Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma (Q35454927)

8 August 2017

title

Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma (English)

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8 August 2017

9

Leonard Neckers

1 reference

8 August 2017

8

Jane Trepel

1 reference

8 August 2017

4

Bradley Scroggins

1 reference

8 August 2017

3

Kristin Beebe

1 reference

8 August 2017

Hye-Sik Kong

1

1 reference

8 August 2017

Sunmin Lee

2

1 reference

8 August 2017

Gopal Gupta

5

1 reference

8 August 2017

Min-Jung Lee

6

1 reference

8 August 2017

Yun-Jin Jung

7

1 reference

8 August 2017

publication date

2 September 2010

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8 August 2017

published in

Molecular Pharmacology

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8 August 2017

volume

78

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8 August 2017

issue

6

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8 August 2017

page(s)

1072-1078

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HIF-1: upstream and downstream of cancer metabolism

8 August 2017

cites work

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Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors

12 July 2018

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Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells

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Signalling via the hypoxia-inducible factor-1alpha requires multiple posttranslational modifications

12 July 2018

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Berberine inhibits HIF-1alpha expression via enhanced proteolysis

12 July 2018

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The role of von Hippel-Lindau tumor suppressor protein and hypoxia in renal clear cell carcinoma

12 July 2018

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Aryl hydrocarbon nuclear translocator (ARNT) promotes oxygen-independent stabilization of hypoxia-inducible factor-1alpha by modulating an Hsp90-dependent regulatory pathway

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

12 July 2018

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12 July 2018

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NAD(P)H oxidases regulate HIF-2alpha protein expression.

12 July 2018

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Calpain mediates a von Hippel-Lindau protein-independent destruction of hypoxia-inducible factor-1alpha

26 September 2018

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The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma

26 September 2018

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26 September 2018

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

26 September 2018

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Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas

26 September 2018

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26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20813864

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1124/MOL.110.066514

1 reference

8 August 2017

1 reference

8 August 2017

1 reference