New advances on the functions of epidermal growth factor receptor and ceramides in skin cell differentiation, disorders and cancers (Q35838744)

10 August 2017

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title

New advances on the functions of epidermal growth factor receptor and ceramides in skin cell differentiation, disorders and cancers (English)

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10 August 2017

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Mimeault M

1

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10 August 2017

Bonenfant D

series ordinal

2

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10 August 2017

Batra SK

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3

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10 August 2017

language of work or name

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1 July 2004

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Skin Pharmacology and Physiology

10 August 2017

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10 August 2017

17

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10 August 2017

4

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10 August 2017

153-166

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Epidermal lipids, barrier function, and desquamation

10 August 2017

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Barrier function of the skin: "la raison d'être" of the epidermis

21 January 2018

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Biochemical analysis of epidermal lipids

21 January 2018

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Cutaneous lipids: from physiology to the clinical

21 January 2018

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Ceramide and cholesterol composition of the skin of patients with atopic dermatitis.

21 January 2018

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The stratum corneum: structure and function in health and disease

21 January 2018

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Dandruff: a condition characterized by decreased levels of intercellular lipids in scalp stratum corneum and impaired barrier function

21 January 2018

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Deficiency of epidermal protein-bound omega-hydroxyceramides in atopic dermatitis

21 January 2018

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Sphingosylphosphorylcholine is upregulated in the stratum corneum of patients with atopic dermatitis

21 January 2018

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EGF upregulates, whereas TGF-beta downregulates, the hyaluronan synthases Has2 and Has3 in organotypic keratinocyte cultures: correlations with epidermal proliferation and differentiation

21 January 2018

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Flotillas of lipid rafts in transit amplifying cell-like keratinocytes

21 January 2018

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Differential expression of epidermal growth factor receptor in melanocytic tumours demonstrated by immunohistochemistry and mRNA in situ hybridization

21 January 2018

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Coexpression patterns of EGFR, HER2, HER3 and HER4 in non-melanoma skin cancer.

21 January 2018

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Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes

21 January 2018

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Regulation of epidermal growth factor receptor expression in human melanocytes

21 January 2018

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21 January 2018

Oncogenes in melanoma

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Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancer

21 January 2018

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21 January 2018

UV-induced skin damage

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New advances on structural and biological functions of ceramide in apoptotic/necrotic cell death and cancer

21 January 2018

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Cholesterol-rich plasma membrane domains (lipid rafts) in keratinocytes: importance in the baseline and UVA-induced generation of reactive oxygen species

21 January 2018

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Caveolin-1 phosphorylation in human squamous and epidermoid carcinoma cells: dependence on ErbB1 expression and Src activation

21 January 2018

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Apoptosis signal-regulating kinase 1 (ASK1) is an intracellular inducer of keratinocyte differentiation

21 January 2018

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Terminal differentiation of human epidermal keratinocytes involves mitochondria- and caspase-dependent cell death pathway.

21 January 2018

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Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing

21 January 2018

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Localization of ceramide and glucosylceramide in human epidermis by immunogold electron microscopy.

21 January 2018

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Sphingolipid metabolism during epidermal barrier development in mice

21 January 2018

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C2-ceramide induces apoptosis in a human squamous cell carcinoma cell line

21 January 2018

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Human epidermal glucosylceramides are major precursors of stratum corneum ceramides

21 January 2018

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Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function

21 January 2018

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A comparative review of cutaneous pH.

21 January 2018

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NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging

21 January 2018

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Structure of the skin barrier and its modulation by vesicular formulations

21 January 2018

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Ceramides and the stratum corneum: structure, function, and new methods to promote repair

21 January 2018

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FTIR spectroscopic analyses of the temperature and pH influences on stratum corneum lipid phase behaviors and interactions

21 January 2018

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Characterization of the stratum corneum lipid matrix using fluorescence spectroscopy

21 January 2018

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Models of stratum corneum intercellular membranes: the sphingolipid headgroup is a determinant of phase behavior in mixed lipid dispersions

21 January 2018

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A model membrane approach to the epidermal permeability barrier.

