Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice (Q41357385)

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scientific article published on 4 April 2015

Language	Label	Description	Also known as
English	Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice	scientific article published on 4 April 2015

Statements

scholarly article

1 reference

Europe PubMed Central

29 September 2017

Local Injection of Lenti-BDNF at the Lesion Site Promotes M2 Macrophage Polarization and Inhibits Inflammatory Response After Spinal Cord Injury in Mice (English)

1 reference

Europe PubMed Central

29 September 2017

author name string

Xin-Chao Ji

1

1 reference

Europe PubMed Central

29 September 2017

Yuan-Yuan Dang

2

1 reference

Europe PubMed Central

29 September 2017

Hong-Yan Gao

3

1 reference

Europe PubMed Central

29 September 2017

Zhao-Tao Wang

4

1 reference

Europe PubMed Central

29 September 2017

Mou Gao

5

1 reference

Europe PubMed Central

29 September 2017

Yi Yang

6

1 reference

Europe PubMed Central

29 September 2017

Hong-Tian Zhang

7

1 reference

Europe PubMed Central

29 September 2017

Ru-Xiang Xu

8

1 reference

Europe PubMed Central

29 September 2017

publication date

4 April 2015

1 reference

Europe PubMed Central

29 September 2017

Cellular and Molecular Neurobiology

1 reference

Europe PubMed Central

29 September 2017

35

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Europe PubMed Central

29 September 2017

6

1 reference

Europe PubMed Central

29 September 2017

881-890

1 reference

Europe PubMed Central

29 September 2017

https://scigraph.springernature.com/pub.10.1007/s10571-015-0182-x

0 references

Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Inflammation and axon regeneration

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: superiority to camp-mediated effects.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Differential effects of brain-derived neurotrophic factor and neurotrophin-3 on hindlimb function in paraplegic rats

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

High resolution diffusion tensor imaging of axonal damage in focal inflammatory and demyelinating lesions in rat spinal cord.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

p53 Regulates the neuronal intrinsic and extrinsic responses affecting the recovery of motor function following spinal cord injury.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Endogenous BDNF regulates induction of intrinsic neuronal growth programs in injured sensory neurons.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Alternative activation of macrophages: mechanism and functions

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Targeted delivery of TrkB receptor to phrenic motoneurons enhances functional recovery of rhythmic phrenic activity after cervical spinal hemisection.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Blockade of interleukin-6 signaling inhibits the classic pathway and promotes an alternative pathway of macrophage activation after spinal cord injury in mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Another barrier to regeneration in the CNS: activated macrophages induce extensive retraction of dystrophic axons through direct physical interactions

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Effects of brain-derived neurotrophic factor (BDNF) on compression-induced spinal cord injury: BDNF attenuates down-regulation of superoxide dismutase expression and promotes up-regulation of myelin basic protein expression.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Intranasal brain-derived neurotrophic factor protects brain from ischemic insult via modulating local inflammation in rats.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Inflammatory-mediated injury and repair in the traumatically injured spinal cord

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Local acute application of BDNF in the lesioned spinal cord anti-inflammatory and anti-oxidant effects

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Development and characterization of a novel, graded model of clip compressive spinal cord injury in the mouse: Part 1. Clip design, behavioral outcomes, and histopathology

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Neurotrophin signal transduction in the nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Transcriptional regulation of macrophage polarization: enabling diversity with identity

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Targeting the shift from M1 to M2 macrophages in experimental autoimmune encephalomyelitis mice treated with fasudil

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Motoneuron BDNF/TrkB signaling enhances functional recovery after cervical spinal cord injury.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Brain-derived neurotrophic factor but not forced arm use improves long-term outcome after photothrombotic stroke and transiently upregulates binding densities of excitatory glutamate receptors in the rat brain

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Macrophage activation and polarization: nomenclature and experimental guidelines

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Transplantation of mesenchymal stem cells promotes an alternative pathway of macrophage activation and functional recovery after spinal cord injury

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Neurotrophins inhibit major histocompatibility class II inducibility of microglia: involvement of the p75 neurotrophin receptor

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

SOCS3 deficiency promotes M1 macrophage polarization and inflammation.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Brain derived neurotrophic factor and insulin like growth factor-1 attenuate upregulation of nitric oxide synthase and cell injury following trauma to the spinal cord. An immunohistochemical study in the rat.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

PTPsigma is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Alternatively activated macrophages in spinal cord injury and remission: another mechanism for repair?

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Macrophage plasticity and polarization: in vivo veritas

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Regenerative growth of corticospinal tract axons via the ventral column after spinal cord injury in mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

BDNF: the career of a multifaceted neurotrophin in spinal cord injury

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Programmed death 1 deficiency induces the polarization of macrophages/microglia to the M1 phenotype after spinal cord injury in mice

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

The relationships among the severity of spinal cord injury, residual neurological function, axon counts, and counts of retrogradely labeled neurons after experimental spinal cord injury

1 reference

https://api.crossref.org/works/10.1007%2FS10571-015-0182-X

21 January 2018

Neurotrophins and their receptors in human lingual tonsil: an immunohistochemical analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25840805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term viral brain-derived neurotrophic factor delivery promotes spasticity in rats with a cervical spinal cord hemisection

1 reference

https://pubmed.ncbi.nlm.nih.gov/25840805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25840805

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10571-015-0182-X

1 reference

Europe PubMed Central

29 September 2017

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0 references

1 reference

Europe PubMed Central

29 September 2017

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