HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains (Q36254167)

13 August 2017

HTLV-1 Tax Induces Formation of the Active Macromolecular IKK Complex by Generating Lys63- and Met1-Linked Hybrid Polyubiquitin Chains (English)

1 reference

Human T-lymphotropic virus 1

13 August 2017

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1

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10 June 2020

Fuminori Tokunaga

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10 June 2020

Jin Gohda

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10 June 2020

Hiroyasu Nakano

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10 June 2020

Kazuhiro Iwai

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10 June 2020

Jun-Ichiro Inoue

16

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10 June 2020

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Eiji Goto

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10 June 2020

Ginga Komatsu

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10 June 2020

Yasushi Saeki

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10 June 2020

Keiji Tanaka

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10 June 2020

Hirotaka Takahashi

8

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10 June 2020

Tatsuya Sawasaki

9

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10 June 2020

Satoshi Inoue

10

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10 June 2020

Hiroyuki Oshiumi

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10 June 2020

Tsukasa Seya

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10 June 2020

Yuetsu Tanaka

14

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10 June 2020

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19 January 2017

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13 August 2017

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10 June 2020

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13

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10 June 2020

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10 June 2020

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Creative Commons Attribution 4.0 International

10 June 2020

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19 January 2017

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cites work

HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains

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HTLV-1 Tax Stimulates Ubiquitin E3 Ligase, Ring Finger Protein 8, to Assemble Lysine 63-Linked Polyubiquitin Chains for TAK1 and IKK Activation.

30 September 2017

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Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling

30 September 2017

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30 September 2017

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OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

30 September 2017

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HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways

30 September 2017

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Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation

30 September 2017

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p47 negatively regulates IKK activation by inducing the lysosomal degradation of polyubiquitinated NEMO.

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Tropical spastic paraparesis and HTLV-1 associated myelopathy: clinical, epidemiological, virological and therapeutic aspects

30 September 2017

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SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis

30 September 2017

1 reference

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SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

The ubiquitin ligase Riplet is essential for RIG-I-dependent innate immune responses to RNA virus infection.

30 September 2017

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Expanding role of ubiquitination in NF-κB signaling

30 September 2017

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c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

30 September 2017

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Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

30 September 2017

1 reference

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Molecular approach to human leukemia: isolation and characterization of the first human retrovirus HTLV-1 and its impact on tumorigenesis in adult T-cell leukemia

30 September 2017

1 reference

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HTLV-I Tax-dependent and -independent events associated with immortalization of human primary T lymphocytes

30 September 2017

1 reference

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Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

30 September 2017

1 reference

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Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling

30 September 2017

1 reference

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NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain

30 September 2017

1 reference

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Direct activation of protein kinases by unanchored polyubiquitin chains

30 September 2017

1 reference

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Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains

30 September 2017

1 reference

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Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation

30 September 2017

1 reference

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Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1

30 September 2017

1 reference

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Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

30 September 2017

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Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation

30 September 2017

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cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

30 September 2017

1 reference

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Shared principles in NF-kappaB signaling

30 September 2017

1 reference

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The human T-cell leukemia virus type 1 Tax oncoprotein requires the ubiquitin-conjugating enzyme Ubc13 for NF-kappaB activation

30 September 2017

1 reference

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HTLV-1 Tax-induced NFkappaB activation is independent of Lys-63-linked-type polyubiquitination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

A ubiquitin ligase complex assembles linear polyubiquitin chains

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kappaB activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Exclusive ubiquitination and sumoylation on overlapping lysine residues mediate NF-kappaB activation by the human T-cell leukemia virus tax oncoprotein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

A human T-cell leukemia virus Tax variant incapable of activating NF-kappaB retains its immortalizing potential for primary T-lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Oncogenic transformation by the tax gene of human T-cell leukemia virus type I in vitro

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

HTLV-I Tax is a zinc-binding protein: role of zinc in Tax structure and function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

A T-cell line derived from normal human cord leukocytes by co-culturing with human leukemic T-cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Monoclonal antibody defining tax protein of human T-cell leukemia virus type-I.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Linear ubiquitin chains: NF-κB signalling, cell death and beyond.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

The parallel reaction monitoring method contributes to a highly sensitive polyubiquitin chain quantification.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Activation of the IκB kinase complex by HTLV-1 Tax requires cytosolic factors involved in Tax-induced polyubiquitination.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Practical cell-free protein synthesis system using purified wheat embryos

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

Mitogen requirements for the in vitro propagation of cutaneous T-cell lymphomas

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5283754

10.1371/JOURNAL.PPAT.1006162

22 September 2018

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28103322%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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10 June 2020

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