Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects (Q35560440)

8 August 2017

Roflumilast attenuates allergen-induced inflammation in mild asthmatic subjects (English)

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8 August 2017

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Paul M O'Byrne

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Louis-Philippe Boulet

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object named as

Louis-Philippe Boulet

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8 August 2017

Gail M Gauvreau

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8 August 2017

Christine Schmid-Wirlitsch

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Johanne Côté

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8 August 2017

Mylinh Duong

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8 August 2017

Kieran J Killian

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Joanne Milot

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8 August 2017

Francine Deschesnes

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8 August 2017

Tara Strinich

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Richard M Watson

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8 August 2017

Dirk Bredenbröker

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26 October 2011

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8 August 2017

140

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https://scigraph.springernature.com/pub.10.1186/1465-9921-12-140

8 August 2017

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cites work

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Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials

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The allergen bronchoprovocation model: an important tool for the investigation of new asthma anti-inflammatory therapies

12 July 2018

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12 July 2018

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Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD

12 July 2018

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Differential expression and function of phosphodiesterase 4 (PDE4) subtypes in human primary CD4+ T cells: predominant role of PDE4D

12 July 2018

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Bronchial mucosal inflammation and upregulation of CXC chemoattractants and receptors in severe exacerbations of asthma

12 July 2018

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Type 4A cAMP-specific phosphodiesterase is stored in granules of human neutrophils and eosinophils

12 July 2018

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12 July 2018

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The effect of a novel orally active selective PDE4 isoenzyme inhibitor (CDP840) on allergen-induced responses in asthmatic subjects

12 July 2018

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12 July 2018

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Late asthmatic responses

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Effects of steroid therapy on inflammatory cell subtypes in asthma

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Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials

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Differences in airway cytokine profile in severe asthma compared to moderate asthma.

26 September 2018

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Roflumilast, an oral, once-daily phosphodiesterase 4 inhibitor, attenuates allergen-induced asthmatic reactions

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219708

Increase in airway neutrophils after oral but not inhaled corticosteroid therapy in mild asthma

26 September 2018

1 reference

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Does a single dose of the phosphodiesterase 4 inhibitor, cilomilast (15 mg), induce bronchodilation in patients with chronic obstructive pulmonary disease?

26 September 2018

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Anti-inflammatory and immunomodulatory potential of the novel PDE4 inhibitor roflumilast in vitro.

26 September 2018

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Increased numbers of both airway basophils and mast cells in sputum after allergen inhalation challenge of atopic asthmatics.

26 September 2018

1 reference

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Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects.

26 September 2018

1 reference

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Kinetics of allergen-induced airway eosinophilic cytokine production and airway inflammation

26 September 2018

1 reference

12 December 2020

Efficacy and safety of roflumilast in the treatment of asthma

1 reference

12 December 2020

Roflumilast, a once-daily oral phosphodiesterase 4 inhibitor, lacks relevant pharmacokinetic interactions with inhaled salbutamol when co-administered in healthy subjects

1 reference

12 December 2020

Roflumilast, a phosphodiesterase 4 inhibitor, reduces airway hyperresponsiveness after allergen challenge

1 reference

12 December 2020

Basophil recruitment and IL-4 production during human allergen-induced late asthma

1 reference

12 December 2020

Prediction of airway responsiveness to allergen from skin sensitivity to allergen and airway responsiveness to histamine

1 reference

12 December 2020

Increases in activated T lymphocytes, eosinophils, and cytokine mRNA expression for interleukin-5 and granulocyte/macrophage colony-stimulating factor in bronchial biopsies after allergen inhalation challenge in atopic asthmatics

1 reference

12 December 2020

Allergen-induced recruitment of inflammatory cells in lavage 3 and 24 h after challenge in allergic asthmatic lungs

1 reference

12 December 2020

Effects of allergen challenge on eosinophils, eosinophil cationic protein, and granulocyte-macrophage colony-stimulating factor in mild asthma

1 reference

12 December 2020

Indices of airway inflammation in induced sputum: reproducibility and validity of cell and fluid-phase measurements

1 reference

12 December 2020

Effects of inhaled budesonide on allergen-induced airway responses and airway inflammation

1 reference

12 December 2020

Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD

1 reference

12 December 2020

Identifiers

DOI

10.1186/1465-9921-12-140

1 reference

Dimensions Publication ID

8 August 2017

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1 reference

8 August 2017

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