The von Hippel-Lindau tumor suppressor gene (Q28203455)

scientific article (publication date: 10 March 2001)

Language	Label	Description	Also known as
English	The von Hippel-Lindau tumor suppressor gene	scientific article (publication date: 10 March 2001)

Statements

instance of

scholarly article

0 references

review article

1 reference

stated in

Europe PubMed Central

title

The von Hippel-Lindau tumor suppressor gene (English)

0 references

2

W G Kaelin

0 references

author name string

K Kondo

series ordinal

1

0 references

language of work or name

English

0 references

publication date

10 March 2001

0 references

published in

Experimental Cell Research

0 references

volume

264

0 references

page(s)

117-25

0 references

issue

1

0 references

cites work

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/20459

Mutations of the VHL tumour suppressor gene in renal carcinoma

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/NG0594-85

Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The von Hippel-Lindau gene product inhibits vascular permeability factor/vascular endothelial growth factor expression in renal cell carcinoma by blocking protein kinase C pathways

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Frequent overexpression of vascular endothelial growth factor gene in human renal cell carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Comparative sequence analysis of the VHL tumor suppressor gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Genotype-phenotype correlations in von Hippel-Lindau disease

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Mutations in the RET proto-oncogene and the von Hippel-Lindau disease tumour suppressor gene in sporadic and syndromic phaeochromocytomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

ZUR FRAGE DER ANGIOMATOSIS RETINae UND IHRER HIRNKOMPLIKATIONEN

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Mutation of the Von Hippel-Lindau tumour suppressor gene in capillary haemangioblastomas of the central nervous system

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Differential response to transforming growth factor (TGF)-alpha and fibroblast growth factor (FGF) in human renal cell carcinomas of the clear cell and papillary types

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Protective function of von Hippel-Lindau protein against impaired protein processing in renal carcinoma cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Transcription-dependent nuclear-cytoplasmic trafficking is required for the function of the von Hippel-Lindau tumor suppressor protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Synthetic peptides define critical contacts between elongin C, elongin B, and the von Hippel-Lindau protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Inhibition of insulin-like growth factor-I-mediated cell signaling by the von Hippel-Lindau gene product in renal cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Somatic mosaicism in von Hippel-Lindau Disease

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Putative control of angiogenesis in hemangioblastomas by the von Hippel-Lindau tumor suppressor gene.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Elongin BC complex prevents degradation of von Hippel-Lindau tumor suppressor gene products

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Drosophila von Hippel-Lindau tumor suppressor complex possesses E3 ubiquitin ligase activity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Expression, ontogeny, and regulation of hypoxia-inducible transcription factors in the human placenta

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Recruitment of a ROC1-CUL1 ubiquitin ligase by Skp1 and HOS to catalyze the ubiquitination of I kappa B alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Hypoxia and human placental development.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

An important von Hippel-Lindau tumor suppressor domain mediates Sp1-binding and self-association

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Von Hippel-Lindau disease maps to the region of chromosome 3 associated with renal cell carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Mosaicism in von Hippel-Lindau disease: lessons from kindreds with germline mutations identified in offspring with mosaic parents

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The Elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, ras, WD-40 repeat, and ankyrin repeat families

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Characterization of the VHL tumor suppressor gene product: localization, complex formation, and the effect of natural inactivating mutations

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

VHL gene deletion and enhanced VEGF gene expression detected in the stromal cells of retinal angioma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

von Hippel-Lindau gene deletion detected in the stromal cell component of a cerebellar hemangioblastoma associated with von Hippel-Lindau disease

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Tumour suppression by the human von Hippel-Lindau gene product

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Polycythemia: mechanisms and management

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Cdc53 targets phosphorylated G1 cyclins for degradation by the ubiquitin proteolytic pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Isolation and characterization of the full-length 3' untranslated region of the human von Hippel-Lindau tumor suppressor gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Oncogenic alterations of metabolism

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Identification of the von Hippel-lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Formation of the VHL-elongin BC tumor suppressor complex is mediated by the chaperonin TRiC.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

von Hippel-Lindau disease

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Studying interactions of four proteins in the yeast two-hybrid system: structural resemblance of the pVHL/elongin BC/hCUL-2 complex with the ubiquitin ligase complex SKP1/cullin/F-box protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Identification of the von Hippel-Lindau disease tumor suppressor gene

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Über eine sehr seltene Erkrankung der Netzhaut

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1-to-S-phase transition and identifies a conserved family of proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Germline mutations in the vhl gene in patients presenting with phaeochromocytomas.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Molecular genetic diagnosis of von Hippel-Lindau disease in familial phaeochromocytoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Ran-mediated nuclear export of the von Hippel-Lindau tumor suppressor protein occurs independently of its assembly with cullin-2

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Conjugation of Nedd8 to CUL1 enhances the ability of the ROC1-CUL1 complex to promote ubiquitin polymerization

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The von Hippel-Lindau tumor suppressor gene is required for cell cycle exit upon serum withdrawal

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Alternate choice of initiation codon produces a biologically active product of the von Hippel Lindau gene with tumor suppressor activity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Cell cycle: cull and destroy

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Direct Interaction of the β-Domain of VHL Tumor Suppressor Protein with the Regulatory Domain of Atypical PKC Isotypes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Molecular genetic analysis of the von Hippel-Lindau disease tumor suppressor gene in familial and sporadic cerebellar hemangioblastomas

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Structure of the VHL-ElonginC-ElonginB complex: implications for VHL tumor suppressor function

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Conditional switching of vascular endothelial growth factor (VEGF) expression in tumors: induction of endothelial cell shedding and regression of hemangioblastoma-like vessels by VEGF withdrawal

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The von Hippel-Lindau tumor suppressor gene inhibits hepatocyte growth factor/scatter factor-induced invasion and branching morphogenesis in renal carcinoma cells

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Inhibition of transcription elongation by the VHL tumor suppressor protein

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Expression of growth factors and growth factor receptors in capillary hemangioblastoma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

VHL induces renal cell differentiation and growth arrest through integration of cell-cell and cell-extracellular matrix signaling

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Lessons from hereditary colorectal cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

SCF and Cullin/Ring H2-based ubiquitin ligases

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Elongin (SIII): a multisubunit regulator of elongation by RNA polymerase II

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Germline and somatic mutations in von Hippel-Lindau disease gene and its significance in the development of kidney cancer

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Haemangioblastoma of the central nervous system in von Hippel-Lindau disease. French VHL Study Group

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1006/EXCR.2000.5139

Identifiers

DOI

10.1006/EXCR.2000.5139

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

240947

OpenCitations bibliographic resource ID

240947

1 reference

stated in

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

240947

The von Hippel-Lindau tumor suppressor gene (Q28203455)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Navigation menu

The von Hippel-Lindau tumor suppressor gene (Q28203455)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Navigation menu

Search