Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation (Q35835238)

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scientific article published in March 1995

Language	Label	Description	Also known as
English	Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation	scientific article published in March 1995

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scholarly article

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27 October 2019

Direct interaction of the hepatitis B virus HBx protein with p53 leads to inhibition by HBx of p53 response element-directed transactivation (English)

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27 October 2019

Hepatitis B virus

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based on heuristic

inferred from title

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based on heuristic

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author name string

Truant R

1

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27 October 2019

Antunovic J

2

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27 October 2019

Greenblatt J

3

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27 October 2019

Prives C

4

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27 October 2019

Cromlish JA

5

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27 October 2019

language of work or name

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publication date

1 March 1995

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27 October 2019

Journal of Virology

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27 October 2019

69

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27 October 2019

1851-1859

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27 October 2019

3

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27 October 2019

p53 binds to the TATA-binding protein-TATA complex.

1 reference

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11 July 2018

The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

1 reference

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11 July 2018

Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif

1 reference

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11 July 2018

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

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11 July 2018

The p53 protein is an unusually shaped tetramer that binds directly to DNA.

1 reference

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11 July 2018

Hepatitis B virus transactivator HBx uses a tumour promoter signalling pathway

1 reference

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11 July 2018

Human p53 binds DNA as a protein homodimer but monomeric variants retain full transcription transactivation activity

1 reference

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11 July 2018

Cooperative DNA binding of p53 with TFIID (TBP): a possible mechanism for transcriptional activation

1 reference

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11 July 2018

The tumor suppressor genes

1 reference

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11 July 2018

EBNA-5, an Epstein-Barr virus-encoded nuclear antigen, binds to the retinoblastoma and p53 proteins.

1 reference

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11 July 2018

Tumor-suppressor p53 gene in hepatitis C and B virus-associated human hepatocellular carcinoma

1 reference

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11 July 2018

SV40 T antigen abrogates p53-mediated transcriptional activity.

1 reference

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11 July 2018

Transactivation by hepatitis B virus X protein is promiscuous and dependent on mitogen-activated cellular serine/threonine kinases.

1 reference

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11 July 2018

General initiation factors for RNA polymerase II.

1 reference

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11 July 2018

Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes

1 reference

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11 July 2018

Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

1 reference

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11 July 2018

Genetic heterogeneity of hepatocellular carcinoma

1 reference

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11 July 2018

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.

1 reference

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11 July 2018

WAF1, a potential mediator of p53 tumor suppression

1 reference

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11 July 2018

The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53

1 reference

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11 July 2018

Molecular events in the pathogenesis of hepadnavirus-associated hepatocellular carcinoma

1 reference

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11 July 2018

High-level expression of hepatitis B virus HBx gene and hepatocarcinogenesis in transgenic mice

1 reference

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11 July 2018

Hepatitis B virus X protein inhibits p53 sequence-specific DNA binding, transcriptional activity, and association with transcription factor ERCC3

1 reference

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11 July 2018

Sequence-specific transcriptional activation is essential for growth suppression by p53.

1 reference

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11 July 2018

Identification of a p53 binding site in the human retinoblastoma susceptibility gene promoter.

1 reference

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11 July 2018

Transactivation of human hepatitis B virus X protein, HBx, operates through a mechanism distinct from protein kinase C and okadaic acid activation pathways

1 reference

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11 July 2018

Functional and physical interaction between p53 and BZLF1: implications for Epstein-Barr virus latency

1 reference

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11 July 2018

Infrequent mutation of p53 gene in hepatitis B virus positive primary hepatocellular carcinomas

1 reference

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11 July 2018

Tumor suppressor genes, growth factor genes, and oncogenes in hepatitis B virus-associated hepatocellular carcinoma

1 reference

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11 July 2018

Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53

1 reference

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11 July 2018

Induction of the DNA-binding activity of c-jun/c-fos heterodimers by the hepatitis B virus transactivator pX

1 reference

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11 July 2018

Molecular weight analysis of oligopeptides by electrophoresis in polyacrylamide gel with sodium dodecyl sulfate.

1 reference

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11 July 2018

Interaction of a gene-specific transcription factor with the adenovirus major late promoter upstream of the TATA box region.

1 reference

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11 July 2018

Primary structure polymorphism at amino acid residue 72 of human p53.

1 reference

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11 July 2018

Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes

1 reference

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11 July 2018

DNA binding properties of murine p53.

