Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake (Q35626125)

9 August 2017

title

Discovery of bisamide-heterocycles as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake (English)

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9 August 2017

14

Stuart L Schreiber

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9 August 2017

Chris Dockendorff

1

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9 August 2017

Patrick W Faloon

2

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9 August 2017

Andrew Germain

3

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9 August 2017

Miao Yu

4

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9 August 2017

Willmen Youngsaye

5

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9 August 2017

Partha P Nag

6

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9 August 2017

Melissa Bennion

7

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9 August 2017

Marsha Penman

8

1 reference

9 August 2017

Thomas J F Nieland

9

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9 August 2017

Sivaraman Dandapani

10

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9 August 2017

José R Perez

11

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9 August 2017

Benito Munoz

12

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9 August 2017

Michelle A Palmer

13

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9 August 2017

Monty Krieger

15

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9 August 2017

language of work or name

English

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publication date

11 April 2015

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Bioorganic & Medicinal Chemistry Letters

9 August 2017

number of pages

5

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based on heuristic

inferred from page(s)

published in

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9 August 2017

volume

25

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9 August 2017

issue

12

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9 August 2017

page(s)

2594-2598

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Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport

9 August 2017

cites work

1 reference

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Benzo-fused lactams from a diversity-oriented synthesis (DOS) library as inhibitors of scavenger receptor BI (SR-BI)-mediated lipid uptake

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36

12 July 2018

1 reference

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Safety and antiviral activity of the HCV entry inhibitor ITX5061 in treatment-naive HCV-infected adults: a randomized, double-blind, phase 1b study

12 July 2018

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Discovery of ITX 4520: a highly potent orally bioavailable hepatitis C virus entry inhibitor

12 July 2018

1 reference

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Targeting HCV entry for development of therapeutics

12 July 2018

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Discovery of highly potent small molecule Hepatitis C Virus entry inhibitors

12 July 2018

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Exoplasmic cysteine Cys384 of the HDL receptor SR-BI is critical for its sensitivity to a small-molecule inhibitor and normal lipid transport activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Extracellular disulfide bonds support scavenger receptor class B type I-mediated cholesterol transport

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Glycine dimerization motif in the N-terminal transmembrane domain of the high density lipoprotein receptor SR-BI required for normal receptor oligomerization and lipid transport

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Scavenger receptor class B, type I: a promising immunotherapy target.

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Small molecule scavenger receptor BI antagonists are potent HCV entry inhibitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Mechanism and regulatory function of CpG signaling via scavenger receptor B1 in primary B cells

12 July 2018

1 reference

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Scavenger Receptor BI Protects against Septic Death through Its Role in Modulating Inflammatory Response

12 July 2018

1 reference

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High-Avidity Monoclonal Antibodies against the Human Scavenger Class B Type I Receptor Efficiently Block Hepatitis C Virus Infection in the Presence of High-Density Lipoprotein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Blockade of scavenger receptor class B type I raises high density lipoprotein cholesterol levels but exacerbates atherosclerotic lesion formation in apolipoprotein E deficient mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Recent developments in isocyanide based multicomponent reactions in applied chemistry

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

High density lipoproteins facilitate hepatitis C virus entry through the scavenger receptor class B type I.

12 July 2018

1 reference

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The role of the high-density lipoprotein receptor SR-BI in the lipid metabolism of endocrine and other tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Biological evaluation of 1-alkyl-3-phenylthioureas as orally active HDL-elevating agents

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

Endocytosis is not required for the selective lipid uptake mediated by murine SR-BI.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469081

The use of the Ugi four-component condensation

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25958245

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25958245

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BMCL.2015.03.074

1 reference

9 August 2017

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9 August 2017

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