Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin (Q36108894)

12 August 2017

Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin (English)

1 reference

12 August 2017

3

1 reference

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12 June 2020

Brendan Michael Duggan

5

1 reference

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12 June 2020

Bradley S. Moore

12

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12 June 2020

Pei-Yuan Qian

13

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12 June 2020

author name string

Zhong-Rui Li

1

1 reference

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12 June 2020

Jie Li

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547923%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Jennifer Y H Lai

4

1 reference

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12 June 2020

Wei-Peng Zhang

6

1 reference

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12 June 2020

Zhi-Long Li

7

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12 June 2020

Yong-Xin Li

8

1 reference

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12 June 2020

Rong-Biao Tong

9

1 reference

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12 June 2020

Ying Xu

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547923%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Dong-Hai Lin

11

1 reference

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12 June 2020

publication date

22 August 2016

1 reference

12 August 2017

Nature Chemical Biology

1 reference

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12 June 2020

volume

12

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12 June 2020

page(s)

773-775

1 reference

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12 June 2020

issue

10

1 reference

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https://scigraph.springernature.com/pub.10.1038/nchembio.2157

12 June 2020

exact match

0 references

cites work

Convergent and Modular Synthesis of Candidate Precolibactins. Structural Revision of Precolibactin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Colibactin: understanding an elusive gut bacterial genotoxin

2 October 2017

1 reference

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The Microbes inside Us and the Race for Colibactin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Critical Intermediates Reveal New Biosynthetic Events in the Enigmatic Colibactin Pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

The colibactin warhead crosslinks DNA.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Gut symbionts from distinct hosts exhibit genotoxic activity via divergent colibactin biosynthesis pathways.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Comparative metabolomics and structural characterizations illuminate colibactin pathway-dependent small molecules.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Intestinal inflammation targets cancer-inducing activity of the microbiota.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Genotoxicity of Escherichia coli Nissle 1917 strain cannot be dissociated from its probiotic activity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Unipro UGENE: a unified bioinformatics toolkit

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

PKS and NRPS release mechanisms

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Escherichia coli induces DNA double-strand breaks in eukaryotic cells.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Biosynthetic multitasking facilitates thalassospiramide structural diversity in marine bacteria.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Characterization of Polyketide Synthase Machinery from the pks Island Facilitates Isolation of a Candidate Precolibactin.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Isolation of a metabolite from the pks island provides insights into colibactin biosynthesis and activity.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

In vivo evidence for a prodrug activation mechanism during colibactin maturation.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

A prodrug resistance mechanism is involved in colibactin biosynthesis and cytotoxicity

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Extraction and detection of DNA from Bacillus anthracis spores and the vegetative cells within 1 min.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Reactivity of 2-halo-2H-azirines. 1. Reactions with nucleophiles

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Dual modes of death induced by etoposide in human epithelial tumor cells allow Bcl-2 to inhibit apoptosis without affecting clonogenic survival.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5030165

Two more pieces of the colibactin genotoxin puzzle from Escherichia coli show incorporation of an unusual 1-aminocyclopropanecarboxylic acid moiety

23 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2157

MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.2157

Identification of NanE as the thioesterase for polyether chain release in nanchangmycin biosynthesis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27547923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Selective isolation of genomic loci from complex genomes by transformation-associated recombination cloning in the yeast Saccharomyces cerevisiae

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27547923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Colibactin biosynthesis and biological activity depend on the rare aminomalonyl polyketide precursor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27547923

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.2157

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547923%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27547923%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference