Paneth cell alpha-defensins: peptide mediators of innate immunity in the small intestine (Q36148745)

12 August 2017

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title

Paneth cell alpha-defensins: peptide mediators of innate immunity in the small intestine (English)

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12 August 2017

Andre J Ouellette

1

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12 August 2017

2 June 2005

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Seminars in Immunopathology

12 August 2017

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12 August 2017

27

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12 August 2017

133-146

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12 August 2017

2

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https://scigraph.springernature.com/pub.10.1007/s00281-005-0202-x

12 August 2017

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cites work

Paneth cell defensins and innate immunity of the small bowel

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12 December 2020

CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

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12 December 2020

Modulation of mouse Paneth cell alpha-defensin secretion by mIKCa1, a Ca2+-activated, intermediate conductance potassium channel

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12 December 2020

Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins

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12 December 2020

Intestinal epithelial cell differentiation: new insights from mice, flies and nematodes

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12 December 2020

Paneth cell defensins: endogenous peptide components of intestinal host defense

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12 December 2020

Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel

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12 December 2020

Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides

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12 December 2020

To (I)B(D) or NOD2 (I)B(D)--are paneth cells the answer?

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12 December 2020

Peptide-lipid interactions and mechanisms of antimicrobial peptides.

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12 December 2020

Defensins. Natural peptide antibiotics of human neutrophils

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12 December 2020

Paneth cell differentiation in the developing intestine of normal and transgenic mice

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12 December 2020

Human enteric defensins. Gene structure and developmental expression

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12 December 2020

A novel murine beta -defensin expressed in tongue, esophagus, and trachea.

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12 December 2020

Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria.

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12 December 2020

Killing of Giardia lamblia by cryptdins and cationic neutrophil peptides.

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12 December 2020

NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

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12 December 2020

NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression

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12 December 2020

Secretion of microbicidal alpha-defensins by intestinal Paneth cells in response to bacteria

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12 December 2020

Quantitative interactions between cryptdin-4 amino terminal variants and membranes.

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12 December 2020

Cryptdins: antimicrobial defensins of the murine small intestine

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12 December 2020

Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection.

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12 December 2020

Structure-activity determinants in paneth cell alpha-defensins: loss-of-function in mouse cryptdin-4 by charge-reversal at arginine residue positions

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12 December 2020

Biochemical composition of human saliva in relation to other mucosal fluids

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12 December 2020

Molecular features of adult mouse small intestinal epithelial progenitors

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12 December 2020

Epithelial cell growth and differentiation. III. Promoting diversity in the intestine: conversations between the microflora, epithelium, and diffuse GALT.

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12 December 2020

Cathelicidins: a family of endogenous antimicrobial peptides

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12 December 2020

Interactions of mouse Paneth cell alpha-defensins and alpha-defensin precursors with membranes. Prosegment inhibition of peptide association with biomimetic membranes

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12 December 2020

Crohn's disease: a defensin deficiency syndrome?

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12 December 2020

Peptide localization and gene structure of cryptdin 4, a differentially expressed mouse paneth cell alpha-defensin

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12 December 2020

Activation of Paneth cell alpha-defensins in mouse small intestine

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12 December 2020

Circular minidefensins and posttranslational generation of molecular diversity

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12 December 2020

The cathelicidin family of antimicrobial peptide precursors: a component of the oxygen-independent defense mechanisms of neutrophils.

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12 December 2020

Mucosal T cells regulate Paneth and intermediate cell numbers in the small intestine of T. spiralis-infected mice

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12 December 2020

Localization of human intestinal defensin 5 in Paneth cell granules

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12 December 2020

Defensins: antimicrobial peptides of vertebrates

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12 December 2020

Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

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12 December 2020

Defensins of vertebrate animals

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12 December 2020

Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice

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12 December 2020

Posttranslational processing and targeting of transgenic human defensin in murine granulocyte, macrophage, fibroblast, and pituitary adenoma cell lines

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12 December 2020

The Paneth cell: a source of intestinal lysozyme

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12 December 2020

Antimicrobial peptides of multicellular organisms

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12 December 2020

Cryptdin gene expression in developing mouse small intestine

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12 December 2020

Use of fetal intestinal isografts from normal and transgenic mice to study the programming of positional information along the duodenal-to-colonic axis

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12 December 2020

Defensins: antimicrobial peptides of innate immunity

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12 December 2020

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

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12 December 2020

Cathelicidin antimicrobial peptides are expressed in salivary glands and saliva

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12 December 2020

The NOD2 gene and Crohn's disease: another triumph for molecular genetics

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12 December 2020

Intramolecular inhibition of human defensin HNP-1 by its propiece

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12 December 2020

Commensal host-bacterial relationships in the gut

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12 December 2020

Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier

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12 December 2020

Bacterial overgrowth in the cystic fibrosis transmembrane conductance regulator null mouse small intestine

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12 December 2020

Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis

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12 December 2020

Epithelial antimicrobial peptides: review and significance for oral applications

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12 December 2020

Carbamylcholine- and catecholamine-induced intracellular calcium dynamics of epithelial cells in mouse ileal crypts

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12 December 2020

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

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12 December 2020

Interactions of monomeric rabbit neutrophil defensins with bilayers: comparison with dimeric human defensin HNP-2.

