A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR (Q27641086)

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3 November 2019

title

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR (English)

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3 November 2019

15

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3 November 2019

13

Joseph P Noel

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3 November 2019

author name string

Michael Downes

1

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3 November 2019

Mark A Verdecia

2

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3 November 2019

A J Roecker

3

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3 November 2019

Robert Hughes

4

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3 November 2019

John B Hogenesch

5

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3 November 2019

Heidi R Kast-Woelbern

6

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3 November 2019

Marianne E Bowman

7

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3 November 2019

Andrew M Anisfeld

9

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3 November 2019

Peter A Edwards

10

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3 November 2019

John M Rosenfeld

11

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3 November 2019

Jacqueline G A Alvarez

12

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3 November 2019

K C Nicolaou

14

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Jean-Luc Ferrer

8

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3 November 2019

publication date

1 April 2003

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3 November 2019

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3 November 2019

volume

11

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3 November 2019

page(s)

1079-1092

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3 November 2019

issue

4

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Identification of a bile acid-responsive element in the human ileal bile acid-binding protein gene. Involvement of the farnesoid X receptor/9-cis-retinoic acid receptor heterodimer

3 November 2019

cites work

1 reference

12 December 2020

Orphan nuclear receptors--new ligands and new possibilities.

1 reference

12 December 2020

The steroid and thyroid hormone receptor superfamily

1 reference

12 December 2020

The farnesoid X-activated receptor mediates bile acid activation of phospholipid transfer protein gene expression

1 reference

12 December 2020

Identification of a nuclear receptor for bile acids

1 reference

12 December 2020

Identification of a nuclear receptor that is activated by farnesol metabolites

1 reference

12 December 2020

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

1 reference

12 December 2020

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

1 reference

12 December 2020

X-ray structure of the orphan nuclear receptor RORbeta ligand-binding domain in the active conformation.

1 reference

12 December 2020

Redundant pathways for negative feedback regulation of bile acid production

1 reference

12 December 2020

Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase

1 reference

12 December 2020

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

1 reference

12 December 2020

Bile acid regulation of gene expression: roles of nuclear hormone receptors.

1 reference

12 December 2020

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

12 December 2020

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

12 December 2020

Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor

1 reference

12 December 2020

6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.

1 reference

12 December 2020

Bile acids: natural ligands for an orphan nuclear receptor

1 reference

12 December 2020

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

1 reference

12 December 2020

Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor

1 reference

12 December 2020

"Don't know much bile-ology"

1 reference

12 December 2020

Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors

1 reference

12 December 2020

Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries

1 reference

12 December 2020

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

1 reference

12 December 2020

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

1 reference

12 December 2020

A natural product that lowers cholesterol as an antagonist ligand for FXR.

1 reference

12 December 2020

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

1 reference

12 December 2020

Crystal structure of the human RXRalpha ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

1 reference

12 December 2020

Maximum-likelihood density modification

1 reference

12 December 2020

BAREing it all: the adoption of LXR and FXR and their roles in lipid homeostasis

1 reference

12 December 2020

SXR, a novel steroid and xenobiotic-sensing nuclear receptor

1 reference

12 December 2020

Identification of a chemical tool for the orphan nuclear receptor FXR.

1 reference

12 December 2020

Automated MAD and MIR structure solution

1 reference

12 December 2020

Preparation of selenomethionyl proteins for phase determination

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS1097-2765%2803%2900104-7

7 January 2021

inferred from DOI database lookup

Profile. K. C. Nicolaou

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Crossref

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7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/S1097-2765(03)00104-7

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3 November 2019

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3 November 2019

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