Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses (Q35871609)

scientific article published in June 2004

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English	Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses	scientific article published in June 2004

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scholarly article

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Europe PubMed Central

10 August 2017

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Europe PubMed Central

title

Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses (English)

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Europe PubMed Central

10 August 2017

2

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Europe PubMed Central

10 August 2017

1

Bruce Beutler

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Europe PubMed Central

10 August 2017

3

Louis Shamel

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stated in

Europe PubMed Central

10 August 2017

1 June 2004

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Europe PubMed Central

10 August 2017

Comptes Rendus. Biologies

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Europe PubMed Central

10 August 2017

327

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Europe PubMed Central

10 August 2017

6

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Europe PubMed Central

10 August 2017

571-580

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Europe PubMed Central

10 August 2017

Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

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Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity

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Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor Toll, to human chromosome 4p14.

1 reference

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Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides

1 reference

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Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

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The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

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Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways.

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Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

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Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1

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Small anti-viral compounds activate immune cells via the TLR7 MyD88-dependent signaling pathway

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4.

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Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection

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Drosophila Toll and IL-1 receptor

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Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

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11 October 2022

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

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11 October 2022

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A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses

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Cutting edge: the toll pathway is required for resistance to gram-positive bacterial infections in Drosophila

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Effect of meningococcal endotoxin on the immune response

1 reference

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Unresponsiveness of MyD88-deficient mice to endotoxin

1 reference

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Macrophage differentiation marker MyD88 is a member of the Toll/IL-1 receptor family

1 reference

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Endotoxin-induced maturation of MyD88-deficient dendritic cells

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Control of natural resistance to Salmonella typhimurium and Leishmania donovani in mice by closely linked but distinct genetic loci.

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Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

1 reference

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Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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Lps2: a new locus required for responses to lipopolysaccharide, revealed by germline mutagenesis and phenotypic screening

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Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

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The Primary Role of Lymphoreticnlar Cells in the Mediation of Host Responses to Bacterial Endotoxim

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS

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TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

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TIRAP: an adapter molecule in the Toll signaling pathway

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A Toll-like receptor recognizes bacterial DNA

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Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice

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DOI

10.1016/J.CRVI.2004.03.008

1 reference

stated in

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

PubMed ID

15330256

retrieved

10 August 2017

Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses (Q35871609)

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Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses (Q35871609)

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