1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway. (Q35995199)

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English	1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway.	scientific article

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2 January 2020

1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway (English)

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2 January 2020

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primary metabolite

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Stefan Chlopicki

1

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2 January 2020

Andrzej Mogielnicki

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2 January 2020

Magdalena Bartus

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2 January 2020

Jerzy Marian Gębicki

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2 January 2020

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J Swies

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2 January 2020

W Buczko

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2 January 2020

M Lomnicka

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2 January 2020

J Adamus

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16 July 2007

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2 January 2020

British Journal of Pharmacology

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2 January 2020

152

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2 January 2020

230-239

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2 January 2020

2

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2 January 2020

Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities

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2 October 2017

GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing

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2 October 2017

Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid

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2 October 2017

Beraprost sodium, a prostacyclin (PGI) analogue, ameliorates concanavalin A-induced liver injury in mice

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2 October 2017

Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD+ in fungi and humans

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2 October 2017

Nicotinamide: necessary nutrient emerges as a novel cytoprotectant for the brain

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Prevention of experimental carotid and coronary artery thrombosis by the glycoprotein IIb/IIIa receptor antagonist CRL42796

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2 October 2017

Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo

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2 October 2017

Human nicotinamide N-methyltransferase pharmacogenetics: gene sequence analysis and promoter characterization

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2 October 2017

Focus on prostacyclin and its novel mimetics

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2 October 2017

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2 October 2017

Bioassay of prostacyclin and endothelium-derived relaxing factor (EDRF) from porcine aortic endothelial cells

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11 July 2018

Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study.

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23 September 2018

Paradoxical effects of fenofibrate and nicotinic acid in apo E-deficient mice

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Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.

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23 September 2018

Nicotinamide trials in diabetes intervention. Does a metabolite provide benefit?

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23 September 2018

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23 September 2018

Nicotinamide inhibits endotoxin-induced monocyte tissue factor expression

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Pentose phosphate pathway coordinates multiple redox-controlled relaxing mechanisms in bovine coronary arteries

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23 September 2018

1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin.

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Nicotinamide modulates mitochondrial membrane potential and cysteine protease activity during cerebral vascular endothelial cell injury

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The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production

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23 September 2018

N-methylation ability for azaheterocyclic amines is higher in Parkinson's disease: nicotinamide loading test

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12 December 2020

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Antithrombotic effect of tissue and plasma type angiotensin converting enzyme inhibitors in experimental thrombosis in rats

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beta-Pyridylcarbinol (Ronicol) releases a prostacyclin-like substance into arterial blood of patients with arteriosclerosis obliterans

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12 December 2020

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Estimation of renal tubular secretion in man, in health and disease, using endogenous N-1-methylnicotinamide

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12 December 2020

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12 December 2020

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Some aspects of tryptophan metabolism in human subjects. I. Nitrogen balances, blood pyridine nucleotides and urinary excretion of N1-methylnicotinamide and N1-methyl-2-pyridone-5-carboxamide on a low-niacin diet

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Human nicotinamide N-methyltransferase pharmacogenetics

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Identifiers

10.1038/SJ.BJP.0707383

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2 January 2020

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