Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing (Q35975147)

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English	Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing	scientific article

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31 March 2020

Detecting DNA double-stranded breaks in mammalian genomes by linear amplification-mediated high-throughput genome-wide translocation sequencing (English)

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31 March 2020

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author name string

Junchao Dong

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31 March 2020

Rohit A Panchakshari

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Frederick W Alt

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Richard L Frock

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31 March 2016

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Nature Protocols

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853-871

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https://scigraph.springernature.com/pub.10.1038/nprot.2016.043

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Transcription-associated processes cause DNA double-strand breaks and translocations in neural stem/progenitor cells.

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Long Neural Genes Harbor Recurrent DNA Break Clusters in Neural Stem/Progenitor Cells.

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2 October 2017

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system

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2 October 2017

Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.

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2 October 2017

Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells

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2 October 2017

RAG Represents a Widespread Threat to the Lymphocyte Genome

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2 October 2017

In vivo genome editing using Staphylococcus aureus Cas9

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2 October 2017

Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells

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2 October 2017

GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases

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2 October 2017

Genome-wide detection of DNA double-stranded breaks induced by engineered nucleases.

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2 October 2017

Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability

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2 October 2017

DNA break mapping reveals topoisomerase II activity genome-wide

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2 October 2017

Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing.

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2 October 2017

Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes

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2 October 2017

A guide to genome engineering with programmable nucleases

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2 October 2017

IgH class switching exploits a general property of two DNA breaks to be joined in cis over long chromosomal distances

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Genome engineering using the CRISPR-Cas9 system

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2 October 2017

Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing

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2 October 2017

Identification of early replicating fragile sites that contribute to genome instability

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2 October 2017

RNA-guided human genome engineering via Cas9

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2 October 2017

Multiplex genome engineering using CRISPR/Cas systems

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2 October 2017

Mapping genomic hotspots of DNA damage by a single-strand-DNA-compatible and strand-specific ChIP-seq method.

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2 October 2017

Classical and alternative end-joining pathways for repair of lymphocyte-specific and general DNA double-strand breaks

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2 October 2017

YAHA: fast and flexible long-read alignment with optimal breakpoint detection

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Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

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2 October 2017

Translocation-capture sequencing reveals the extent and nature of chromosomal rearrangements in B lymphocytes

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2 October 2017

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2 October 2017

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2 October 2017

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.

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Cellular responses to DNA double-strand breaks after low-dose gamma-irradiation

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2 October 2017

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2 October 2017

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11 July 2018

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11 July 2018

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11 July 2018

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11 July 2018

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24 September 2018

Identifiers

10.1038/NPROT.2016.043

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