Role of the Exocyst Complex Component Sec6/8 in Genomic Stability (Q36109385)

12 August 2017

Role of the Exocyst Complex Component Sec6/8 in Genomic Stability (English)

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12 August 2017

12

Charles Yeaman

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12 August 2017

Kalpana Mujoo

7

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author name string

Michael J Torres

1

1 reference

12 August 2017

Raj K Pandita

2

1 reference

12 August 2017

Ozlem Kulak

3

1 reference

12 August 2017

Rakesh Kumar

4

1 reference

12 August 2017

Etienne Formstecher

5

1 reference

12 August 2017

Nobuo Horikoshi

6

1 reference

12 August 2017

Clayton R Hunt

8

1 reference

12 August 2017

Yingming Zhao

9

1 reference

12 August 2017

Lawrence Lum

10

1 reference

12 August 2017

Aubhishek Zaman

11

1 reference

12 August 2017

Michael A White

13

1 reference

12 August 2017

Tej K Pandita

14

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12 August 2017

language of work or name

English

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publication date

17 August 2015

1 reference

Molecular and Cellular Biology

12 August 2017

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12 August 2017

35

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12 August 2017

21

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12 August 2017

3633-3645

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4589602/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

MOF phosphorylation by ATM regulates 53BP1-mediated double-strand break repair pathway choice.

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HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-proteasome pathway

2 October 2017

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PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry

2 October 2017

1 reference

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Role of 53BP1 in the regulation of DNA double-strand break repair pathway choice

2 October 2017

1 reference

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RNA splicing: a new player in the DNA damage response

2 October 2017

1 reference

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53BP1: pro choice in DNA repair

2 October 2017

1 reference

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KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling

2 October 2017

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CEP proteins: the knights of centrosome dynasty

2 October 2017

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Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

2 October 2017

1 reference

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Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest

2 October 2017

1 reference

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TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes

2 October 2017

1 reference

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Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair

2 October 2017

1 reference

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ATF2 - at the crossroad of nuclear and cytosolic functions

2 October 2017

1 reference

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Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

2 October 2017

1 reference

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A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20.

2 October 2017

1 reference

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Image-based genome-wide siRNA screen identifies selective autophagy factors

2 October 2017

1 reference

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Suppression of autophagy by FIP200 deletion impairs DNA damage repair and increases cell death upon treatments with anticancer agents

2 October 2017

1 reference

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The emerging role of Mule and ARF in the regulation of base excision repair

2 October 2017

1 reference

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Exo70, a subunit of the exocyst complex, interacts with SNEV(hPrp19/hPso4) and is involved in pre-mRNA splicing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

2 October 2017

1 reference

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2 October 2017

DNA damage and autophagy

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Hallmarks of Cancer: The Next Generation

2 October 2017

1 reference

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Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks

2 October 2017

1 reference

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TBK1 directly engages Akt/PKB survival signaling to support oncogenic transformation

2 October 2017

1 reference

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Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice

2 October 2017

1 reference

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53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

2 October 2017

1 reference

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Dissecting the dynamic turnover of GFP-LC3 in the autolysosome

2 October 2017

1 reference

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Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells

2 October 2017

1 reference

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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

2 October 2017

1 reference

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Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

2 October 2017

1 reference

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Distinct genetic alterations in colorectal cancer

2 October 2017

1 reference

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The genetic landscape of a cell

2 October 2017

1 reference

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DRYGIN: a database of quantitative genetic interaction networks in yeast

2 October 2017

1 reference

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A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability

2 October 2017

1 reference

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Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation

2 October 2017

1 reference

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CBP/p300-mediated acetylation of histone H3 on lysine 56

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Dysfunctional homologous recombination mediates genomic instability and progression in myeloma

2 October 2017

1 reference

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ATF2: a transcription factor that elicits oncogenic or tumor suppressor activities

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Regulation of autophagy by cytoplasmic p53

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Regulation of TIP60 by ATF2 modulates ATM activation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

The genomic landscapes of human breast and colorectal cancers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Hyperthermia activates a subset of ataxia-telangiectasia mutated effectors independent of DNA strand breaks and heat shock protein 70 status

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Interplay between human DNA repair proteins at a unique double-strand break in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

MDC1 interacts with Rad51 and facilitates homologous recombination

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Involvement of human MOF in ATM function

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Protein interaction mapping: a Drosophila case study

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Ultracentrifugation-based approaches to study regulation of Sec6/8 (exocyst) complex function during development of epithelial cell polarity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Role of homologous recombination in carcinogenesis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

The Rho family of small GTPases is involved in epithelial cystogenesis and tubulogenesis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

TP53 mutation in colorectal cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

53BP1, a mediator of the DNA damage checkpoint

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Dissecting p53 tumor suppressor functions in vivo

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Spatial regulation of the exocyst complex by Rho1 GTPase

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Subunit structure of the mammalian exocyst complex

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Regulation of p53 stability by Mdm2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Inhibition of autophagy enhances DNA damage-induced apoptosis by disrupting CHK1-dependent S phase arrest

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Two sides of the same coin: TFIIH complexes in transcription and DNA repair.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Role of mammalian Rad9 in genomic stability and ionizing radiation response.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

The sec6/8 complex is located at neurite outgrowth and axonal synapse-assembly domains.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4589602

Synthetic Genetic Array (SGA) Analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26283729

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The exocyst is a Ral effector complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26283729

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00768-15

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

26283729

1 reference