The G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila. (Q35808842)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17483466%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

title

The G protein-coupled receptor regulatory kinase GPRK2 participates in Hedgehog signaling in Drosophila (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17483466%20AND%20SRC:MED&resulttype=core&format=json

G protein-coupled receptor

30 December 2019

main subject

Drosophila

0 references

0 references

G protein-coupled receptor kinase 2 Dmel_CG17998

1 reference

GOA release 2020-03-11

author

Cristina Molnar

1

1 reference

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30 December 2019

author name string

Helena Holguin

2

1 reference

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30 December 2019

Federico Mayor

3

1 reference

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30 December 2019

Ana Ruiz-Gomez

4

1 reference

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30 December 2019

Jose F de Celis

5

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30 December 2019

language of work or name

English

0 references

publication date

1 May 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17483466%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

30 December 2019

published in

1 reference

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30 December 2019

volume

104

1 reference

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30 December 2019

issue

19

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30 December 2019

page(s)

7963-7968

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Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2

30 December 2019

cites work

1 reference

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Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

11 July 2018

1 reference

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Transduction of receptor signals by beta-arrestins

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Communicating with Hedgehogs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Hedgehog signalling activity of Smoothened requires phosphorylation by protein kinase A and casein kinase I.

11 July 2018

1 reference

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FlyBase: genes and gene models

11 July 2018

1 reference

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Extensive phosphorylation of Smoothened in Hedgehog pathway activation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

The Hedgehog response network: sensors, switches, and routers

11 July 2018

1 reference

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Regulation of spalt expression in the Drosophila wing blade in response to the Decapentaplegic signaling pathway

11 July 2018

1 reference

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Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in beta-tubulin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Regulation of G protein-coupled receptor kinases and arrestins during receptor desensitization

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Down-regulation of the alpha-2C adrenergic receptor: involvement of a serine/threonine motif in the third cytoplasmic loop

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Expression of the blistered/DSRF gene is controlled by different morphogens during Drosophila trachea and wing development

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

The Drosophila G-protein-coupled receptor kinase homologue Gprk2 is required for egg morphogenesis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Expression and function of decapentaplegic and thick veins during the differentiation of the veins in the Drosophila wing.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

araucan and caupolican provide a link between compartment subdivisions and patterning of sensory organs and veins in the Drosophila wing.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Dual roles for patched in sequestering and transducing Hedgehog

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila

11 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702374104

Gprk2 controls cAMP levels in Drosophila development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702374104

Smoothened translates Hedgehog levels into distinct responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702374104

Araucan and caupolican, two members of the novel iroquois complex, encode homeoproteins that control proneural and vein-forming genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0702374104

Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Connecting Hh, Dpp and EGF signalling in patterning of the Drosophila wing; the pivotal role of collier/knot in the AP organiser.

25 September 2018

1 reference

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Regulation of the spalt/spalt-related gene complex and its function during sensory organ development in the Drosophila thorax.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

Feed-back mechanisms affecting Notch activation at the dorsoventral boundary in the Drosophila wing.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1876555

25 September 2018

Identifiers

DOI

10.1073/PNAS.0702374104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17483466%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

0 references

1 reference

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30 December 2019

PubMed publication ID

17483466

1 reference