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12 December 2020

Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores

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12 December 2020

Defensins in granules of phagocytic and non-phagocytic cells.

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12 December 2020

Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice.

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12 December 2020

NMR studies of defensin antimicrobial peptides. 2. Three-dimensional structures of rabbit NP-2 and human HNP-1

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12 December 2020

Antimicrobial polypeptides

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12 December 2020

Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses

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12 December 2020

Human intestinal development in a severe-combined immunodeficient xenograft model.

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12 December 2020

NOD2 mutations and Crohn's disease: are Paneth cells and their antimicrobial peptides the link?

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12 December 2020

Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

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12 December 2020

Molecular assessment of intestinal microflora

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12 December 2020

Antimicrobial peptides of vertebrates

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12 December 2020

Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells

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12 December 2020

Functional analysis of the alpha-defensin disulfide array in mouse cryptdin-4

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12 December 2020

Modulation of host antimicrobial peptide (beta-defensins 1 and 2) expression during gastritis.

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12 December 2020

Homodimeric theta-defensins from rhesus macaque leukocytes: isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides

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12 December 2020

NOD2/CARD15 and the Paneth cell: another piece in the genetic jigsaw of inflammatory bowel disease

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12 December 2020

Localized antimicrobial peptide expression in human gingiva

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12 December 2020

Paneth cell alpha-defensins from rhesus macaque small intestine

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12 December 2020

Posttranslational processing of defensins in immature human myeloid cells

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12 December 2020

Mechanism of synergism between antimicrobial peptides magainin 2 and PGLa

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12 December 2020

Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin

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12 December 2020

The multifaceted Paneth cell

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12 December 2020

Crohn's disease and the NOD2 gene: a role for paneth cells

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12 December 2020

Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization

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12 December 2020

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

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12 December 2020

Solution structure of cryptdin-4, a mouse paneth cell alpha-defensin

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12 December 2020

Differentiation and self-renewal in the mouse gastrointestinal epithelium

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12 December 2020

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. IV. Paneth cells

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12 December 2020

Epithelial antibiotics induced at sites of inflammation

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12 December 2020

The intestinal microflora: potentially fertile ground for microbial physiologists

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12 December 2020

Rapid evolution and diversification of mammalian alpha-defensins as revealed by comparative analysis of rodent and primate genes.

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12 December 2020

Structural determinants of procryptdin recognition and cleavage by matrix metalloproteinase-7.

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12 December 2020

Paneth cells of the human small intestine express an antimicrobial peptide gene

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12 December 2020

A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins

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12 December 2020

Enteric defensins: antibiotic peptide components of intestinal host defense

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12 December 2020

Paneth cell trypsin is the processing enzyme for human defensin-5.

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12 December 2020

Cationic defensins arise from charge-neutralized propeptides: a mechanism for avoiding leukocyte autocytotoxicity?

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12 December 2020

Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms

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12 December 2020

Laser capture microdissection of mouse intestine: characterizing mRNA and protein expression, and profiling intermediary metabolism in specified cell populations

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12 December 2020

Structure, function, and membrane integration of defensins

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12 December 2020

Mouse beta-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs.

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12 December 2020

Enteric defensin expression in necrotizing enterocolitis

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12 December 2020

Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity

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12 December 2020

Regulation of human beta-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1.

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12 December 2020

The stem-cell zone of the small intestinal epithelium. I. Evidence from Paneth cells in the adult mouse

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12 December 2020

Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses

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12 December 2020

Expression of the peptide antibiotic human beta-defensin 1 in cultured gingival epithelial cells and gingival tissue

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12 December 2020

Evidence for a NOD2-independent susceptibility locus for inflammatory bowel disease on chromosome 16p.

1 reference

12 December 2020

10.1007/S00281-005-0202-X

Identifiers

DOI

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release_pjqbglduczcknb5mh4a43kopoq

12 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/pjqbglduczcknb5mh4a43kopoq

24 November 2022

mapped directly with Wikidata item

PubMed ID

15931529

1 reference

PubMed ID

15931529