Modeling the functional genomics of autism using human neurons (Q35207317)

7 August 2017

Modeling the functional genomics of autism using human neurons (English)

1 reference

7 August 2017

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1 reference

G Konopka

1

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author name string

E Wexler

2

1 reference

7 August 2017

E Rosen

3

1 reference

7 August 2017

Z Mukamel

4

1 reference

7 August 2017

G E Osborn

5

1 reference

7 August 2017

L Chen

6

1 reference

7 August 2017

D Lu

7

1 reference

7 August 2017

F Gao

8

1 reference

7 August 2017

K Gao

9

1 reference

7 August 2017

J K Lowe

10

1 reference

7 August 2017

D H Geschwind

11

1 reference

7 August 2017

language of work or name

English

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publication date

7 June 2011

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7 August 2017

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7 August 2017

17

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7 August 2017

202-214

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7 August 2017

2

1 reference

describes a project that uses

7 August 2017

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/3170664

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/mp.2011.60

0 references

cites work

Functional genomics of the brain: uncovering networks in the CNS using a systems approach

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A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells

13 July 2018

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Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2

13 July 2018

1 reference

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Allelic diversity in human developmental neurogenetics: insights into biology and disease

13 July 2018

1 reference

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The psychiatric GWAS consortium: big science comes to psychiatry

13 July 2018

1 reference

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Induced pluripotency: history, mechanisms, and applications

13 July 2018

1 reference

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High-content screening of small compounds on human embryonic stem cells.

13 July 2018

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Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways

13 July 2018

1 reference

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Key role for gene dosage and synaptic homeostasis in autism spectrum disorders

13 July 2018

1 reference

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In the swim of things: recent insights to neurogenetic disorders from zebrafish

13 July 2018

1 reference

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Behavioural phenotyping assays for mouse models of autism

13 July 2018

1 reference

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Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum

13 July 2018

1 reference

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Functional impact of global rare copy number variation in autism spectrum disorders

13 July 2018

1 reference

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A mutation affecting the sodium/proton exchanger, SLC9A6, causes mental retardation with tau deposition

13 July 2018

1 reference

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Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency

13 July 2018

1 reference

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Evolution in health and medicine Sackler colloquium: Comparative genomics of autism and schizophrenia

13 July 2018

1 reference

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Human-specific transcriptional regulation of CNS development genes by FOXP2

13 July 2018

1 reference

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Neuroscience in the era of functional genomics and systems biology

13 July 2018

1 reference

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A genome-wide linkage and association scan reveals novel loci for autism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Autistic spectrum disorders as functional disconnection syndrome.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

A systems genetics approach implicates USF1, FADS3, and other causal candidate genes for familial combined hyperlipidemia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Making cortex in a dish: In vitro corticopoiesis from embryonic stem cells

13 July 2018

1 reference

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

A de novo 1p34.2 microdeletion identifies the synaptic vesicle gene RIMS3 as a novel candidate for autism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disorders

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Genetic advances in autism: heterogeneity and convergence on shared pathways

13 July 2018

1 reference

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Functional and evolutionary insights into human brain development through global transcriptome analysis

13 July 2018

1 reference

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A genome-wide association study of autism reveals a common novel risk locus at 5p14.1

13 July 2018

1 reference

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The Role of Epilepsy and Epileptiform EEGs in Autism Spectrum Disorders

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Endogenous Wnt signaling maintains neural progenitor cell potency

13 July 2018

1 reference

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Autism genome-wide copy number variation reveals ubiquitin and neuronal genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Common genetic variants on 5p14.1 associate with autism spectrum disorders

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Polarized targeting of neurexins to synapses is regulated by their C-terminal sequences

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Copy-number variations associated with neuropsychiatric conditions

13 July 2018

1 reference

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Neuroligins and neurexins link synaptic function to cognitive disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Functional organization of the transcriptome in human brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Molecular genetics of adult ADHD: converging evidence from genome-wide association and extended pedigree linkage studies

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Geometric interpretation of gene coexpression network analysis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Animal models of psychiatric disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Psychosis and autism as diametrical disorders of the social brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Genetic regulation of arealization of the neocortex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Advances in autism genetics: on the threshold of a new neurobiology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Variations in DNA elucidate molecular networks that cause disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Disruption of neurexin 1 associated with autism spectrum disorder

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

The neurobiology of autism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

PLINK: a tool set for whole-genome association and population-based linkage analyses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Bidirectional Eph-ephrin signaling during axon guidance

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Strong association of de novo copy number mutations with autism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Autism spectrum disorders: developmental disconnection syndromes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

A general framework for weighted gene co-expression network analysis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Neuroanatomic observations of the brain in autism: a review and future directions

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Wnt genes define distinct boundaries in the developing human brain: implications for human forebrain patterning

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

The biology of epilepsy genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Semaphorin junction: making tracks toward neural connectivity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Glial cells generate neurons: the role of the transcription factor Pax6.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

A new method for the rapid and long term growth of human neural precursor cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

The ephrins and Eph receptors in neural development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Activation of hepatocyte growth factor by the plasminogen activators uPA and tPA.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Microtubule-associated proteins: a monoclonal antibody to MAP2 binds to differentiated neurons

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Glial fibrillary acidic protein (GFAP): the major protein of glial intermediate filaments in differentiated astrocytes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

The expression and posttranslational modification of a neuron-specific beta-tubulin isotype during chick embryogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

De novo SYNGAP1 mutations in nonsyndromic intellectual disability and autism.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Epilepsy and autism spectrum disorders: are there common developmental mechanisms?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

An integrated genomic analysis of gene-function correlation on schizophrenia susceptibility genes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

The organization of the transcriptional network in specific neuronal classes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Nonprimed and DYRK1A-primed GSK3 beta-phosphorylation sites on MAP1B regulate microtubule dynamics in growing axons.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Semaphorin 5A is a bifunctional axon guidance cue for axial motoneurons in vivo.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Schizophrenia: genome, interrupted.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Neuronal differentiation is accompanied by increased levels of SNAP-25 protein in fetal rat primary cortical neurons: implications in neuronal plasticity and Alzheimer's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Cell culture. Progenitor cells from human brain after death.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170664

Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21647150

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

LNCaP prostatic adenocarcinoma cells derived from low and high passage numbers display divergent responses not only to androgens but also to retinoids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21647150

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MP.2011.60

1 reference

7 August 2017

1 reference

7 August 2017

1 reference