Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones (Q35242884)

7 August 2017

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones (English)

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7 August 2017

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5

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7 August 2017

Andrew W Norris

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Bruce Spiegelman

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object named as

Bruce M Spiegelman

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7 August 2017

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C Ronald Kahn

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7 August 2017

8

Evan D Rosen

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7 August 2017

Lihong Chen

2

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7 August 2017

Simon J Fisher

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7 August 2017

Ildiko Szanto

4

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7 August 2017

Alison C Jozsi

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7 August 2017

Michael F Hirshman

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7 August 2017

Laurie J Goodyear

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7 August 2017

Frank J Gonzalez

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7 August 2017

language of work or name

English

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publication date

1 August 2003

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Journal of Clinical Investigation

7 August 2017

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7 August 2017

112

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7 August 2017

608-618

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4

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describes a project that uses

7 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC171387/fullTextXML

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Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency

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Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

12 July 2018

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12 July 2018

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Dissociation and enrichment of rat atrial myocytes containing atrial natriuretic factor (ANF).

12 July 2018

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In vitro studies on the action of CS-045, a new antidiabetic agent

12 July 2018

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Evolution of insulin resistance in New Zealand obese mice.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

A Technique for the Combination of Clearing, Staining, and Injecting Small Mammals

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Loss of the peroxisome proliferation-activated receptor gamma (PPARgamma ) does not affect mammary development and propensity for tumor formation but leads to reduced fertility

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Peroxisome proliferator-activated receptor (PPAR) gamma and retinoid X receptor (RXR) agonists have complementary effects on glucose and lipid metabolism in human skeletal muscle

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Prolonged inhibition of muscle carnitine palmitoyltransferase-1 promotes intramyocellular lipid accumulation and insulin resistance in rats

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Plasma FFA utilization and fatty acid-binding protein content are diminished in type 2 diabetic muscle.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Dilated cardiomyopathy and atrioventricular conduction blocks induced by heart-specific inactivation of mitochondrial DNA gene expression.

26 September 2018

1 reference

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Reduced expression of pax-3 is associated with overexpression of cdc46 in the mouse embryo.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

Insulin resistance and insulin secretory dysfunction as precursors of non-insulin-dependent diabetes mellitus. Prospective studies of Pima Indians

26 September 2018

1 reference

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A potent in vivo effect of ciglitazone on muscle insulin resistance induced by high fat feeding of rats

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=171387

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

26 September 2018

1 reference

12 December 2020

Effect of dietary fat content on the incidence of obesity among ad libitum fed mice

1 reference

12 December 2020

Monoamine oxidase activities in dissociated cell fractions from rat skeletal muscle

1 reference

12 December 2020

Myogenicity in vitro and in vivo of mouse muscle cells separated on discontinuous Percoll gradients

1 reference

12 December 2020

Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

1 reference

12 December 2020

A moderate decline in specific activity does not lead to an underestimation of hepatic glucose production during a glucose clamp

1 reference

12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

12 December 2020

Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase

1 reference

12 December 2020

Mechanism of troglitazone action in type 2 diabetes

1 reference

12 December 2020

Expression of genes involved in lipid metabolism correlate with peroxisome proliferator-activated receptor gamma expression in human skeletal muscle

1 reference

12 December 2020

Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise

1 reference

12 December 2020

The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI17305

1 reference

7 August 2017

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7 August 2017

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