Protein kinase Czeta (PKCzeta) regulates ocular inflammation and apoptosis in endotoxin-induced uveitis (EIU): signaling molecules involved in EIU resolution by PKCzeta inhibitor and interleukin-13. (Q35691602)

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scientific article published on April 2007

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English	Protein kinase Czeta (PKCzeta) regulates ocular inflammation and apoptosis in endotoxin-induced uveitis (EIU): signaling molecules involved in EIU resolution by PKCzeta inhibitor and interleukin-13.	scientific article published on April 2007

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28 December 2019

Protein kinase Czeta (PKCzeta) regulates ocular inflammation and apoptosis in endotoxin-induced uveitis (EIU): signaling molecules involved in EIU resolution by PKCzeta inhibitor and interleukin-13 (English)

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Marie-Christine Naud

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Marie-Christine Naud

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Yvonne de Kozak

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Yvonne de Kozak

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Boubaker Omri

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Brigitte Thillaye-Goldenberg

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Patricia Crisanti

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1 April 2007

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The American Journal of Pathology

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1241-1257

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28 December 2019

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28 December 2019

The role of PKCzeta in NMDA-induced retinal ganglion cell death: prevention by aspirin

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Leukocyte diapedesis in vivo induces transient loss of tight junction protein at the blood-retina barrier.

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Aspirin prevention of NMDA-induced neuronal death by direct protein kinase Czeta inhibition

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BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophages

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The role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU).

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Inflammatory resolution: new opportunities for drug discovery

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Innate recognition of lipopolysaccharide by Toll-like receptor 4-MD-2.

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IL-10-inducible Bcl-3 negatively regulates LPS-induced TNF-alpha production in macrophages

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Essential role of RelA Ser311 phosphorylation by zetaPKC in NF-kappaB transcriptional activation

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12 July 2018

Uveitis: a global perspective

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12 July 2018

Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions

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12 July 2018

Visualization of Cell Death In Vivo during Murine Endotoxin-Induced Uveitis

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12 July 2018

NF-kappaB regulation in the immune system

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12 July 2018

NFkappaB-dependent signaling pathways

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12 July 2018

Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis

1 reference

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12 July 2018

NF-kappaB at the crossroads of life and death

1 reference

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12 July 2018

Inhibitory effects of pyrrolidine dithiocarbamate on endotoxin-induced uveitis in Lewis rats

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12 July 2018

Neutrophil accumulation correlates with type IV collagenase/gelatinase activity in endotoxin induced uveitis

1 reference

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12 July 2018

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

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12 July 2018

NF-kappa B-inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-kappa B1 residence

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12 July 2018

The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters

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12 July 2018

Apoptosis is a prominent feature of acute anterior uveitis in the Fischer 344 rat.

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12 July 2018

Soluble CD14-mediated cellular responses to lipopolysaccharide

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Mechanisms of intraocular inflammation.

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12 July 2018

NF-kappaB1 (p50) is upregulated in lipopolysaccharide tolerance and can block tumor necrosis factor gene expression

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The Toll-receptor family and control of innate immunity

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Mitogen-activated protein kinase cascades as regulators of stress responses.

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12 July 2018

Effect of macrophage depletion by liposomes containing dichloromethylene-diphosphonate on endotoxin-induced uveitis.

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Retinal dysplasia in mice lacking p56lck.

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12 July 2018

Identification of isoforms of G proteins and PKC that colocalize with tight junctions

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12 July 2018

Intraocular production of a cytokine (CINC) responsible for neutrophil infiltration in endotoxin induced uveitis

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12 July 2018

A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation

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12 July 2018

The role of nitric oxide in uveitis.

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12 July 2018

Kinetics of intraocular tumor necrosis factor and interleukin-6 in endotoxin-induced uveitis in the rat.

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12 July 2018

Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses

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12 July 2018

Expression of multiple cytokines and IL-1RA in the uvea and retina during endotoxin-induced uveitis in the rat.

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12 July 2018

Regulated assembly of tight junctions by protein kinase C.

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12 July 2018

Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

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12 July 2018

Low mature TGF-beta 2 levels in aqueous humor during uveitis.

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12 July 2018

Endotoxin-induced uveitis in rats as a model for human disease

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CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

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Endotoxin-induced uveitis in the rat. The significance of intraocular interleukin-6

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Retino-choroidal changes in endotoxin-induced uveitis in the rat

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Suppressive effects of astaxanthin against rat endotoxin-induced uveitis by inhibiting the NF-kappaB signaling pathway

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Transcriptional profiling reveals complex regulation of the monocyte IL-1 beta system by IL-13.

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PKC-zeta is essential for endotoxin-induced macrophage activation.

1 reference

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Expression of toll-like receptor 4 and its associated lipopolysaccharide receptor complex by resident antigen-presenting cells in the human uvea.

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PKC zeta participates in activation of inflammatory response induced by enteropathogenic E. coli

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Contribution of TNF-α to Leukocyte Adhesion, Vascular Leakage, and Apoptotic Cell Death in Endotoxin-Induced Uveitis In Vivo

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Retinal microenvironment controls resident and infiltrating macrophage function during uveoretinitis.

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25 September 2018

The effects of intraocular injection of interleukin-13 on endotoxin-induced uveitis in rats.

1 reference

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25 September 2018

Delayed onset and decreased severity of experimental autoimmune uveoretinitis in mice lacking nitric oxide synthase type 2.

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25 September 2018

Inhibition of endotoxin-induced uveitis and potentiation of local TNF-alpha and interleukin-6 mRNA expression by interleukin-13.

1 reference

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25 September 2018

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25 September 2018

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25 September 2018

Cytokine mRNA levels in rat ocular tissues after systemic endotoxin treatment.

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25 September 2018

Nitric oxide synthase activity and expression in retinal capillary endothelial cells and pericytes.

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25 September 2018

Endotoxin-induced uveitis in the rat is attenuated by inhibition of nitric oxide production.

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Differential tumor necrosis factor expression by resident retinal cells from experimental uveitis-susceptible and -resistant rat strains

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https://pubmed.ncbi.nlm.nih.gov/17392164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased nitric oxide production in endotoxin-induced uveitis. Reduction of uveitis by an inhibitor of nitric oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17392164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17392164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptors control activation of adaptive immune responses

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https://pubmed.ncbi.nlm.nih.gov/17392164

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based on heuristic

inferred from PubMed ID database lookup

Initial cytokine exposure determines function of macrophages and renders them unresponsive to other cytokines

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-13 suppresses TNF-induced activation of nuclear factor-kappa B, activation protein-1, and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17392164

12 December 2020

based on heuristic

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Cytokines and apoptotic molecules in experimental melanin-protein induced uveitis (EMIU) and experimental autoimmune uveoretinitis (EAU)

1 reference

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based on heuristic

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A role for NF-kappa B subunits p50 and p65 in the inhibition of lipopolysaccharide-induced shock

1 reference

https://pubmed.ncbi.nlm.nih.gov/17392164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An evaluation of ocular inflammation following the injection of bacterial endotoxin into the rat foot pad

1 reference

https://pubmed.ncbi.nlm.nih.gov/17392164

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction and regulation of nitric oxide synthase in retinal Müller glial cells

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2007.060236

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Europe PubMed Central

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28 December 2019

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Europe PubMed Central

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28 December 2019

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Europe PubMed Central

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28 December 2019

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