Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma (Q35627068)

9 August 2017

Loss of Trop2 promotes carcinogenesis and features of epithelial to mesenchymal transition in squamous cell carcinoma (English)

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9 August 2017

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Jianbo Wang

1

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9 August 2017

Kaihua Zhang

2

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9 August 2017

Dorota Grabowska

3

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9 August 2017

Aimin Li

4

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9 August 2017

Yiyu Dong

5

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9 August 2017

Ryan Day

6

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9 August 2017

Peter Humphrey

7

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9 August 2017

James Lewis

8

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9 August 2017

Raleigh D Kladney

9

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9 August 2017

Jeffrey M Arbeit

10

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9 August 2017

Jason D Weber

11

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9 August 2017

Christine H Chung

12

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9 August 2017

Loren S Michel

13

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9 August 2017

4 October 2011

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Molecular Cancer Research

9 August 2017

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9 August 2017

9

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9 August 2017

1686-1695

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9 August 2017

12

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describes a project that uses

9 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3243826/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Suppression of lung adenocarcinoma progression by Nkx2-1

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Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody

12 July 2018

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Trop2 expression contributes to tumor pathogenesis by activating the ERK MAPK pathway.

12 July 2018

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Identification of a cell of origin for human prostate cancer

12 July 2018

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Ranpirnase (frog RNase) targeted with a humanized, internalizing, anti-Trop-2 antibody has potent cytotoxicity against diverse epithelial cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy

12 July 2018

1 reference

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Spindle cell lesions--neoplastic or non-neoplastic?: spindle cell carcinoma and other atypical spindle cell lesions of the head and neck

12 July 2018

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Abnormal placental development and early embryonic lethality in EpCAM-null mice

12 July 2018

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Integrins in cancer: biological implications and therapeutic opportunities

12 July 2018

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Epithelial-mesenchymal transitions in development and disease

12 July 2018

1 reference

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Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

12 July 2018

1 reference

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Trop2: a possible therapeutic target for late stage epithelial carcinomas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

The basics of epithelial-mesenchymal transition

12 July 2018

1 reference

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Nuclear signalling by tumour-associated antigen EpCAM

12 July 2018

1 reference

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Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics

12 July 2018

1 reference

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A novel Src kinase inhibitor reduces tumour formation in a skin carcinogenesis model

12 July 2018

1 reference

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Variant HNF1 modulates epithelial plasticity of normal and transformed ovary cells.

12 July 2018

1 reference

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Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Identification of Trop-2 as an oncogene and an attractive therapeutic target in colon cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinoma

12 July 2018

1 reference

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Identification of conserved gene expression features between murine mammary carcinoma models and human breast tumors

12 July 2018

1 reference

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Clinical significance of TROP2 expression in colorectal cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Serological identification of TROP2 by recombinant cDNA expression cloning using sera of patients with esophageal squamous cell carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

c-Src and cooperating partners in human cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Discovery of novel tumor markers of pancreatic cancer using global gene expression technology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Identification of the gene responsible for gelatinous drop-like corneal dystrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Gene expression profiles in normal and cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Phenotypic investigation of cell junction-related proteins in gelatinous drop-like corneal dystrophy.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear factor-kappaB signaling as characteristics of a high-risk head and neck squamous cell carcinoma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Baseline gene expression predicts sensitivity to gefitinib in non-small cell lung cancer cell lines.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Src and FAK signalling controls adhesion fate and the epithelial-to-mesenchymal transition

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Identification of FGF10 targets in the embryonic lung epithelium during bud morphogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Immunohistochemical p53 expression patterns in sarcomatoid carcinomas of the upper respiratory tract.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Tumor spectrum in ARF-deficient mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

p53 gene dosage modifies growth and malignant progression of keratinocytes expressing the v-rasHa oncogene.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

TROP2 expression as prognostic marker for gastric carcinoma

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

TROP2: a novel prognostic marker in squamous cell carcinoma of the oral cavity

7 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243826

Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression

7 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21970857

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1541-7786.MCR-11-0241

1 reference

9 August 2017

1 reference

9 August 2017

1 reference