Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry (Q35505448)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22003874%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Haloduracin α binds the peptidoglycan precursor lipid II with 2:1 stoichiometry (English)

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14 January 2020

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Tsung-Shing Andrew Wang

3

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14 January 2020

Wilfred van der Donk

6

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14 January 2020

author name string

Trent J Oman

1

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14 January 2020

Tania J Lupoli

2

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14 January 2020

Daniel Kahne

4

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14 January 2020

Suzanne Walker

5

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14 January 2020

language of work or name

English

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publication date

17 October 2011

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Journal of the American Chemical Society

14 January 2020

published in

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14 January 2020

volume

133

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14 January 2020

issue

44

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14 January 2020

page(s)

17544-17547

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Cinnamycin, an antibiotic from Streptomyces cinnamoneus nov. sp.

14 January 2020

cites work

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Sublancin is not a lantibiotic but an S-linked glycopeptide

27 July 2018

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Lipid II and other bactoprenol-bound cell wall precursors as drug targets.

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Insights into the mode of action of the two-peptide lantibiotic haloduracin

27 July 2018

1 reference

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Structure-activity relationship studies of the two-component lantibiotic haloduracin

27 July 2018

1 reference

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In vitro reconstitution and substrate specificity of a lantibiotic protease.

27 July 2018

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Lipid II as a target for antibiotics

27 July 2018

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Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations

27 July 2018

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Maturation by LctT is required for biosynthesis of full-length lantibiotic lacticin 481.

27 July 2018

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Vancomycin analogues active against vanA-resistant strains inhibit bacterial transglycosylase without binding substrate

27 July 2018

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Two-peptide bacteriocins produced by lactic acid bacteria

27 July 2018

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Complexation of peptidoglycan intermediates by the lipoglycodepsipeptide antibiotic ramoplanin: minimal structural requirements for intermolecular complexation and fibril formation

27 July 2018

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Effect of amino acid substitutions in conserved residues in the leader peptide on biosynthesis of the lantibiotic mutacin II.

27 July 2018

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Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic.

27 July 2018

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The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II.

27 July 2018

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The three-dimensional solution structure of the lantibiotic murein-biosynthesis-inhibitor actagardine determined by NMR

27 July 2018

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Inhibition of peptidoglycan biosynthesis by ramoplanin

27 July 2018

1 reference

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Purification and amino acid sequence of lactocin S, a bacteriocin produced by Lactobacillus sake L45

27 July 2018

1 reference

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Gardimycin, a New Antibiotic Inhibiting Peptidoglycan Synthesis

27 July 2018

1 reference

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Synthesis of the lantibiotic lactocin S using peptide cyclizations on solid phase

27 July 2018

1 reference

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Microtiter plate bioassay to monitor the interference of antibiotics with the lipid II cycle essential for peptidoglycan biosynthesis

26 September 2018

1 reference

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Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206492

Lipid II-based antimicrobial activity of the lantibiotic plantaricin C.

26 September 2018

1 reference

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Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis

26 September 2018

1 reference

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Assembly and stability of nisin-lipid II pores

26 September 2018

1 reference

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Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

26 September 2018

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Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity

26 September 2018

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Ramoplanin inhibits bacterial transglycosylases by binding as a dimer to lipid II.

26 September 2018

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Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

26 September 2018

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Activation of subtilin precursors by Bacillus subtilis extracellular serine proteases subtilisin (AprE), WprA, and Vpr

26 September 2018

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Rethinking ramoplanin: the role of substrate binding in inhibition of peptidoglycan biosynthesis.

26 September 2018

1 reference

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Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics

26 September 2018

1 reference

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Mode of action of the lanthionine-containing peptide antibiotics duramycin, duramycin B and C, and cinnamycin as indirect inhibitors of phospholipase A2

26 September 2018

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12 December 2020

Influence of amino acid substitutions in the nisin leader peptide on biosynthesis and secretion of nisin by Lactococcus lactis

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12 December 2020

The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II

1 reference

12 December 2020

Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125

1 reference

12 December 2020

Identifiers

DOI

10.1021/JA206281K

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22003874%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22003874%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

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