Cyclin-dependent kinases regulate the antiproliferative function of Smads (Q47229633)

12 January 2018

title

Cyclin-dependent kinases regulate the antiproliferative function of Smads (English)

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12 January 2018

author name string

Isao Matsuura

1

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12 January 2018

Natalia G Denissova

2

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12 January 2018

Guannan Wang

3

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12 January 2018

Dongming He

4

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12 January 2018

Jianyin Long

5

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12 January 2018

Fang Liu

6

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12 January 2018

publication date

1 July 2004

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12 January 2018

language of work or name

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volume

430

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issue

6996

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page(s)

226-231

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12 January 2018

TGFbeta signaling in growth control, cancer, and heritable disorders

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TGF-beta signaling in tumor suppression and cancer progression

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p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

21 January 2018

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Transforming Growth Factor β Activates the Promoter of Cyclin-dependent Kinase Inhibitor p15 through an Sp1 Consensus Site

21 January 2018

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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

21 January 2018

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Role of Smad proteins and transcription factor Sp1 in p21(Waf1/Cip1) regulation by transforming growth factor-beta.

21 January 2018

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Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

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Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

21 January 2018

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Defective repression of c-myc in breast cancer cells: A loss at the core of the transforming growth factor beta growth arrest program

21 January 2018

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c-myc Is a Downstream Target of the Smad Pathway

21 January 2018

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E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

21 January 2018

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Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element

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Smad3 Mutant Mice Develop Metastatic Colorectal Cancer

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Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer

21 January 2018

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Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

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Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

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Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

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Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines

21 January 2018

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Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

21 January 2018

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Assay for activity of mammalian cyclin D-dependent kinases CDK4 and CDK6

21 January 2018

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The retinoblastoma protein and cell cycle control

21 January 2018

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7 January 2021

CDK inhibitors: positive and negative regulators of G1-phase progression

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7 January 2021

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

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7 January 2021

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

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7 January 2021

Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

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7 January 2021

Demonstration of cyclin-dependent kinase inhibitory serine/threonine kinase in bovine thymus

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7 January 2021

Identifiers

DOI

10.1038/NATURE02650

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12 January 2018

Dimensions publication ID

1015424137

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12 January 2018