1 reference

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11 July 2018

The adenovirus tripartite leader may eliminate the requirement for cap-binding protein complex during translation initiation

1 reference

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11 July 2018

Transcriptional repression of eukaryotic promoters

1 reference

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11 July 2018

Functional domains and upstream activation properties of cloned human TATA binding protein

1 reference

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11 July 2018

Synergistic activation of transcription by the human estrogen receptor bound to tandem responsive elements

1 reference

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11 July 2018

Factors involved in specific transcription by mammalian RNA polymerase II: identification of general transcription factor TFIIG.

1 reference

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11 July 2018

Wild-type, but not mutant, human p53 proteins inhibit the replication activities of simian virus 40 large tumor antigen

1 reference

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11 July 2018

Transactivation by the hepatitis B virus X protein depends on AP-2 and other transcription factors

1 reference

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11 July 2018

Domains required for in vitro association between the cellular p53 and the adenovirus 2 E1B 55K proteins.

1 reference

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11 July 2018

Presence of a potent transcription activating sequence in the p53 protein

1 reference

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11 July 2018

HBx gene of hepatitis B virus induces liver cancer in transgenic mice

1 reference

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11 July 2018

Protein synthesis required to anchor a mutant p53 protein which is temperature-sensitive for nuclear transport

1 reference

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11 July 2018

Evidence for a factor required for transcriptional stimulation by the chimeric acidic activator GAL-VP16 in HeLa cell extracts

1 reference

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11 July 2018

HBV X protein alters the DNA binding specificity of CREB and ATF-2 by protein-protein interactions

1 reference

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11 July 2018

Detection of p53 in primary lung tumors and nonsmall cell lung carcinoma cell lines

1 reference

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11 July 2018

Formation of stable p53 homotetramers and multiples of tetramers

1 reference

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11 July 2018

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

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11 July 2018

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1 reference

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11 July 2018

p53 function and dysfunction

1 reference

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11 July 2018

Regulation of the specific DNA binding function of p53

1 reference

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11 July 2018

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

1 reference

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11 July 2018

Alternate translation initiation on hepatitis B virus X mRNA produces multiple polypeptides that differentially transactivate class II and III promoters

1 reference

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11 July 2018

Hepatitis B virus X protein activates transcription factor NF-kappa B without a requirement for protein kinase C

1 reference

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11 July 2018

Definition of a consensus binding site for p53

1 reference

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11 July 2018

Absence of HeLa cell contamination in 169 cell lines derived from human tumors

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11 July 2018

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis

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11 July 2018

Viral transactivation. Pleiotropy and henchman X.

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24 September 2018

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

1 reference

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24 September 2018

Interaction of hepatitis B virus X protein with a serine protease, tryptase TL2 as an inhibitor.

1 reference

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24 September 2018

Human hepatitis virus X gene encodes a regulatory domain that represses transactivation of X protein.

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24 September 2018

The 17 kDa HBx protein encoded by hepatitis B virus interacts with the activation domains of Oct-1, and functions as a coactivator in the activation and repression of a human U6 promoter.

1 reference

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24 September 2018

An amino-terminal fragment of GAL4 binds DNA as a dimer

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24 September 2018

Nuclear localization is essential for the activity of p53 protein

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15 November 2018

Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein

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12 December 2020

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The p53 tumor suppressor protein: meeting review

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12 December 2020

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Hepatitis B x antigen and p53 are associated in vitro and in liver tissues from patients with primary hepatocellular carcinoma

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12 December 2020

based on heuristic

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The value of hepatitis B x antigen as a prognostic marker in the development of hepatocellular carcinoma

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12 December 2020

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From hepatitis to hepatoma: lessons from type B viral hepatitis

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12 December 2020

based on heuristic

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The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of p53 quaternary structure in relation to sequence-specific DNA binding

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of action of an acidic transcriptional activator in vitro

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wild-type p53 activates transcription in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/7853526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Negative effect of the transcriptional activator GAL4

1 reference

https://pubmed.ncbi.nlm.nih.gov/7853526

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Primer extension analysis of RNA

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Luciferase reporter gene vectors for analysis of promoters and enhancers

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12 December 2020

based on heuristic

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Identifiers

1 reference

Europe PubMed Central

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27 October 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7853526%20AND%20SRC:MED&resulttype=core&format=json

27 October 2019

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