Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis (Q35867371)

10 August 2017

Antigen 85C inhibition restricts Mycobacterium tuberculosis growth through disruption of cord factor biosynthesis (English)

1 reference

Mycobacterium tuberculosis

10 August 2017

0 references

Markus Schade

7

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Martin Gengenbacher

Martin Gengenbacher

5

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Anne Diehl

Anne Diehl

4

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Hartmut Oschkinat

Hartmut Oschkinat

8

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Stefan Kaufmann

Stefan H E Kaufmann

12

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author name string

Thulasi Warrier

1

1 reference

10 August 2017

Marielle Tropis

2

1 reference

10 August 2017

Jim Werngren

3

1 reference

10 August 2017

Brigitte Schlegel

6

1 reference

10 August 2017

Mamadou Daffe

9

1 reference

10 August 2017

Sven Hoffner

10

1 reference

10 August 2017

Ali Nasser Eddine

11

1 reference

10 August 2017

language of work or name

English

0 references

publication date

30 January 2012

1 reference

Antimicrobial Agents and Chemotherapy

10 August 2017

1 reference

10 August 2017

56

1 reference

10 August 2017

4

1 reference

10 August 2017

1735-1743

1 reference

describes a project that uses

10 August 2017

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3318338/fullTextXML

inferred from PubMed Central ID database lookup

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The mycolyltransferase 85A, a putative drug target of Mycobacterium tuberculosis: development of a novel assay and quantification of glycolipid-status of the mycobacterial cell wall

11 July 2018

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Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

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11 July 2018

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A coupled assay measuring Mycobacterium tuberculosis antigen 85C enzymatic activity

11 July 2018

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11 July 2018

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Targeting the formation of the cell wall core of M. tuberculosis

11 July 2018

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Why is long-term therapy required to cure tuberculosis?

11 July 2018

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Who puts the tubercle in tuberculosis?

11 July 2018

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11 July 2018

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11 July 2018

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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

11 July 2018

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A mutant of Mycobacterium tuberculosis H37Rv that lacks expression of antigen 85A is attenuated in mice but retains vaccinogenic potential

11 July 2018

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Synthesis of trehalose-based compounds and their inhibitory activities against Mycobacterium smegmatis

11 July 2018

1 reference

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Mycobacterium tuberculosis antigen 85A and 85C structures confirm binding orientation and conserved substrate specificity

11 July 2018

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Tuberculosis: a problem with persistence

11 July 2018

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TB drug discovery: addressing issues of persistence and resistance

11 July 2018

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Resazurin microtiter assay plate testing of Mycobacterium tuberculosis susceptibilities to second-line drugs: rapid, simple, and inexpensive method

11 July 2018

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The secret lives of the pathogenic mycobacteria

11 July 2018

1 reference

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Resazurin microtiter assay plate: simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis.

11 July 2018

1 reference

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Evidence for a partial redundancy of the fibronectin-binding proteins for the transfer of mycoloyl residues onto the cell wall arabinogalactan termini of Mycobacterium tuberculosis

11 July 2018

1 reference

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Synthesis and biological evaluation of trehalose analogs as potential inhibitors of mycobacterial cell wall biosynthesis

11 July 2018

1 reference

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An interfacial mechanism and a class of inhibitors inferred from two crystal structures of the Mycobacterium tuberculosis 30 kDa major secretory protein (Antigen 85B), a mycolyl transferase

11 July 2018

1 reference

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A small-molecule nitroimidazopyran drug candidate for the treatment of tuberculosis

11 July 2018

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InhA, a target of the antituberculous drug isoniazid, is involved in a mycobacterial fatty acid elongation system, FAS-II

11 July 2018

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Crystal structure of the secreted form of antigen 85C reveals potential targets for mycobacterial drugs and vaccines

11 July 2018

1 reference

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Disruption of the genes encoding antigen 85A and antigen 85B of Mycobacterium tuberculosis H37Rv: effect on growth in culture and in macrophages

11 July 2018

1 reference

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Inactivation of the antigen 85C gene profoundly affects the mycolate content and alters the permeability of the Mycobacterium tuberculosis cell envelope

11 July 2018

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Role of the major antigen of Mycobacterium tuberculosis in cell wall biogenesis

11 July 2018

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inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

11 July 2018

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Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturation

11 July 2018

1 reference

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

11 July 2018

1 reference

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Effect of isoniazid on the in vivo mycolic acid synthesis, cell growth, and viability of Mycobacterium tuberculosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

Characterization of fibronectin-binding antigens released by Mycobacterium tuberculosis and Mycobacterium bovis BCG

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

Inhibition of synthesis of arabinogalactan by ethambutol in Mycobacterium smegmatis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

The genes coding for the antigen 85 complexes of Mycobacterium tuberculosis and Mycobacterium bovis BCG are members of a gene family: cloning, sequence determination, and genomic organization of the gene coding for antigen 85-C of M. tuberculosis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

Negative regulation by Ser/Thr phosphorylation of HadAB and HadBC dehydratases from Mycobacterium tuberculosis type II fatty acid synthase system

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

Evaluation of wild-type MIC distributions as a tool for determination of clinical breakpoints for Mycobacterium tuberculosis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

Characterization of the factor in L-cell conditioned medium capable of stimulating colony formation by mouse marrow cells in culture

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

XDR Tuberculosis — Implications for Global Public Health

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall

14 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318338

The outer parts of the mycobacterial envelope as permeability barriers

14 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22290959

12 December 2020

inferred from PubMed ID database lookup

Preparation of cell-wall fractions from mycobacteria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22290959

12 December 2020

inferred from PubMed ID database lookup

The M. tuberculosis antigen 85 complex and mycolyltransferase activity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22290959

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1128/AAC.05742-11

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22290959

1 reference