A role for the Wilms' tumor protein WT1 in organ development (Q36011404)

11 August 2017

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title

A role for the Wilms' tumor protein WT1 in organ development (English)

1 reference

11 August 2017

Holger Scholz

1

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PubMed ID

15653840

11 August 2017

Karin M Kirschner

series ordinal

2

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11 August 2017

1 February 2005

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11 August 2017

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11 August 2017

20

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11 August 2017

54-59

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The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.

11 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Donor splice-site mutations in WT1 are responsible for Frasier syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Nephrogenic rests and the pathogenesis of Wilms tumor: developmental and clinical considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

RNA binding by the Wilms tumor suppressor zinc finger proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Development of an siRNA-based method for repressing specific genes in renal organ culture and its use to show that the Wt1 tumour suppressor is required for nephron differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Alternative splicing and genomic structure of the Wilms tumor gene WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

The genetics of Wilms' tumor--a case of disrupted development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

The Wilms tumor suppressor gene wt1 is required for development of the spleen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

E-cadherin is a WT1 target gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

An RNA recognition motif in Wilms' tumour protein (WT1) revealed by structural modelling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

WT-1 is required for early kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Kidney morphogenesis: cellular and molecular regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Wilms tumor and the WT1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

The origin, formation and developmental significance of the epicardium: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

WT1 regulates the expression of the major glomerular podocyte membrane protein Podocalyxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Roles of the podocyte in glomerular function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

The candidate Wilms' tumour gene is involved in genitourinary development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Internal translation initiation generates novel WT1 protein isoforms with distinct biological properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

WT1 proteins: functions in growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

RNA editing in the Wilms' tumor susceptibility gene, WT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Erythropoietin and retinoic acid, secreted from the epicardium, are required for cardiac myocyte proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Podocyte cytoskeleton is connected to the integral membrane protein podocalyxin through Na+/H+-exchanger regulatory factor 2 and ezrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

The Wilms' tumor suppressor Wt1 is expressed in the coronary vasculature after myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

The Wilms' tumor gene Wt1 is required for normal development of the retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Oxygen‐regulated expression of the Wilms’ tumor suppressorWt1involves hypoxia‐inducible factor‐1 (HIF‐1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

Cadherins as Modulators of Cellular Phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FPHYSIOL.00048.2004

10.1152/PHYSIOL.00048.2004

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15653840