The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes (Q35804133)

10 August 2017

1 reference

title

The interleukin (IL)-2 family cytokines: survival and proliferation signaling pathways in T lymphocytes (English)

1 reference

10 August 2017

Marta Benczik

1

1 reference

PubMed ID

15195693

10 August 2017

Sarah L Gaffen

series ordinal

2

1 reference

10 August 2017

1 May 2004

1 reference

Immunological Investigations

10 August 2017

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10 August 2017

33

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10 August 2017

2

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10 August 2017

109-142

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Role of interleukin-7 in T-cell development from hematopoietic stem cells

10 August 2017

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Reconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

PI 3-K and T-cell activation: limitations of T-leukemic cell lines as signaling models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Bcl-2 targets protein phosphatase 1 alpha to Bad.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Regulation of GLUT1 gene transcription by the serine/threonine kinase Akt1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Heteromerization of the c Chain with the Interleukin-9 Receptor Subunit Leads to STAT Activation and Prevention of Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Selected glimpses into the activation and function of Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Growth factors can enhance lymphocyte survival without committing the cell to undergo cell division

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Ten years of protein kinase B signalling: a hard Akt to follow

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphatidylinositol 3-kinase is essential for the proliferation of lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cell cycle and death control: long live Forkheads

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The phosphoinositide 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Protein kinase B (Akt) regulation and function in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

PI 3-kinases and PTEN: how opposites chemoattract

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Role of PI3-kinase-dependent Bad phosphorylation and altered transcription in cytokine-mediated neutrophil survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukin-7 induces T cell proliferation in the absence of Erk/MAP kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

T cell proliferation in response to interleukins 2 and 7 requires p38MAP kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Distinct roles for STAT1, STAT3, and STAT5 in differentiation gene induction and apoptosis inhibition by interleukin-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Role of insulin receptor substrate-2 in interleukin-9-dependent proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

MAP kinase activation by interleukin-9 in lymphoid and mast cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Pten is essential for embryonic development and tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Forkhead transcription factor FKHR-L1 modulates cytokine-dependent transcriptional regulation of p27(KIP1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Akt maintains cell size and survival by increasing mTOR-dependent nutrient uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphoinositide 3-kinase in immunological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

21 January 2018

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Impaired B cell development and proliferation in absence of phosphoinositide 3-kinase p85alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Functional dissection of the cytoplasmic subregions of the IL-2 receptor betac chain in primary lymphocyte populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Signaling by type I and II cytokine receptors: ten years after

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Signaling domains of the interleukin 2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Regulation of translation initiation by FRAP/mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cross-talk between Akt, p53 and Mdm2: possible implications for the regulation of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

An interleukin-4-induced transcription factor: IL-4 Stat

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The role of SHIP in growth factor induced signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Janus kinases in cytokine signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Regulation of Akt-dependent cell survival by Syk and Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The p85 regulatory subunit controls sequential activation of phosphoinositide 3-kinase by Tyr kinases and Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphorylation and activation of the Jak-3 Janus kinase in response to interleukin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukins 2, 4, 7, and 15 stimulate tyrosine phosphorylation of insulin receptor substrates 1 and 2 in T cells. Potential role of JAK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Induction of NF-kappaB by the Akt/PKB kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The Src-family kinase, Fyn, regulates the activation of phosphatidylinositol 3-kinase in an interleukin 2-responsive T cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Death and Baxes: mechanisms of lymphotrophic cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Activation of phosphatidylinositol 3-kinase is sufficient for cell cycle entry and promotes cellular changes characteristic of oncogenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Human interleukin-4 receptor signaling requires sequences contained within two cytoplasmic regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The role of PI3K in immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Lipid phosphatases in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The stress-activated protein kinase subfamily of c-Jun kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Elf-1 and Stat5 bind to a critical element in a new enhancer of the human interleukin-2 receptor alpha gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Jaks and STATs: biological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Anti-apoptotic signaling by the interleukin-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (gamma c) receptor subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

JAK/STAT signaling by cytokine receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Regulation of the immune response by SHIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Functional cooperation of the interleukin-2 receptor beta chain and Jak1 in phosphatidylinositol 3-kinase recruitment and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

IL-2 signaling: recruitment and activation of multiple protein tyrosine kinases by the components of the IL-2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Pyk2 is a downstream mediator of the IL-2 receptor-coupled Jak signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Glycogen synthase kinase-3 inhibits the DNA binding activity of NFATc

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cytoplasmic domains of the interleukin-2 receptor beta and gamma chains mediate the signal for T-cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The protein kinase B/Akt signalling pathway in human malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

PI3K in lymphocyte development, differentiation and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Introduction: multifaceted roles of lipids and their catabolites in immune cell signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cytokine and cytokine receptor pleiotropy and redundancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cloning of murine Stat6 and human Stat6, Stat proteins that are tyrosine phosphorylated in responses to IL-4 and IL-3 but are not required for mitogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

IL-7 enhances the survival and maintains the size of naive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Aiolos transcription factor controls cell death in T cells by regulating Bcl-2 expression and its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

IL-7 inhibits dexamethasone-induced apoptosis via Akt/PKB in mature, peripheral T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Tec family kinases in lymphocyte signaling and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Mutational analysis of a critical signaling domain of the human interleukin 4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

3'-phosphoinositide-dependent kinase-1 (PDK-1) in PI 3-kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Xid-like immunodeficiency in mice with disruption of the p85alpha subunit of phosphoinositide 3-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Tec tyrosine kinase links the cytokine receptors to PI-3 kinase probably through JAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cellular signaling: pivoting around PDK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphoinositide 3-kinases: a conserved family of signal transducers

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukin 4 (IL-4) or IL-7 prevents the death of resting T cells: stat6 is probably not required for the effect of IL-4

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Cytokine-induced survival of activated T cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukin‐7 induces the association of phosphatidylinositol 3‐kinase with the α chain of the interleukin‐7 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The antiapoptotic gene mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through a transcription factor complex containing CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Phosphoinositide 3-kinases in T lymphocyte activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Regulation of phospholipase C gamma isoforms in haematopoietic cells: why one, not the other?

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Specificity of interleukin-2 receptor gamma chain superfamily cytokines is mediated by insulin receptor substrate-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Interleukin-9 induces tyrosine phosphorylation of insulin receptor substrate-1 via JAK tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Molecular characterization of specific interactions between SHP-2 phosphatase and JAK tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

21 January 2018

1 reference

https://api.crossref.org/works/10.1081%2FIMM-120030732

21 January 2018

Identifiers

DOI

10.1081/IMM-120030732

1 reference

10 August 2017

1 reference

PubMed ID

15195693