Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line (Q36014555)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Generation of 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line (English)

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31 December 2019

1

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31 December 2019

author name string

Shigeyuki Uno

2

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31 December 2019

Bin Wang

3

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31 December 2019

Timothy P Dalton

4

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31 December 2019

Daniel W Nebert

5

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31 December 2019

language of work or name

English

0 references

publication date

6 June 2007

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json

Biochemical and Biophysical Research Communications

31 December 2019

published in

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31 December 2019

volume

359

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31 December 2019

issue

3

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31 December 2019

page(s)

635-642

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Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure

31 December 2019

cites work

1 reference

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2 October 2017

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Systematic analysis of head-to-head gene organization: evolutionary conservation and potential biological relevance

2 October 2017

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Proteasome activator PA200 is required for normal spermatogenesis

2 October 2017

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Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate

2 October 2017

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Mosaic analysis with double markers in mice.

2 October 2017

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Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus

2 October 2017

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Interspecies metabolism of heterocyclic aromatic amines and the uncertainties in extrapolation of animal toxicity data for human risk assessment

2 October 2017

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Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

2 October 2017

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Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation

2 October 2017

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Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Engineering chromosomal rearrangements in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Inducible chromosomal translocation of AML1 and ETO genes through Cre/loxP-mediated recombination in the mouse.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Cytochrome P450 CYP1B1 determines susceptibility to 7, 12-dimethylbenz[a]anthracene-induced lymphomas

2 October 2017

1 reference

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How knockout mouse lines will be used to study the role of drug-metabolizing enzymes and their receptors during reproduction and development, and in environmental toxicity, cancer, and oxidative stress

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Cre-mediated site-specific translocation between nonhomologous mouse chromosomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Relationship between "aromatic hydrocarbon responsiveness" and the survival times in mice treated with various drugs and environmental compounds

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Targeted knockout of Cyp1a1 gene does not alter hepatic constitutive expression of other genes in the mouse [Ah] battery

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Human cDNA-expressed cytochrome P450 IA2: mutagen activation and substrate specificity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Constitutive and inducible forms of cytochrome P450 from hepatic mitochondria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994648

Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.

27 July 2018

1 reference

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Theophylline pharmacokinetics: comparison of Cyp1a1(-/-) and Cyp1a2(-/-) knockout mice, humanized hCYP1A1_1A2 knock-in mice lacking either the mouse Cyp1a1 or Cyp1a2 gene, and Cyp1(+/+) wild-type mice.

23 September 2018

1 reference

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Balancer-Cre transgenic mouse germ cells direct the incomplete resolution of a tri-loxP-targeted Cyp1a1 allele, producing a conditional knockout allele.

23 September 2018

1 reference

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Uroporphyrin accumulation in hepatoma cells expressing human or mouse CYP1A2: relation to the role of CYP1A2 in human porphyria cutanea tarda

23 September 2018

1 reference

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Dual renin gene targeting by Cre-mediated interchromosomal recombination

23 September 2018

1 reference

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Cancer chemotherapy using suicide genes

23 September 2018

1 reference

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Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17560947

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Efficient removal of loxP-flanked DNA sequences in a gene-targeted locus by transient expression of Cre recombinase in fertilized eggs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17560947

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BBRC.2007.05.202

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17560947%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

1 reference