Actin depletion initiates events leading to granule secretion at the immunological synapse (Q35662889)

9 August 2017

Actin depletion initiates events leading to granule secretion at the immunological synapse (English)

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9 August 2017

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13

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Jennifer Lippincott-Schwartz

9 August 2017

12

object named as

Jennifer Lippincott-Schwartz

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Bi-Chang Chen

object named as

Bi-Chang Chen

5

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Eric Betzig

11

object named as

Eric Betzig

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9 August 2017

3

Jane C Stinchcombe

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9 August 2017

Alex T Ritter

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9 August 2017

Yukako Asano

2

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9 August 2017

N M G Dieckmann

4

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9 August 2017

C Gawden-Bone

6

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9 August 2017

Schuyler van Engelenburg

7

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9 August 2017

Wesley Legant

8

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9 August 2017

Liang Gao

9

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9 August 2017

Michael W Davidson

10

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9 August 2017

language of work or name

English

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publication date

1 May 2015

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9 August 2017

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9 August 2017

42

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5

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9 August 2017

864-876

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describes a project that uses

9 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4448150/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution

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Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL

12 July 2018

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Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse

12 July 2018

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From lipid second messengers to molecular motors: microtubule-organizing center reorientation in T cells

12 July 2018

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Regulated vesicle fusion generates signaling nanoterritories that control T cell activation at the immunological synapse.

12 July 2018

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Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens

12 July 2018

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Coordinated oscillations in cortical actin and Ca2+ correlate with cycles of vesicle secretion

12 July 2018

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Multiple roles for the actin cytoskeleton during regulated exocytosis

12 July 2018

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Integration of the movement of signaling microclusters with cellular motility in immunological synapses.

12 July 2018

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F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation

12 July 2018

1 reference

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Actin retrograde flow and actomyosin II arc contraction drive receptor cluster dynamics at the immunological synapse in Jurkat T cells

12 July 2018

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Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy

12 July 2018

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Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse

12 July 2018

1 reference

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A role for actin arcs in the leading-edge advance of migrating cells

12 July 2018

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Imaging techniques for assaying lymphocyte activation in action

12 July 2018

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Imaging T-cell receptor activation reveals accumulation of tyrosine-phosphorylated CD3ζ in the endosomal compartment.

12 July 2018

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Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain

12 July 2018

1 reference

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The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse

12 July 2018

1 reference

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T cell antigen receptor signaling and immunological synapse stability require myosin IIA

12 July 2018

1 reference

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Lifeact: a versatile marker to visualize F-actin

12 July 2018

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Mechanisms for segregating T cell receptor and adhesion molecules during immunological synapse formation in Jurkat T cells

12 July 2018

1 reference

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Lamellipodial actin mechanically links myosin activity with adhesion-site formation

12 July 2018

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Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation

12 July 2018

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

12 July 2018

1 reference

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A dynamic view of the immunological synapse

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448150

Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

12 July 2018

1 reference

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Cytoskeletal regulation: rich in lipids

12 July 2018

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Real-time visualization of the cytoskeleton and effector functions in T cells.

12 July 2018

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Staging and resetting T cell activation in SMACs

12 July 2018

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Fas ligand is targeted to secretory lysosomes via a proline-rich domain in its cytoplasmic tail.

12 July 2018

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The PACT domain, a conserved centrosomal targeting motif in the coiled-coil proteins AKAP450 and pericentrin.

12 July 2018

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Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis

12 July 2018

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Surpassing the lateral resolution limit by a factor of two using structured illumination microscopy

12 July 2018

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Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion

12 July 2018

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Three-dimensional segregation of supramolecular activation clusters in T cells

12 July 2018

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Centrosome polarization delivers secretory granules to the immunological synapse.

12 July 2018

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Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse; involvement of SNARE complexes.

25 September 2018

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Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448150

The immunological synapse of CTL contains a secretory domain and membrane bridges.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448150

Dynamic actin polymerization drives T cell receptor-induced spreading: a role for the signal transduction adaptor LAT.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448150

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448150

Dynein-Driven Transport of T Cell Receptor Microclusters Regulates Immune Synapse Formation and T Cell Activation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448150

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

7 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448150

Lymphocyte signaling converges on microtubules

7 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25992860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reorientation and fusion of cytotoxic T lymphocyte granules after interaction with target cells as determined by high resolution cinemicrography

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25992860

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.IMMUNI.2015.04.013

1 reference

9 August 2017

1 reference

9 August 2017

1 reference