Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins (Q35849376)

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scientific article published on 24 November 2015

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English	Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins	scientific article published on 24 November 2015

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scholarly article

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Europe PubMed Central

10 August 2017

Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins (English)

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Europe PubMed Central

10 August 2017

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neurodegeneration

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Vincent Kam Wai Wong

2

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7 June 2020

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An-Guo Wu

1

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7 June 2020

Wu Zeng

3

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7 June 2020

Liang Liu

4

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7 June 2020

Betty Yuen-Kwan Law

5

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24 November 2015

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Scientific Reports

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7 June 2020

5

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7 June 2020

17199

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7 June 2020

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Creative Commons Attribution 4.0 International

24 November 2015

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April 2022 Public Data File from Crossref

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https://scigraph.springernature.com/pub.10.1038/srep17199

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UPLC-Q-TOF-MS(E) analysis of the constituents of Ding-Zhi-Xiao-Wan, a traditional Chinese antidepressant, in normal and depressive rats

1 reference

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11 July 2018

Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy.

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Proteostasis impairment in protein-misfolding and -aggregation diseases

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11 July 2018

Preclinical evidence of rapid-onset antidepressant-like effect in Radix Polygalae extract

1 reference

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11 July 2018

Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells

1 reference

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11 July 2018

A representative prescription for emotional disease, Ding-Zhi-Xiao-Wan restores 5-HT system deficit through interfering the synthesis and transshipment in chronic mild stress-induced depressive rats

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Protein aggregation and degradation mechanisms in neurodegenerative diseases

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Clionosterol and ethyl cholestan-22-enol isolated from the rhizome of Polygala tenuifolia inhibit phosphatidylinositol 3-kinase/Akt pathway

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α-Synuclein in Parkinson's disease

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Polygalasaponin F induces long-term potentiation in adult rat hippocampus via NMDA receptor activation

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Α-synuclein misfolding and Parkinson's disease

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Inflammatory and neurodegenerative pathways in depression: a new avenue for antidepressant development?

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Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells

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Ageing and neurodegenerative diseases

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Anxiolytic and sedative-hypnotic activities of polygalasaponins from Polygala tenuifolia in mice

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Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells

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A new A431/cell membrane chromatography and online high performance liquid chromatography/mass spectrometry method for screening epidermal growth factor receptor antagonists from Radix sophorae flavescentis.

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11 July 2018

Potential antidepressant properties of Radix Polygalae (Yuan Zhi).

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11 July 2018

Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4657008

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Formation of toxic oligomeric alpha-synuclein species in living cells

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Effects of tenuifolin extracted from radix polygalae on learning and memory: a behavioral and biochemical study on aged and amnesic mice

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Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila.

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Autophagy: process and function

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Studies on the constituents of Polygala japonica Houtt. I. Structures of polygalasaponins I-X

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Nine new triterpene saponins, polygalasaponins XXXIII--XLI from the roots of Polygala fallax Hemsl

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Five new triterpene saponins, polygalasaponins XXVIII-XXXII from the root of Polygala japonica Houtt

1 reference

https://pubmed.ncbi.nlm.nih.gov/26598009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polygalasaponins XLII-XLVI from roots of Polygala glomerata

1 reference

https://pubmed.ncbi.nlm.nih.gov/26598009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive binding between 4,4'-diphenylmethane-bis(methyl) carbamate and RAGE ligand MG-H1 on human umbilical vein endothelial cell by cell membrane chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/26598009

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based on heuristic

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Studies on the constituents of Polygala japonica HOUTT. II. Structures of polygalasaponins XI-XIX

1 reference

https://pubmed.ncbi.nlm.nih.gov/26598009

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Studies on the constituents of the root of Polygala tenuifolia Willdenow. II. On the structures of onjisaponins A, B and E.

1 reference

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https://opencitations.net/index/api/v1/citations/10.1248/CPB.30.810

Identifiers

10.1038/SREP17199

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598009%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26598009%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

1 reference

Europe PubMed Central

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7 June 2020

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