Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development (Q35848780)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813770%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Notch ligand delta-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21813770%20AND%20SRC:MED&resulttype=core&format=json

experimental autoimmune encephalomyelitis

9 February 2020

main subject

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author

Samia Khoury

7

1 reference

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9 February 2020

author name string

Ribal Bassil

1

1 reference

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9 February 2020

Bing Zhu

2

1 reference

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9 February 2020

Youmna Lahoud

3

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9 February 2020

Leonardo V Riella

4

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9 February 2020

Hideo Yagita

5

1 reference

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9 February 2020

Wassim Elyaman

6

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9 February 2020

language of work or name

English

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publication date

3 August 2011

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9 February 2020

published in

Journal of Immunology

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9 February 2020

volume

187

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9 February 2020

issue

5

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9 February 2020

page(s)

2322-2328

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Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity

9 February 2020

cites work

1 reference

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New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

11 July 2018

1 reference

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Differentiation of effector CD4 T cell populations (*)

11 July 2018

1 reference

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In vivo depletion of CD4+FOXP3+ Treg cells by the PC61 anti-CD25 monoclonal antibody is mediated by FcgammaRIII+ phagocytes

11 July 2018

1 reference

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Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes

11 July 2018

1 reference

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Amyloid precursor family proteins are expressed by thymic and lymph node stromal cells but are not required for lymphocyte development

11 July 2018

1 reference

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How are T(H)1 and T(H)2 effector cells made?

11 July 2018

1 reference

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Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade

11 July 2018

1 reference

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The different faces of Notch in T-helper-cell differentiation

11 July 2018

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TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4

11 July 2018

1 reference

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Notch ligand Delta-like4 inhibits the development of murine experimental allergic conjunctivitis.

11 July 2018

1 reference

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Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells

11 July 2018

1 reference

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Th2 differentiation is unaffected by Jagged2 expression on dendritic cells

11 July 2018

1 reference

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Notch1 signaling and regulatory T cell function

11 July 2018

1 reference

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Suppression of Th2 cell development by Notch ligands Delta1 and Delta4

11 July 2018

1 reference

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The origin and application of experimental autoimmune encephalomyelitis

11 July 2018

1 reference

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The dynamics of effector T cells and Foxp3+ regulatory T cells in the promotion and regulation of autoimmune encephalomyelitis

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells

11 July 2018

1 reference

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CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Nonredundant roles for Stat5a/b in directly regulating Foxp3

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Notch signalling: a simple pathway becomes complex

11 July 2018

1 reference

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CD4+CD25+ regulatory T cells limit the risk of autoimmune disease arising from T cell receptor crossreactivity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27 Kip1 degradation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

FOXP3 acts as a rheostat of the immune response

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis

11 July 2018

1 reference

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Dendritic-cell control of pathogen-driven T-cell polarization

11 July 2018

1 reference

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Cross-talk between the Notch and TGF-beta signaling pathways mediated by interaction of the Notch intracellular domain with Smad3

11 July 2018

1 reference

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Interleukin 2 signaling is required for CD4(+) regulatory T cell function

11 July 2018

1 reference

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Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex

11 July 2018

1 reference

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

11 July 2018

1 reference

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

11 July 2018

1 reference

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Structural conservation of Notch receptors and ligands

11 July 2018

1 reference

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Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

11 July 2018

1 reference

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

11 July 2018

1 reference

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Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease

11 July 2018

1 reference

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Active induction of experimental allergic encephalomyelitis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Regulation of experimental autoimmune encephalomyelitis by CD4+, CD25+ and CD8+ T cells: analysis using depleting antibodies

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311114

Regulation of T cell activation by Notch ligand, DLL4, promotes IL-17 production and Rorc activation

24 September 2018

1 reference

12 December 2020

Notch signaling in the immune system

1 reference

12 December 2020

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

1 reference

12 December 2020

Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis

1 reference

12 December 2020

IL-10 is involved in the suppression of experimental autoimmune encephalomyelitis by CD25+CD4+ regulatory T cells

1 reference

12 December 2020

Comment on "Cutting Edge: Anti-CD25 Monoclonal Antibody Injection Results in the Functional Inactivation, Not Depletion, of CD4+CD25+ T Regulatory Cells"

1 reference

12 December 2020

Comment on "Cutting edge: anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells"

1 reference

12 December 2020

Passive induction of experimental allergic encephalomyelitis

1 reference

12 December 2020

JAGGED1 and delta1 differentially regulate the outcome of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1100725

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30 July 2022

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Fatcat

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30 July 2022