Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid function (Q35880164)

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1 January 2020

title

Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid function (English)

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1 January 2020

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4

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1 January 2020

author name string

Heidi C Shea

series ordinal

1

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1 January 2020

Daphne D Head

series ordinal

2

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1 January 2020

Kenneth D R Setchell

series ordinal

3

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1 January 2020

language of work or name

English

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publication date

29 June 2007

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Proceedings of the National Academy of Sciences of the United States of America

1 January 2020

published in

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1 January 2020

volume

104

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1 January 2020

issue

28

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1 January 2020

page(s)

11526-11533

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LXRS and FXR: the yin and yang of cholesterol and fat metabolism

1 January 2020

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

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Structural basis for bile acid binding and activation of the nuclear receptor FXR

11 July 2018

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A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR

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Molecular genetics of 3beta-hydroxy-Delta5-C27-steroid oxidoreductase deficiency in 16 patients with loss of bile acid synthesis and liver disease

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The enzymes, regulation, and genetics of bile acid synthesis

11 July 2018

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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

11 July 2018

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Control of cholesterol turnover in the mouse

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The bile acid synthetic gene 3beta-hydroxy-Delta(5)-C(27)-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

11 July 2018

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Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

11 July 2018

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Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

11 July 2018

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Targeting genes for self-excision in the germ line

11 July 2018

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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

11 July 2018

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11 July 2018

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Identification of a nuclear receptor for bile acids

11 July 2018

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Biotransformation of monoterpenes, bile acids, and other isoprenoids in anaerobic ecosystems

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New insights into bile acid transport.

11 July 2018

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Disruption of cholesterol 7alpha-hydroxylase gene in mice. II. Bile acid deficiency is overcome by induction of oxysterol 7alpha-hydroxylase.

11 July 2018

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Disruption of cholesterol 7alpha-hydroxylase gene in mice. I. Postnatal lethality reversed by bile acid and vitamin supplementation.

11 July 2018

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11 July 2018

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Isocholic acid formation from 7 alpha,12 alpha-dihydroxy-3-keto-5 beta-cholanoic acid with human liver enzyme.

11 July 2018

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Familial giant cell hepatitis associated with synthesis of 3 beta, 7 alpha-dihydroxy-and 3 beta,7 alpha, 12 alpha-trihydroxy-5-cholenoic acids

11 July 2018

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

11 July 2018

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11 July 2018

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11 July 2018

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Cholic acid mediates negative feedback regulation of bile acid synthesis in mice

11 July 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0705089104

Human liver class I alcohol dehydrogenaseγγ isozyme: the sole cytosolic 3β-hydroxysteroid dehydrogenase of iso bile acids

21 January 2018

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Synthesis of some 3beta-hydroxylated bile acids and the isolation of 3beta, 12alpha-dihydroxy-5beta-cholanic acid from feces

21 January 2018

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12 December 2020

Isolation of some bile acids and sterols from the feces of healthy men

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12 December 2020

Human cecal bile acids: concentration and spectrum

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12 December 2020

Ternary and Quaternary Aqueous Systems Containing Bile Salt, Lecithin, and Cholesterol

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12 December 2020

Metabolism of iso-bile acids in the rat

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12 December 2020

On the nature of dilute aqueous cholesterol suspensions

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12 December 2020

Measurement of rates of cholesterol synthesis using tritiated water

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12 December 2020

Inborn errors of bile acid synthesis.

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12 December 2020

Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver

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12 December 2020

A new cause of progressive intrahepatic cholestasis: 3 beta-hydroxy-C27-steroid dehydrogenase/isomerase deficiency

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12 December 2020

Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

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12 December 2020

Cholesterol 7-hydroxylase knockout mouse: a model for monohydroxy bile acid-related neonatal cholestasis

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0705089104

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17601774%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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1 January 2020

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