Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid (Q24536167)

5 July 2017

Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid (English)

1 reference

5 July 2017

Nicholas B Pike

1

1 reference

PubMed ID

16322787

5 July 2017

language of work or name

English

0 references

publication date

1 December 2005

1 reference

Journal of Clinical Investigation

5 July 2017

1 reference

5 July 2017

115

1 reference

5 July 2017

3400-3403

1 reference

5 July 2017

12

1 reference

GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing

5 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Molecular identification of nicotinic acid receptor

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Molecular identification of high and low affinity receptors for nicotinic acid

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Nicotinic acid: the broad-spectrum lipid drug. A 50th anniversary review

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

The nicotinic acid receptor--a new mechanism for an old drug

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Extended-release niacin for modifying the lipoprotein profile

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Identification of a nicotinic acid receptor: is this the molecular target for the oldest lipid-lowering drug?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Niacin and cholesterol: role in cardiovascular disease (review).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Niacin extended-release/lovastatin: combination therapy for lipid disorders

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

The benefits of niacin in atherosclerosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

New developments in the use of niacin for treatment of hyperlipidemia: new considerations in the use of an old drug.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

Nicotinic Acid and Inhibition of Fat Mobilizing Lipolysis. Present Status of Effects on Lipid Metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1297267

A comparison between nicotinic acid and acipimox in hypertriglyceridaemia--effects on serum lipids, lipoproteins, glucose tolerance and tolerability

30 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16322787

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16322787

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Niacin accelerates intracellular ApoB degradation by inhibiting triacylglycerol synthesis in human hepatoblastoma (HepG2) cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16322787

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI27160

1 reference

release_3pbcvozusnfmdfooeo3uinvk3u

5 July 2017

0 references

PMCID

1297267

1 reference

5 July 2017

1 reference

PubMed ID

16322787