Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor. (Q37439803)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19815817%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor (English)

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9 February 2020

1

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9 February 2020

author name string

Masahiro Koseki

2

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9 February 2020

Minako Ishibashi

3

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9 February 2020

Christopher J Larson

4

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9 February 2020

Stephen G Miller

5

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9 February 2020

Bernard D King

6

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9 February 2020

Alan R Tall

7

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9 February 2020

language of work or name

English

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publication date

8 October 2009

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Arteriosclerosis, Thrombosis, and Vascular Biology

9 February 2020

published in

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9 February 2020

volume

29

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9 February 2020

issue

12

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9 February 2020

page(s)

2054-2060

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Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice

9 February 2020

cites work

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Identification of the molecular target of small molecule inhibitors of HDL receptor SR-BI activity

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23 August 2017

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Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues

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Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo

23 August 2017

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HDL as a target in the treatment of atherosclerotic cardiovascular disease

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23 August 2017

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Discovery of chemical inhibitors of the selective transfer of lipids mediated by the HDL receptor SR-BI.

23 August 2017

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Influence of the high density lipoprotein receptor SR-BI on reproductive and cardiovascular pathophysiology

23 August 2017

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Targeted mutation reveals a central role for SR-BI in hepatic selective uptake of high density lipoprotein cholesterol

23 August 2017

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CLA-1 is an 85-kD plasma membrane glycoprotein that acts as a high-affinity receptor for both native (HDL, LDL, and VLDL) and modified (OxLDL and AcLDL) lipoproteins

23 August 2017

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A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

23 August 2017

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Identification of scavenger receptor SR-BI as a high density lipoprotein receptor

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Expression of human apolipoprotein A-I in transgenic mice results in reduced plasma levels of murine apolipoprotein A-I and the appearance of two new high density lipoprotein size subclasses

23 August 2017

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Blockade of scavenger receptor class B type I raises high density lipoprotein cholesterol levels but exacerbates atherosclerotic lesion formation in apolipoprotein E deficient mice

23 August 2017

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A novel compound, R-138329, increases plasma HDL cholesterol via inhibition of scavenger receptor BI-mediated selective lipid uptake

14 September 2017

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Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics

14 September 2017

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2 September 2018

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2 September 2018

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2 September 2018

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2 September 2018

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Gene transfer and hepatic overexpression of the HDL receptor SR-BI reduces atherosclerosis in the cholesterol-fed LDL receptor-deficient mouse

2 September 2018

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Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression.

2 September 2018

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Increased LDL cholesterol and atherosclerosis in LDL receptor-deficient mice with attenuated expression of scavenger receptor B1

2 September 2018

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12 December 2020

Variation in susceptibility to atherosclerosis among inbred strains of mice

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12 December 2020

Decreased atherosclerosis in heterozygous low density lipoprotein receptor-deficient mice expressing the scavenger receptor BI transgene

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12 December 2020

Association of polymorphisms at the SR-BI gene locus with plasma lipid levels and body mass index in a white population

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12 December 2020

Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI

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12 December 2020

Expression of cholesteryl ester transfer protein in mice promotes macrophage reverse cholesterol transport

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12 December 2020

p38 MAPK inhibition reduces aortic ultrasmall superparamagnetic iron oxide uptake in a mouse model of atherosclerosis: MRI assessment

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12 December 2020

10.1161/ATVBAHA.109.191320

Identifiers

DOI

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9 February 2020

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9 February 2020

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