Molecular pathogenesis of MEN2-associated tumors (Q36121928)

12 August 2017

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title

Molecular pathogenesis of MEN2-associated tumors (English)

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12 August 2017

Christian A Koch

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12 August 2017

1 January 2005

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12 August 2017

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12 August 2017

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12 August 2017

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3-7

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https://scigraph.springernature.com/pub.10.1007/s10689-004-7022-3

12 August 2017

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cites work

RET germline mutation in codon 791 in a family representing 3 generations from age 5 to age 70 years: should thyroidectomy be performed?

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Crossref

https://api.crossref.org/works/10.1007%2FS10689-004-7022-3

A patient with MEN 2 and multiple mutations of RET in the germline

21 January 2018

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12 December 2020

Amplification and overexpression of mutant RET in multiple endocrine neoplasia type 2-associated medullary thyroid carcinoma.

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12 December 2020

Activation of a novel human transforming gene, ret, by DNA rearrangement

1 reference

12 December 2020

The GDNF/RET signaling pathway and human diseases

1 reference

12 December 2020

Various penetrance of familial medullary thyroid carcinoma in patients with RET protooncogene codon 790/791 germline mutations

1 reference

12 December 2020

Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma

1 reference

12 December 2020

A new verdict for an old convict.

1 reference

12 December 2020

Atypical MEN type 2B associated with two germline RET mutations on the same allele not involving codon 918

1 reference

12 December 2020

Mechanism of activation of the ret proto-oncogene by multiple endocrine neoplasia 2A mutations

1 reference

12 December 2020

Guidelines for diagnosis and therapy of MEN type 1 and type 2.

1 reference

12 December 2020

RET proto-oncogene mutations affecting codon 790/791: A mild form of multiple endocrine neoplasia type 2A syndrome?

1 reference

12 December 2020

Functional receptor for GDNF encoded by the c-ret proto-oncogene

1 reference

12 December 2020

Polymorphisms G691S/S904S of RET as genetic modifiers of MEN 2A

1 reference

12 December 2020

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

1 reference

12 December 2020

A novel somatic mutation in the RET proto-oncogene in familial medullary thyroid carcinoma with a germline codon 768 mutation.

1 reference

12 December 2020

GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF

1 reference

12 December 2020

ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases.

1 reference

12 December 2020

Wildtype Kras2 can inhibit lung carcinogenesis in mice

1 reference

12 December 2020

Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation

1 reference

12 December 2020

Germline and somatic mutations in an oncogene: RET mutations in inherited medullary thyroid carcinoma

1 reference

12 December 2020

Heterogeneous mutation of the RET proto-oncogene in subpopulations of medullary thyroid carcinoma

1 reference

12 December 2020

Modulation of medullary thyroid carcinoma penetrance suggests the presence of modifier genes in a RET transgenic mouse model

1 reference

12 December 2020

The von Hippel-Lindau tumor suppressor gene

1 reference

12 December 2020

Two germline missense mutations at codons 804 and 806 of the RET proto-oncogene in the same allele in a patient with multiple endocrine neoplasia type 2B without codon 918 mutation.

1 reference

12 December 2020

Somatic VHL gene deletion and point mutation in MEN 2A-associated pheochromocytoma

1 reference

12 December 2020

A novel case of multiple endocrine neoplasia type 2A associated with two de novo mutations of the RET protooncogene

1 reference

12 December 2020

A RET double mutation in the germline of a kindred with FMTC.

1 reference

12 December 2020

Genetic testing in endocrinology: lessons learned from experience with multiple endocrine neoplasia type 2 (MEN2).

1 reference

12 December 2020

Familial medullary thyroid carcinoma and prominent corneal nerves associated with the germline V804M and V778I mutations on the same allele of RET.

1 reference

12 December 2020

Germline succinate dehydrogenase subunit D mutation segregating with familial non-RET C cell hyperplasia.

1 reference

12 December 2020

Minireview: RET: normal and abnormal functions

1 reference

12 December 2020

The molecular pathogenesis of hereditary and sporadic adrenocortical and adrenomedullary tumors

1 reference

12 December 2020

New insights into the genetics of familial chromaffin cell tumors

1 reference

12 December 2020

Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.

1 reference

12 December 2020

Molecular mechanisms of RET activation in human cancer.

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12 December 2020

[Management of multiple endocrine neoplasia syndrome type 2 families in association with rare germline mutations of the RET proto-oncogene]

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12 December 2020

Loss of heterozygosity at the RET protooncogene locus in a case of multiple endocrine neoplasia type 2A

1 reference

12 December 2020

Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC

1 reference

12 December 2020

V804M RET mutation and familial medullary thyroid carcinoma: report of a large family with expression of the disease only in the homozygous gene carriers

1 reference

12 December 2020

Duplication of the mutant RET allele in trisomy 10 or loss of the wild-type allele in multiple endocrine neoplasia type 2-associated pheochromocytomas

1 reference

12 December 2020

RET proto-oncogene in the development of human cancer

1 reference

12 December 2020

A homozygous missense mutation in the tyrosine E kinase domain of the RET proto-oncogene in an infant with total intestinal aganglionosis

1 reference

12 December 2020

A novel 9-base pair duplication in RET exon 8 in familial medullary thyroid carcinoma

1 reference

12 December 2020

Somatic mutations of the RET proto-oncogene are not required for tumor development in multiple endocrine neoplasia type 2 (MEN 2) gene carriers

1 reference

12 December 2020

Allelic imbalance of the mutant and wild-type RET allele in MEN 2A-associated medullary thyroid carcinoma

1 reference

12 December 2020

The RET proto-oncogene in human cancers

1 reference

12 December 2020

10.1007/S10689-004-7022-3

Identifiers

DOI

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12 August 2017

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PubMed ID

15883703