid provides neuroprotection in experimental traumatic brain injury: implication in the treatment of human brain injury.

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22 September 2018

Genetic ablation of toll-like receptor 2 reduces secondary brain injury caused by cortical contusion in mice.

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22 September 2018

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22 September 2018

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22 September 2018

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22 September 2018

Gene expression profile changes are commonly modulated across models and species after traumatic brain injury.

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22 September 2018

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22 September 2018

Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma.

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22 September 2018

Nerve growth factor-mediated expression of galectin-3 in mouse dorsal root ganglion neurons

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Embryonic implantation in galectin 1/galectin 3 double mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/28128358

12 December 2020

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Identifiers

10.1038/SREP41689

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Europe PubMed Central

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9 April 2020

1 reference

Europe PubMed Central

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9 April 2020

1 reference

Europe PubMed Central

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9 April 2020

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