Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3. (Q35596910)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775228%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Tau assembly: the dominant role of PHF6 (VQIVYK) in microtubule binding region repeat R3 (English)

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3 March 2020

1

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3 March 2020

Thanh D Do

2

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3 March 2020

Luca Larini

3

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9

Joan-Emma Shea

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3 March 2020

author name string

Nichole E LaPointe

4

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3 March 2020

Alexander J Sercel

5

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3 March 2020

Madeleine F Shade

6

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Stuart C Feinstein

7

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3 March 2020

Michael T Bowers

8

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3 March 2020

language of work or name

English

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publication date

24 March 2015

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Journal of Physical Chemistry B

3 March 2020

published in

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3 March 2020

volume

119

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issue

13

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page(s)

4582-4593

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GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

3 March 2020

cites work

1 reference

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Structural Insight into Tau Protein's Paradox of Intrinsically Disordered Behavior, Self-Acetylation Activity, and Aggregation

12 July 2018

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Single mutations in tau modulate the populations of fibril conformers through seed selection

12 July 2018

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TOC1: characterization of a selective oligomeric tau antibody

12 July 2018

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Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study.

12 July 2018

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Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons

12 July 2018

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Tau oligomers impair artificial membrane integrity and cellular viability

12 July 2018

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Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

12 July 2018

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Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau.

12 July 2018

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Tau isoform composition influences rate and extent of filament formation

12 July 2018

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Trans-cellular propagation of Tau aggregation by fibrillar species

12 July 2018

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Cross-seeding and conformational selection between three- and four-repeat human Tau proteins

12 July 2018

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Identification of oligomers at early stages of tau aggregation in Alzheimer's disease

12 July 2018

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Secondary nucleating sequences affect kinetics and thermodynamics of tau aggregation

12 July 2018

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Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease.

12 July 2018

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Ion mobility-mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation

12 July 2018

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Preparation and characterization of neurotoxic tau oligomers

12 July 2018

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Microtubule assembly, organization and dynamics in axons and dendrites

12 July 2018

1 reference

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Propagation of tau misfolding from the outside to the inside of a cell.

12 July 2018

1 reference

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Formation and growth of oligomers: a Monte Carlo study of an amyloid tau fragment

12 July 2018

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Tau exon 10 alternative splicing and tauopathies

12 July 2018

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A soluble oligomer of tau associated with fiber formation analyzed by NMR.

12 July 2018

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Atomic structures of amyloid cross-beta spines reveal varied steric zippers

12 July 2018

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Mutations causing neurodegenerative tauopathies

12 July 2018

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Tau, tangles, and Alzheimer's disease

12 July 2018

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Tau aggregation is driven by a transition from random coil to beta sheet structure

12 July 2018

1 reference

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Template-assisted filament growth by parallel stacking of tau.

12 July 2018

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The formation of straight and twisted filaments from short tau peptides

12 July 2018

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Rationally designed mutations convert de novo amyloid-like fibrils into monomeric beta-sheet proteins

12 July 2018

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Regulation of alternative splicing of human tau exon 10 by phosphorylation of splicing factors

12 July 2018

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Structural insights into microtubule function

12 July 2018

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Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif ((306)VQIVYK(311)) forming beta structure

12 July 2018

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Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17

12 July 2018

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Canonical dynamics: Equilibrium phase-space distributions

12 July 2018

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Microtubule polymerization dynamics

12 July 2018

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Frequency of stages of Alzheimer-related lesions in different age categories

12 July 2018

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Molecular characterization of the minimal protease resistant tau unit of the Alzheimer's disease paired helical filament

12 July 2018

1 reference

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The microtubule binding domain of tau protein.

12 July 2018

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Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles.

12 July 2018

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Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428543

Effects of pH and charge state on peptide assembly: the YVIFL model system.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428543

β-Sheet core of tau paired helical filaments revealed by solid-state NMR.

26 September 2018

1 reference

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Interplay between I308 and Y310 residues in the third repeat of microtubule-binding domain is essential for tau filament formation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428543

A temperature predictor for parallel tempering simulations.

26 September 2018

1 reference

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Side chain-dependent stacking modulates tau filament structure

26 September 2018

1 reference

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The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis.

26 September 2018

1 reference

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Duplex formation and the onset of helicity in poly d(CG)n oligonucleotides in a solvent-free environment

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428543

Mutations of tau protein in frontotemporal dementia promote aggregation of paired helical filaments by enhancing local beta-structure

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25775228

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of two VQIXXK motifs for tau fibrillization in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25775228

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/ACS.JPCB.5B00175

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775228%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25775228%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference