The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis (Q24291114)

signal transduction in response to DNA damage

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

5

J Lukas

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Jiří Bártek

4

object named as

J Bartek

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author name string

J Falck

1

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N Mailand

2

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R G Syljuåsen

3

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J Bartek

Cell cycle control and cancer

4

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language of work or name

English

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publication date

12 April 2001

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published in

Nature

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volume

410

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page(s)

842-7

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issue

6830

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cites work

1 reference

Cell cycle checkpoints: preventing an identity crisis

21 January 2018

1 reference

Radiosensitivity in ataxia-telangiectasia: a new explanation

21 January 2018

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ATM: a mediator of multiple responses to genotoxic stress

21 January 2018

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The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

21 January 2018

1 reference

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

21 January 2018

1 reference

Rapid destruction of human Cdc25A in response to DNA damage

21 January 2018

1 reference

Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis

21 January 2018

1 reference

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 January 2018

1 reference

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

21 January 2018

1 reference

Replication checkpoint enforced by kinases Cds1 and Chk1.

21 January 2018

1 reference

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

21 January 2018

1 reference

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

21 January 2018

1 reference

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 January 2018

1 reference

Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint

21 January 2018

1 reference

The FHA domain is a modular phosphopeptide recognition motif.

21 January 2018

1 reference

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

21 January 2018

1 reference

14-3-3Sigma is required to prevent mitotic catastrophe after DNA damage

21 January 2018

1 reference

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 January 2018

1 reference

Requirements for p53 and the ATM gene product in the regulation of G1/S and S phase checkpoints.

21 January 2018

1 reference

CDC25 phosphatases as potential human oncogenes

21 January 2018

1 reference

hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response

21 January 2018

1 reference

Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

21 January 2018

1 reference

Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1

21 January 2018

1 reference

DNA damage and checkpoint pathways: molecular anatomy and interactions with repair

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

1 reference