Inhibition of CDK-mediated phosphorylation of Smad3 results in decreased oncogenesis in triple negative breast cancer cells (Q36187896)

12 August 2017

Inhibition of CDK-mediated phosphorylation of Smad3 results in decreased oncogenesis in triple negative breast cancer cells (English)

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12 August 2017

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Elizabeth Tarasewicz

1

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12 August 2017

Lisbi Rivas

2

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12 August 2017

Randala Hamdan

3

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12 August 2017

Danijela Dokic

4

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12 August 2017

Vamsi Parimi

5

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12 August 2017

Beatriz Penalver Bernabe

6

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12 August 2017

Alexandra Thomas

7

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12 August 2017

Lonnie D Shea

8

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12 August 2017

Jacqueline S Jeruss

9

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12 August 2017

1 January 2014

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12 August 2017

11

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based on heuristic

inferred from page(s)

published in

Cell Cycle

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12 August 2017

13

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12 August 2017

3191-3201

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12 August 2017

20

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describes a project that uses

12 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4614520/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4614520

based on heuristic

inferred from PubMed Central ID database lookup

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MEK drives cyclin D1 hyperelevation during geroconversion

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1 October 2017

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ShRNA targeting Notch1 sensitizes breast cancer stem cell to paclitaxel

1 October 2017

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CDK4/6 inhibition antagonizes the cytotoxic response to anthracycline therapy

1 October 2017

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1 October 2017

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Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

1 October 2017

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Cdc42 negatively regulates intrinsic migration of highly aggressive breast cancer cells

1 October 2017

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Impact of cyclin E overexpression on Smad3 activity in breast cancer cell lines

1 October 2017

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Dynamic, large-scale profiling of transcription factor activity from live cells in 3D culture

1 October 2017

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Triple-Negative Breast Cancer

1 October 2017

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The TGF-β/Smad pathway induces breast cancer cell invasion through the up-regulation of matrix metalloproteinase 2 and 9 in a spheroid invasion model system

1 October 2017

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Cyclin-dependent kinase 4-mediated phosphorylation inhibits Smad3 activity in cyclin D-overexpressing breast cancer cells

1 October 2017

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Pin1 promotes transforming growth factor-beta-induced migration and invasion

1 October 2017

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Analysis of cyclins A, B1, D1 and E in breast cancer in relation to tumour grade and other prognostic factors

1 October 2017

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Pathology of breast carcinomas after neoadjuvant chemotherapy: an overview with recommendations on specimen processing and reporting

1 October 2017

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TGF-beta-induced epithelial to mesenchymal transition

1 October 2017

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Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

1 October 2017

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The combination of high cyclin E and Skp2 expression in breast cancer is associated with a poor prognosis and the basal phenotype

1 October 2017

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Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity

1 October 2017

1 reference

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Clinical and pathologic aspects of basal-like breast cancers

1 October 2017

1 reference

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How the Smads regulate transcription

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Reversible Smad-dependent signaling between tumor suppression and oncogenesis

1 October 2017

1 reference

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Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

1 October 2017

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Transforming growth factor-beta during carcinogenesis: the shift from epithelial to mesenchymal signaling

1 October 2017

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

1 October 2017

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Breast cancer bone metastasis mediated by the Smad tumor suppressor pathway

1 October 2017

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Activin A mediates growth inhibition and cell cycle arrest through Smads in human breast cancer cells

1 October 2017

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Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts.

1 October 2017

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Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro

1 October 2017

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 October 2017

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Cyclin E and survival in patients with breast cancer

1 October 2017

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Molecular portraits of human breast tumours

1 October 2017

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Sequential dependent enhancement of caspase activation and apoptosis by flavopiridol on paclitaxel-treated human gastric and breast cancer cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Tumor measurement in the nude mouse

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Cellular arrays for large-scale analysis of transcription factor activity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Neoadjuvant chemotherapy, locally advanced breast cancer, and quality of life.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Phase I dose-finding study of weekly docetaxel followed by flavopiridol for patients with advanced solid tumors.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Measurement of residual breast cancer burden to predict survival after neoadjuvant chemotherapy.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

A novel orally active small molecule potently induces G1 arrest in primary myeloma cells and prevents tumor growth by specific inhibition of cyclin-dependent kinase 4/6.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Prognostic value of pathologic complete response after primary chemotherapy in relation to hormone receptor status and other factors.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Acceleration of Smad2 and Smad3 phosphorylation via c-Jun NH(2)-terminal kinase during human colorectal carcinogenesis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Cyclin-dependent kinases regulate the antiproliferative function of Smads

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Change in tumor cellularity of breast carcinoma after neoadjuvant chemotherapy as a variable in the pathologic assessment of response

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Down-regulation of activin, activin receptors, and Smads in high-grade breast cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

Resistance to transforming growth factor beta and activin due to reduced receptor expression in human breast tumor cell lines.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4614520

10.4161/15384101.2014.950126

23 September 2018

Identifiers

DOI

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12 August 2017

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12 August 2017

1 reference