From chemoprevention to chemotherapy: common targets and common goals (Q35906984)

11 August 2017

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title

From chemoprevention to chemotherapy: common targets and common goals (English)

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11 August 2017

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3

Oommen V Oommen

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11 August 2017

Bharat B Aggarwal

1

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PubMed ID

15461561

11 August 2017

Yasunari Takada

series ordinal

2

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PubMed ID

15461561

11 August 2017

language of work or name

English

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publication date

1 October 2004

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Expert Opinion on Investigational Drugs

11 August 2017

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11 August 2017

13

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11 August 2017

1327-1338

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11 August 2017

10

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11 August 2017

Inflammation and cancer

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Recent advances in chemoprevention of cancer

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Chemoprevention of cancer

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Cancer chemoprevention with dietary phytochemicals

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Natural products as sources of new drugs over the period 1981-2002.

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Nuclear transcription factor-kappaB as a target for cancer drug development

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NF-kappaB participates in the corticotropin-releasing, hormone-induced regulation of the pituitary proopiomelanocortin gene

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A requirement of nuclear factor-kappaB activation in fear-potentiated startle

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Protein tyrosine kinase inhibitors block tumor necrosis factor-induced activation of nuclear factor-kappaB, degradation of IkappaBalpha, nuclear translocation of p65, and subsequent gene expression

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Anethole blocks both early and late cellular responses transduced by tumor necrosis factor: effect on NF-kappaB, AP-1, JNK, MAPKK and apoptosis

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Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidation

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AP-1 as a regulator of cell life and death

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Promising molecular targets for cancer prevention: AP-1, NF-kappa B and Pdcd4.

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AP-1 in cell proliferation and survival

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Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract

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Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl

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Inhibition of proteasomal function by curcumin induces apoptosis through mitochondrial pathway.

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Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis

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Nuclear factor-kappaB activation: a question of life or death

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Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cells

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Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

21 January 2018

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Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

21 January 2018

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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

21 January 2018

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The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

21 January 2018

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Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

21 January 2018

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Inhibition of growth and survival of human head and neck squamous cell carcinoma cells by curcumin via modulation of nuclear factor-kappaB signaling

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Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol

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Resveratrol Induces Downregulation in Survivin Expression and Apoptosis in HTLV-1-Infected Cell Lines: A Prospective Agent for Adult T Cell Leukemia Chemotherapy

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Untangling the ErbB signalling network

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Predictive factors for epidermal growth factor receptor inhibitors--the bull's-eye hits the arrow

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Regulation of proliferation, survival and apoptosis by members of the TNF superfamily

21 January 2018

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Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells

21 January 2018

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Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells

21 January 2018

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Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibition of ERK1/2 and AKT kinases.

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Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins

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STAT proteins: novel molecular targets for cancer drug discovery

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Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

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Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia

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NF-κB-mediated Induction ofmdr1bExpression by Insulin in Rat Hepatoma Cells

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Modulation of P-glycoprotein expression and function by curcumin in multidrug-resistant human KB cells

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Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites.

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Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols

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Inhibitors of cyclo-oxygenase 2: a new class of anticancer agents?

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Cigarette smoke condensate activates nuclear transcription factor-kappaB through phosphorylation and degradation of IkappaB(alpha): correlation with induction of cyclooxygenase-2.

21 January 2018

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The development of COX2 inhibitors

21 January 2018

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Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells

21 January 2018

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Flavopiridol inhibits NF-kappaB activation induced by various carcinogens and inflammatory agents through inhibition of IkappaBalpha kinase and p65 phosphorylation: abrogation of cyclin D1, cyclooxygenase-2, and matrix metalloprotease-9.

21 January 2018

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Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.

21 January 2018

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Resveratrol suppresses the angiogenesis and tumor growth of gliomas in rats

21 January 2018

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VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG), in B-cell chronic lymphocytic leukemia

21 January 2018

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A novel cyclin encoded by a bcl1-linked candidate oncogene

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Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation

21 January 2018

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Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.

21 January 2018

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Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells

21 January 2018

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Silibinin decreases prostate-specific antigen with cell growth inhibition via G1 arrest, leading to differentiation of prostate carcinoma cells: implications for prostate cancer intervention

21 January 2018

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Transcriptional regulation of glutathione S-transferase P1-1 in human leukemia

21 January 2018

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Induction of apoptosis by curcumin: mediation by glutathione S-transferase P1-1 inhibition

21 January 2018

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Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis

21 January 2018

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Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multidrug resistance.

21 January 2018

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Silibinin sensitizes human prostate carcinoma DU145 cells to cisplatin- and carboplatin-induced growth inhibition and apoptotic death

21 January 2018

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Enhanced radiosensitization and chemosensitization in NF-kappaB-suppressed human oral cancer cells via the inhibition of gamma-irradiation- and 5-FU-induced production of IL-6 and IL-8.

21 January 2018

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Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3.

21 January 2018

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Modulation of radiation-induced protein kinase C activity by phenolics

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10.1517/13543784.13.10.1327

21 January 2018

Identifiers

DOI

1 reference

11 August 2017

1 reference

PubMed ID

15461561