21 January 2018

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X-ray diffraction analysis of isolated skin lipids: reconstitution of intercellular lipid domains.

21 January 2018

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Influence of different ceramides on the structure of in vitro model lipid systems of the stratum corneum lipid matrix

21 January 2018

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Calorimetric and electron spin resonance examination of lipid phase transitions in human stratum corneum: molecular basis for normal cohesion and abnormal desquamation in recessive X-linked ichthyosis

21 January 2018

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The aged epidermal permeability barrier: basis for functional abnormalities

21 January 2018

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Sphingolipid signaling in epidermal homeostasis. Current knowledge and new therapeutic approaches in dermatology

21 January 2018

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Functional consequences of cutaneous lipid perturbation

21 January 2018

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The skin of atopic dermatitis patients contains a novel enzyme, glucosylceramide sphingomyelin deacylase, which cleaves the N-acyl linkage of sphingomyelin and glucosylceramide

21 January 2018

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Blockade of the EGF receptor induces a deranged chemokine expression in keratinocytes leading to enhanced skin inflammation

21 January 2018

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Induction of disease-associated keratin 16 gene expression by epidermal growth factor is regulated through cooperation of transcription factors Sp1 and c-Jun

21 January 2018

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High-expression of sphingomyelin deacylase is an important determinant of ceramide deficiency leading to barrier disruption in atopic dermatitis

21 January 2018

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Nitric oxide-peroxynitrite-poly(ADP-ribose) polymerase pathway in the skin

21 January 2018

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Variable expression of apoptotic phenotype in keratinocytes treated with ultraviolet radiation, ceramide, or suspended in semisolid methylcellulose.

21 January 2018

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Decreased levels of sphingosine, a natural antimicrobial agent, may be associated with vulnerability of the stratum corneum from patients with atopic dermatitis to colonization by Staphylococcus aureus

21 January 2018

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Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides

21 January 2018

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Effect of a lipid-rich emollient containing ceramide 3 in experimentally induced skin barrier dysfunction

21 January 2018

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Detergent-induced epidermal barrier dysfunction and its prevention

21 January 2018

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Metabolic approaches to enhance transdermal drug delivery. 1. Effect of lipid synthesis inhibitors.

21 January 2018

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New strategy for antedrug application: development of metalloproteinase inhibitors as antipsoriatic drugs

21 January 2018

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Evaluation of efficacy of a skin lipid mixture in patients with irritant contact dermatitis, allergic contact dermatitis or atopic dermatitis: a multicenter study

21 January 2018

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Treatment of atopic blepharitis by controlling eyelid skin water retention ability with ceramide gel application

21 January 2018

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Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis: changes in barrier function provide a sensitive indicator of disease activity

21 January 2018

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Skin-identical lipids versus petrolatum in the treatment of tape-stripped and detergent-perturbed human skin

21 January 2018

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Optimization of physiological lipid mixtures for barrier repair

21 January 2018

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Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids

21 January 2018

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L-Serine and glycine based ceramide analogues as transdermal permeation enhancers: polar head size and hydrogen bonding

21 January 2018

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Epidemiology of cutaneous melanoma and non-melanoma skin cancer in Schleswig-Holstein, Germany: incidence, clinical subtypes, tumour stages and localization (epidemiology of skin cancer).

21 January 2018

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Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes

21 January 2018

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Cellular and molecular biology of human melanoma

21 January 2018

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A comparative review of melanocytic neoplasms

21 January 2018

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Tumor-stroma interactions directing phenotype and progression of epithelial skin tumor cells

21 January 2018

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Dermatological aspects of angiogenesis

21 January 2018

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c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

21 January 2018

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The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development

21 January 2018

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Functional roles of Akt signaling in mouse skin tumorigenesis.

21 January 2018

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Inhibition of the epidermal growth factor receptor suppresses telomerase activity in HSC-1 human cutaneous squamous cell carcinoma cells

21 January 2018

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Epidermal growth factor receptor overexpression and genetic aberrations in metastatic squamous-cell carcinoma of the skin.

