A zinc finger truncation of murine WT1 results in the characteristic urogenital abnormalities of Denys-Drash syndrome (Q28584838)

GOA release 2020-03-11

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C. E. Patek

1

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31 January 2017

M. H. Little

2

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31 January 2017

S. Fleming

3

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31 January 2017

C. Miles

4

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31 January 2017

J. P. Charlieu

5

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31 January 2017

A. R. Clarke

6

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31 January 2017

K. Miyagawa

7

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31 January 2017

S. Christie

8

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31 January 2017

J. Doig

9

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31 January 2017

D. J. Harrison

10

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31 January 2017

D. J. Porteous

11

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31 January 2017

A. J. Brookes

12

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31 January 2017

M. L. Hooper

13

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31 January 2017

N. D. Hastie

Proceedings of the National Academy of Sciences of the United States of America

14

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31 January 2017

language of work or name

English

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publication date

16 March 1999

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31 January 2017

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31 January 2017

96

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31 January 2017

6

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31 January 2017

2931–2936

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31 January 2017

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

WT-1 is required for early kidney development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

17 March 2017

The Denys-Drash syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Analysis of WT1 target gene expression in stably transfected cell lines

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

E1B 55K sequesters WT1 along with p53 within a cytoplasmic body in adenovirus-transformed kidney cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Overlapping RNA and DNA binding domains of the wt1 tumor suppressor gene product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Donor splice-site mutations in WT1 are responsible for Frasier syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

A clinical overview of WT1 gene mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Identification of nuclear localization signals within the zinc fingers of the WT1 tumor suppressor gene product

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Truncated WT1 mutants alter the subnuclear localization of the wild-type protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Dicistronic targeting constructs: reporters and modifiers of mammalian gene expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

WT1-mediated transcriptional activation is inhibited by dominant negative mutant proteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

High incidence of XXY and XYY males among the offspring of female chimeras from embryonic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Antagonism of WT1 activity by protein self-association.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

The candidate Wilms' tumour gene is involved in genitourinary development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

In situ analysis of fetal, prepuberal and adult XX—XY chimaeric mouse testes: Sertoli cells are predominantly, but not exclusively, XY

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Production of homozygous mutant ES cells with a single targeting construct

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

A dominant mutation in the Wilms tumor gene WT1 cooperates with the viral oncogene E1A in transformation of primary kidney cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Equivalent expression of paternally and maternally inherited WT1 alleles in normal fetal tissue and Wilms' tumours

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

A mouse model of the aniridia-Wilms tumor deletion syndrome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Hypoxanthine phosphoribosyl transferase deficiency, haematopoiesis and fertility in the mouse

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Characterization of monoclonal antibodies directed to the amino-terminus of the WT1, Wilms' tumor suppressor protein.

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.6.2931

Efficient modification of RNA by porphyrin cation photochemistry: monitoring the folding of coaxially stacked RNA helices in tRNA(Phe) and the human immunodeficiency virus type 1 rev response element RNA.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.6.2931

Effects of Denys-Drash syndrome point mutations on the DNA binding activity of the Wilms' tumor suppressor protein WT1.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15872

Sex chimaerism, fertility and sex determination in the mouse

27 November 2018

1 reference

12 December 2020

A novel insertional mutation at the third zinc finger coding region of the WT1 gene in Denys-Drash syndrome

1 reference

12 December 2020

A series of vectors that simplify mammalian gene targeting

1 reference

12 December 2020

Expression of WT1 protein in fetal kidneys and Wilms tumors

1 reference

12 December 2020

Spontaneous nephroblastoma in a strain CE/J mouse. A case report

1 reference

12 December 2020

DNA binding capacity of the WT1 protein is abolished by Denys—Drash syndrome WT1 point mutations

1 reference

12 December 2020

A non-AUG translational initiation event generates novel WT1 isoforms

1 reference

12 December 2020

Extragonadal teratocarcinoma derived from embryonal stem cells in chimaeric mice

1 reference

12 December 2020