Epigenetic gene silencing by Runx proteins (Q35779768)

10 August 2017

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title

Epigenetic gene silencing by Runx proteins (English)

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10 August 2017

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2

Dan R Littman

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10 August 2017

Ichiro Taniuchi

1

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PubMed ID

15156191

10 August 2017

language of work or name

English

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publication date

1 May 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

24

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10 August 2017

4341-4345

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1207671

10 August 2017

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Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

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SUV39H1 interacts with AML1 and abrogates AML1 transactivity. AML1 is methylated in vivo

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Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

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Identification and characterization of a human CD4 silencer

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Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression.

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Heterochromatin protein 1 modifies mammalian PEV in a dose- and chromosomal-context-dependent manner

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Variegated expression of CD8 alpha resulting from in situ deletion of regulatory sequences.

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Sustained loss of a neoplastic phenotype by brief inactivation of MYC

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Translating the Histone Code

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment.

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Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly

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Rb targets histone H3 methylation and HP1 to promoters

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Expression of the Runt domain-encoding PEBP2 alpha genes in T cells during thymic development

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A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

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A transcriptional silencer controls the developmental expression of the CD4 gene.

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Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

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Evidence for distinct CD4 silencer functions at different stages of thymocyte differentiation.

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Positive selection of immature alpha beta T cells

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Beyond the nucleosome: epigenetic aspects of position-effect variegation in Drosophila.

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Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207671

1 reference

10 August 2017

1 reference

PubMed ID

15156191