Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4. (Q35553145)

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28 January 2020

title

Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4 (English)

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28 January 2020

9

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Douglas R Spitz

11

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3

Zita A Sibenaller

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author name string

Kevin P Orcutt

1

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28 January 2020

Arlene D Parsons

2

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28 January 2020

Peter M Scarbrough

4

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Yueming Zhu

5

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28 January 2020

Arya Sobhakumari

6

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28 January 2020

Werner W Wilke

7

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Amanda L Kalen

8

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Francis J Miller

10

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Andrean L Simons

12

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28 January 2020

language of work or name

English

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publication date

11 April 2011

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28 January 2020

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28 January 2020

volume

71

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28 January 2020

issue

11

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28 January 2020

page(s)

3932-3940

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EGFR tyrosine kinase inhibitors and multidrug resistance: perspectives

28 January 2020

cites work

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Inhibition of glutathione and thioredoxin metabolism enhances sensitivity to perifosine in head and neck cancer cells

12 July 2018

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Subcellular localization of Nox4 and regulation in diabetes

12 July 2018

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12 July 2018

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Roles of Nox1 and other Nox isoforms in cancer development

12 July 2018

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Nox4 NADPH oxidase mediates oxidative stress and apoptosis caused by TNF-alpha in cerebral vascular endothelial cells

12 July 2018

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Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production

12 July 2018

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EGFR targeting of solid tumors

12 July 2018

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NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation.

12 July 2018

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Erlotinib, an effective epidermal growth factor receptor tyrosine kinase inhibitor, induces p27KIP1 up-regulation and nuclear translocation in association with cell growth inhibition and G1/S phase arrest in human non-small-cell lung cancer cell lin

12 July 2018

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Cellular responses to EGFR inhibitors and their relevance to cancer therapy

12 July 2018

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Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting

12 July 2018

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The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implications

12 July 2018

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Targeting the epidermal growth factor receptor by erlotinib (Tarceva) for the treatment of esophageal cancer

12 July 2018

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Erlotinib induces cell cycle arrest and apoptosis in hepatocellular cancer cells and enhances chemosensitivity towards cytostatics

12 July 2018

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Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor

12 July 2018

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Protein measurement with the Folin phenol reagent

12 July 2018

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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

12 July 2018

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The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification

12 July 2018

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Persistent oxidative stress in cancer

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 December 2020

Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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12 December 2020

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12 December 2020

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12 December 2020

Overexpression of catalase in cytosolic or mitochondrial compartment protects HepG2 cells against oxidative injury

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12 December 2020

10.1158/0008-5472.CAN-10-3425

Identifiers

DOI

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28 January 2020

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28 January 2020

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