21 January 2018

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Constitutive expression of erbB2 in epidermis of transgenic mice results in epidermal hyperproliferation and spontaneous skin tumor development

21 January 2018

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New advances on prostate carcinogenesis and therapies: involvement of EGF-EGFR transduction system

21 January 2018

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Enhancement of susceptibility to diverse skin tumor promoters by activation of the insulin-like growth factor-1 receptor in the epidermis of transgenic mice

21 January 2018

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The phosphotidyl inositol 3-kinase/Akt signal pathway is involved in interleukin-6-mediated Mcl-1 upregulation and anti-apoptosis activity in basal cell carcinoma cells.

21 January 2018

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Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

21 January 2018

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Angiogenesis--anti-angiogenesis. Significance for tumor growth and metastasis

21 January 2018

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Photodynamic therapy for the treatment of skin disease

21 January 2018

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Combinations of anticancer drugs and immunotherapy

21 January 2018

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Dendritic cell-based cancer immunotherapy.

21 January 2018

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Interferon as adjuvant treatment for melanoma

21 January 2018

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Adjuvant therapy for high-risk primary and resected metastatic melanoma

21 January 2018

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Skin cancer chemopreventive effects of a flavonoid antioxidant silymarin are mediated via impairment of receptor tyrosine kinase signaling and perturbation in cell cycle progression.

21 January 2018

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In vitro and in vivo inhibition of epidermal growth factor receptor-tyrosine kinase pathway by photodynamic therapy

21 January 2018

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Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors

21 January 2018

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Flavonoid antioxidant silymarin and skin cancer

21 January 2018

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Inhibition of ultraviolet light-induced oxidative events in the skin and internal organs of hairless mice by isoflavone genistein

21 January 2018

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Differential responses of skin cancer-chemopreventive agents silibinin, quercetin, and epigallocatechin 3-gallate on mitogenic signaling and cell cycle regulators in human epidermoid carcinoma A431 cells

21 January 2018

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Pharmacodynamic studies of the epidermal growth factor receptor inhibitor ZD1839 in skin from cancer patients: histopathologic and molecular consequences of receptor inhibition

21 January 2018

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Effects of C2-ceramide on the Malme-3M melanoma cell line

21 January 2018

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Bcl-2 overexpression prevents apoptosis induced by ceramidase inhibitors in malignant melanoma and HaCaT keratinocytes.

21 January 2018

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Transfection of glucosylceramide synthase antisense inhibits mouse melanoma formation.

21 January 2018

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Photodynamic therapy of skin cancers: sensitizers, clinical studies and future directives

21 January 2018

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Temozolomide in combination with interferon alpha-2b in patients with metastatic melanoma: a phase I dose-escalation study

21 January 2018

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p53 alone or in combination with antisense cyclin D1 induces apoptosis and reduces tumor size in human melanoma

21 January 2018

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Brain metastases following interleukin-2 plus interferon-alpha-2a therapy: a follow-up study in 94 stage IV melanoma patients.

21 January 2018

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Randomized phase II study of temozolomide given every 8 hours or daily with either interferon alfa-2b or thalidomide in metastatic malignant melanoma

21 January 2018

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Temozolomide followed by combined immunotherapy with GM-CSF, low-dose IL2 and IFN alpha in patients with metastatic melanoma

21 January 2018

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Experiences with therapy of stage IV metastatic malignant melanoma with "Legha Protocol" polychemoimmunotherapy

21 January 2018

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Priming of T cells with Ad-transduced DC followed by expansion with peptide-pulsed DC significantly enhances the induction of tumor-specific CD8+ T cells: implications for an efficient vaccination strategy

21 January 2018

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The novel retinoid AHPN/CD437 induces a rapid but incomplete apoptotic response in human myeloma cells

21 January 2018

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Interleukin-1-stimulated Secretion of Interleukin-8 and Growth-related Oncogene-α Demonstrates Greatly Enhanced Keratinocyte Growth in Human Raft Cultured Epidermis

21 January 2018

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Synergy between tumor immunotherapy and antiangiogenic therapy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000078818

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10 August 2017

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