Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response (Q35904260)

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scientific article published on 17 April 2015

Language	Label	Description	Also known as
English	Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response	scientific article published on 17 April 2015

Statements

scholarly article

1 reference

Europe PubMed Central

11 August 2017

Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response (English)

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Europe PubMed Central

11 August 2017

toll-like receptor

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based on heuristic

inferred from title

Rossella Sartorius

1

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9 June 2020

Luciana D'Apice

2

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9 June 2020

5

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9 June 2020

Maria Antonietta De Matteis

10

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9 June 2020

Alfredo Ciccodicola

11

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9 June 2020

Piergiuseppe De Berardinis

12

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9 June 2020

author name string

Maria Trovato

3

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9 June 2020

Fausta Cuccaro

4

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9 June 2020

Maria Giovanna De Leo

6

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9 June 2020

Vincenzo Manuel Marzullo

7

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9 June 2020

Carmelo Biondo

8

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Sabato D'Auria

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9 June 2020

publication date

17 April 2015

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EMBO Molecular Medicine

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9 June 2020

7

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9 June 2020

7

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9 June 2020

973-988

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9 June 2020

Diagnostic Immunization with Bacteriophage ΦX 174 in Patients with Common Variable Immunodeficiency/Hypogammaglobulinemia

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Immunoproteasomes shape the transcriptome and regulate the function of dendritic cells

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TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways

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Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3+ dendritic cells at cross presentation

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UNC93B1 mediates differential trafficking of endosomal TLRs

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DEC-205 is a cell surface receptor for CpG oligonucleotides

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Cancer immunotherapy via dendritic cells

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Cutting edge: a TLR9 cytoplasmic tyrosine motif is selectively required for proinflammatory cytokine production

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OCRL controls trafficking through early endosomes via PtdIns4,5P₂-dependent regulation of endosomal actin

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Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3

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Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

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The immunostimulatory activity of unmethylated and methylated CpG oligodeoxynucleotide is dependent on their ability to colocalize with TLR9 in late endosomes

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Intracellular toll-like receptors

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Transduction of human antigen-presenting cells with integrase-defective lentiviral vector enables functional expansion of primed antigen-specific CD8(+) T cells

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Mature dendritic cells use endocytic receptors to capture and present antigens

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Engineering filamentous phage carriers to improve focusing of antibody responses against peptides

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Plasmacytoid dendritic cells capture and cross-present viral antigens from influenza-virus exposed cells

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TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA.

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

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ARAP1 regulates EGF receptor trafficking and signalling.

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Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I.

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The use of filamentous bacteriophage fd to deliver MAGE-A10 or MAGE-A3 HLA-A2-restricted peptides and to induce strong antitumor CTL responses

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

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The microbial mimic poly IC induces durable and protective CD4+ T cell immunity together with a dendritic cell targeted vaccine

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On the structures of filamentous bacteriophage Ff (fd, f1, M13).

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Comparative analysis of new innovative vaccine formulations based on the use of procaryotic display systems

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Filamentous phage as an immunogenic carrier to elicit focused antibody responses against a synthetic peptide

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Targeting of antigens to activated dendritic cells in vivo cures metastatic melanoma in mice

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Differential expression regulation of the alpha and beta subunits of the PA28 proteasome activator in mature dendritic cells

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

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Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy

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TLR9 is localized in the endoplasmic reticulum prior to stimulation

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In vivo targeting of antigens to maturing dendritic cells via the DEC-205 receptor improves T cell vaccination

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TLR9 signals after translocating from the ER to CpG DNA in the lysosome

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Efficient targeting of protein antigen to the dendritic cell receptor DEC-205 in the steady state leads to antigen presentation on major histocompatibility complex class I products and peripheral CD8+ T cell tolerance

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The dendritic cell receptor for endocytosis, DEC-205, can recycle and enhance antigen presentation via major histocompatibility complex class II-positive lysosomal compartments

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The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing

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Phage therapy gets revitalized.

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12 December 2020

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DEC-205 mediates antigen uptake and presentation by both resting and activated human plasmacytoid dendritic cells

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12 December 2020

based on heuristic

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DEC-205, a 205-kDa protein abundant on mouse dendritic cells and thymic epithelium that is detected by the monoclonal antibody NLDC-145: purification, characterization, and N-terminal amino acid sequence

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Differential and competitive activation of human immune cells by distinct classes of CpG oligodeoxynucleotide

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based on heuristic

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Identifiers

10.15252/EMMM.201404525

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9 June 2020

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9 June 2020

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Europe PubMed Central

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9 June 2020

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