Evolution of hepatitis C virus NS5A region in breakthrough patients during pegylated interferon and ribavirin therapy* (Q35293895)

7 August 2017

title

Evolution of hepatitis C virus NS5A region in breakthrough patients during pegylated interferon and ribavirin therapy* (English)

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7 August 2017

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M Gale

4

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author name string

H J Yuan

1

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7 August 2017

M Jain

2

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7 August 2017

K K Snow

3

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7 August 2017

W M Lee

5

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7 August 2017

HALT-C Trial Group

6

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7 August 2017

publication date

28 July 2009

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Journal of Viral Hepatitis

7 August 2017

published in

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7 August 2017

volume

17

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7 August 2017

issue

3

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7 August 2017

page(s)

208-216

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Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon

7 August 2017

cites work

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Comparative Analysis of Nearly Full-Length Hepatitis C Virus Quasispecies from Patients Experiencing Viral Breakthrough during Antiviral Therapy: Clustered Mutations in Three Functional Genes, E2, NS2, and NS5a

12 July 2018

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12 July 2018

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Identification of Residues Required for RNA Replication in Domains II and III of the Hepatitis C Virus NS5A Protein

12 July 2018

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Pretreatment Sequence Diversity Differences in the Full-Length Hepatitis C Virus Open Reading Frame Correlate with Early Response to Therapy

12 July 2018

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Conserved Determinants for Membrane Association of Nonstructural Protein 5A from Hepatitis C Virus and Related Viruses

12 July 2018

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Evasion of intracellular host defence by hepatitis C virus

12 July 2018

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12 July 2018

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Hepatitis C virus NS5A: tales of a promiscuous protein

12 July 2018

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Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes

12 July 2018

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Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose

12 July 2018

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12 July 2018

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Subversion of Cell Signaling Pathways by Hepatitis C Virus Nonstructural 5A Protein via Interaction with Grb2 and P85 Phosphatidylinositol 3-Kinase

12 July 2018

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Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome

12 July 2018

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Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

12 July 2018

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Expression of hepatitis C virus NS5A natural mutants in a hepatocytic cell line inhibits the antiviral effect of interferon in a PKR-independent manner

12 July 2018

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How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A.

12 July 2018

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Prospective characterization of full-length hepatitis C virus NS5A quasispecies during induction and combination antiviral therapy

12 July 2018

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The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies

12 July 2018

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Hepatitis C virus NS5A protein inhibits interferon antiviral activity, but the effects do not correlate with clinical response

12 July 2018

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Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein

12 July 2018

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NS5A, a nonstructural protein of hepatitis C virus, binds growth factor receptor-bound protein 2 adaptor protein in a Src homology 3 domain/ligand-dependent manner and perturbs mitogenic signaling

12 July 2018

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Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation

12 July 2018

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Evolution of hepatitis C virus quasispecies in hypervariable region 1 and the putative interferon sensitivity-determining region during interferon therapy and natural infection.

12 July 2018

1 reference

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Mutations in the nonstructural 5A gene of European hepatitis C virus isolates and response to interferon alfa

12 July 2018

1 reference

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Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

12 July 2018

1 reference

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Sequence analysis of the NS5A protein of European hepatitis C virus 1b isolates and relation to interferon sensitivity.

12 July 2018

1 reference

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The non-structural 5A protein of hepatitis C virus exhibits genotypic differences in interferon antagonism.

21 January 2018

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NS5A sequences of hepatitis C virus genotype 1 and interferon resistance: where are we?

26 September 2018

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Impact of NS5A sequences of Hepatitis C virus genotype 1a on early viral kinetics during treatment with peginterferon- alpha 2a plus ribavirin

26 September 2018

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Impact of reducing peginterferon alfa-2a and ribavirin dose during retreatment in patients with chronic hepatitis C.

26 September 2018

1 reference

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HCV RNA detection by TMA during the hepatitis C antiviral long-term treatment against cirrhosis (Halt-C) trial

26 September 2018

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Evolution of the HALT-C Trial: pegylated interferon as maintenance therapy for chronic hepatitis C in previous interferon nonresponders.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

Genetic variability of hepatitis C virus in chronically infected patients with viral breakthrough during interferon-ribavirin therapy

26 September 2018

1 reference

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Peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

Genetic heterogeneity of the NS5A gene of hepatitis C virus and early response to interferon-alpha

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

Prediction of treatment outcome in patients with chronic hepatitis C: significance of baseline parameters and viral dynamics during therapy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

Adherence to combination therapy enhances sustained response in genotype-1-infected patients with chronic hepatitis C.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

Analysis of sequence configurations of the ISDR, PKR-binding domain, and V3 region as predictors of response to induction interferon-alpha and ribavirin therapy in chronic hepatitis C infection

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

Co-infection by serologically-silent hepatitis B virus may contribute to poor interferon response in patients with chronic hepatitis C by down-regulation of type-I interferon receptor gene expression in the liver

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

Expression of interferon alpha/beta receptor in the liver of chronic hepatitis C patients

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189487

10.1111/J.1365-2893.2009.01169.X

26 September 2018

Identifiers

DOI

1 reference

release_tcyfjpwf55cplfnbl6ooqe6cpu

7 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tcyfjpwf55cplfnbl6ooqe6cpu

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMC publication ID

3189487

1 reference

7 August 2017

1 reference