Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity (Q35693984)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22144677%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity (English)

1 reference

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17 January 2020

0 references

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8

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17 January 2020

author name string

Tiangang Li

1

1 reference

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17 January 2020

Jessica M Francl

2

1 reference

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17 January 2020

Shannon Boehme

3

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17 January 2020

Adrian Ochoa

4

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17 January 2020

Youcai Zhang

5

1 reference

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17 January 2020

Curtis D Klaassen

6

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17 January 2020

Sandra K Erickson

7

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17 January 2020

language of work or name

English

0 references

publication date

5 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22144677%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 January 2020

published in

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17 January 2020

volume

287

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17 January 2020

page(s)

1861-1873

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17 January 2020

issue

3

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FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway

17 January 2020

cites work

1 reference

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Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

27 July 2018

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Diurnal variations of mouse plasma and hepatic bile acid concentrations as well as expression of biosynthetic enzymes and transporters

27 July 2018

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Overexpression of cholesterol 7α-hydroxylase promotes hepatic bile acid synthesis and secretion and maintains cholesterol homeostasis

27 July 2018

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Epigenetic phenomena linked to diabetic complications.

27 July 2018

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Effects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice

27 July 2018

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Transgenic expression of cholesterol 7alpha-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice

27 July 2018

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Epigenetic mechanisms in the development of type 2 diabetes

27 July 2018

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TGR5-mediated bile acid sensing controls glucose homeostasis

27 July 2018

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Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

27 July 2018

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Role of bile acids and bile acid receptors in metabolic regulation

27 July 2018

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Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression

27 July 2018

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Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

27 July 2018

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Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha

27 July 2018

1 reference

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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

27 July 2018

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Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis

27 July 2018

1 reference

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Bile acids lower triglyceride levels via a pathway involving FXR, SHP, and SREBP-1c

27 July 2018

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PGC-1α Activates CYP7A1 and Bile Acid Biosynthesis

27 July 2018

1 reference

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The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

27 July 2018

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A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis

27 July 2018

1 reference

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Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions

27 July 2018

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Regulation of cholesterol 7 alpha-hydroxylase in the liver. Purification of cholesterol 7 alpha-hydroxylase and the immunochemical evidence for the induction of cholesterol 7 alpha-hydroxylase by cholestyramine and circadian rhythm

27 July 2018

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Effects of diabetes mellitus on cholesterol metabolism in man.

27 July 2018

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FGF19 as a postprandial, insulin-independent activator of hepatic protein and glycogen synthesis

27 July 2018

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Glucose stimulates cholesterol 7alpha-hydroxylase gene transcription in human hepatocytes

25 September 2018

1 reference

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ATP-citrate lyase links cellular metabolism to histone acetylation

25 September 2018

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A glycolytic burst drives glucose induction of global histone acetylation by picNuA4 and SAGA.

25 September 2018

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Bile acids: regulation of synthesis

25 September 2018

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A novel role of transforming growth factor beta1 in transcriptional repression of human cholesterol 7alpha-hydroxylase gene

25 September 2018

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Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.

25 September 2018

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Insulin regulation of cholesterol 7alpha-hydroxylase expression in human hepatocytes: roles of forkhead box O1 and sterol regulatory element-binding protein 1c.

25 September 2018

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Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis.

25 September 2018

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

25 September 2018

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Cholic acid as key regulator of cholesterol synthesis, intestinal absorption and hepatic storage in mice.

25 September 2018

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Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription.

25 September 2018

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Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).

25 September 2018

1 reference

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Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

25 September 2018

1 reference

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Cholesterol 7 alpha-hydroxylase of rat liver: an insulin sensitive enzyme

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22144677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

46 Reversed-phase high-performance liquid chromatography assay of cholesterol 7α-hydroxylase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22144677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22144677

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.305789

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22144677%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22144677%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference