Insights into prion biology: integrating a protein misfolding pathway with its cellular environment (Q35194908)

7 August 2017

1 reference

title

Insights into prion biology: integrating a protein misfolding pathway with its cellular environment (English)

1 reference

7 August 2017

0 references

Susanne DiSalvo

1

1 reference

PubMed ID

21654204

7 August 2017

Tricia R Serio

series ordinal

2

1 reference

7 August 2017

1 April 2011

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7 August 2017

1 reference

7 August 2017

5

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7 August 2017

76-83

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7 August 2017

2

1 reference

The strain-encoded relationship between PrP replication, stability and processing in neurons is predictive of the incubation period of disease

7 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Strain conformation, primary structure and the propagation of the yeast prion [PSI+].

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion propagation and toxicity in vivo occur in two distinct mechanistic phases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The prion hypothesis: from biological anomaly to basic regulatory mechanism

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

A size threshold limits prion transmission and establishes phenotypic diversity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The physical relationship between infectivity and prion protein aggregates is strain-dependent

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Mammalian prions generated from bacterially expressed prion protein in the absence of any mammalian cofactors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Coinfecting prion strains compete for a limiting cellular resource

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion dynamics and the quest for the genetic determinant in protein-only inheritance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Sequestration of essential proteins causes prion associated toxicity in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Investigating the conformational stability of prion strains through a kinetic replication model

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Bridging the gap: from protein misfolding to protein misfolding diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion variants, species barriers, generation and propagation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The cellular concentration of the yeast Ure2p prion protein affects its propagation as a prion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion propagation: the role of protein dynamics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Novel dominant-negative prion protein mutants identified from a randomized library

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Effective gene therapy in a mouse model of prion diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

A general model of prion strains and their pathogenicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Cell division modulates prion accumulation in cultured cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The structural basis of yeast prion strain variants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The dominant-negative effect of the Q218K variant of the prion protein does not require protein X.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Continuum of prion protein structures enciphers a multitude of prion isolate-specified phenotypes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

"Prion-proof" for [PIN+]: infection with in vitro-made amyloid aggregates of Rnq1p-(132-405) induces [PIN+]

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Analysis of amyloid aggregates using agarose gel electrophoresis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion strain-dependent differences in conversion of mutant prion proteins in cell culture

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The most infectious prion protein particles.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Search for a prion-specific nucleic acid

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Strain-specified characteristics of mouse synthetic prions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Hsp70 chaperones as modulators of prion life cycle: novel effects of Ssa and Ssb on the Saccharomyces cerevisiae prion [PSI+]

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Inhibition of PrPSc formation by lentiviral gene transfer of PrP containing dominant negative mutations.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Dissection and design of yeast prions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Conformational variations in an infectious protein determine prion strain differences

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Yeast [PSI+] Prion Aggregates Are Formed by Small Sup35 Polymers Fragmented by Hsp104

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Analysis of the Generation and Segregation of Propagons: Entities That Propagate the [PSI+] Prion in Yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Conservation of the prion properties of Ure2p through evolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Abbreviated incubation times for human prions in mice expressing a chimeric mouse-human prion protein transgene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Dominant-negative inhibition of prion replication in transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Interactions among prions and prion "strains" in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Long-term subclinical carrier state precedes scrapie replication and adaptation in a resistant species: analogies to bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Induction of distinct [URE3] yeast prion strains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Strain-specified relative conformational stability of the scrapie prion protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Interactions between heterologous forms of prion protein: binding, inhibition of conversion, and species barriers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Susceptibility of sheep for scrapie as assessed by in vitro conversion of nine naturally occurring variants of PrP.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

[PSI+]: an epigenetic modulator of translation termination efficiency

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Quantifying the kinetic parameters of prion replication.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion protein and species barriers in the transmissible spongiform encephalopathies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The yeast non-Mendelian factor [ETA+] is a variant of [PSI+], a prion-like form of release factor eRF3.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion domain initiation of amyloid formation in vitro from native Ure2p

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Eight prion strains have PrP(Sc) molecules with different conformations

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Mechanism of inhibition of Psi+ prion determinant propagation by a mutation of the N-terminus of the yeast Sup35 protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

A critical role for amino-terminal glutamine/asparagine repeats in the formation and propagation of a yeast prion

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

28 July 2018

Prion Protein Biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion-inducing domain 2-114 of yeast Sup35 protein transforms in vitro into amyloid-like filaments

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Propagation of the yeast prion-like [psi+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Support for the prion hypothesis for inheritance of a phenotypic trait in yeast

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Mice devoid of PrP are resistant to scrapie

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The dominant PNM2- mutation which eliminates the psi factor of Saccharomyces cerevisiae is the result of a missense mutation in the SUP35 gene.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Transmission of Creutzfeldt-Jakob disease from humans to transgenic mice expressing chimeric human-mouse prion protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Heterologous PrP molecules interfere with accumulation of protease-resistant PrP in scrapie-infected murine neuroblastoma cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Ablation of the prion protein (PrP) gene in mice prevents scrapie and facilitates production of anti-PrP antibodies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Non-genetic propagation of strain-specific properties of scrapie prion protein.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Novel proteinaceous infectious particles cause scrapie

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Some factors controlling the incidence of scrapie in Cheviot sheep injected with a Cheviot-passaged scrapie agent.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Self-replication and scrapie

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Scrapie in mice. Agent-strain differences in the distribution and intensity of grey matter vacuolation.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Genetic aspects of unconventional virus infections: the basis of the virino hypothesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Identification of two biologically distinct strains of transmissible mink encephalopathy in hamsters.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Polymorphisms of a scrapie-associated fibril protein (PrP) gene and their association with susceptibility to experimentally induced scrapie in Cheviot sheep in the United States

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Chimeric prion protein expression in cultured cells and transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Resistance of Scrapie Agent to Decontamination

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Evidence that the Transmission of One Source of Scrapie Agent to Hamsters Involves Separation of Agent Strains from a Mixture

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

[URE3] as an altered URE2 protein: evidence for a prion analog in Saccharomyces cerevisiae

28 July 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Prion generation in vitro: amyloid of Ure2p is infectious

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Protein-only transmission of three yeast prion strains.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Amyloid aggregates of the HET-s prion protein are infectious

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Generating a prion with bacterially expressed recombinant prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Cell-free formation of protease-resistant prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

The HET-s prion protein of the filamentous fungus Podospora anserina aggregates in vitro into amyloid-like fibrils.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Prion protein remodelling confers an immediate phenotypic switch.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Preclinical changes in weight of scrapie-infected mice as a function of scrapie agent-mouse strain combination

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Observations on thermostable subpopulations of the unconventional agents that cause transmissible degenerative encephalopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Human prion protein with valine 129 prevents expression of variant CJD phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Strain-dependent differences in beta-sheet conformations of abnormal prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

A change in the conformation of prions accompanies the emergence of a new prion strain.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

The physical basis of how prion conformations determine strain phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Strain-specific Kinetics of Prion Protein Formation in Vitro and in Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Ψ, A cytoplasmic suppressor of super-suppressor in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

The number and transmission of [PSI] prion seeds (Propagons) in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

The [URE3] prion is an aggregated form of Ure2p that can be cured by overexpression of Ure2p fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Single mother-daughter pair analysis to clarify the diffusion properties of yeast prion Sup35 in guanidine-HCl-treated [PSI] cells

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Guanidine hydrochloride inhibits the generation of prion "seeds" but not prion protein aggregation in yeast.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Size distribution dependence of prion aggregates infectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Prion clearance in bigenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Molecular genetics of prion diseases in France. French Research Group on Epidemiology of Human Spongiform Encephalopathies.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Human prion protein (PrP) 219K is converted to PrPSc but shows heterozygous inhibition in variant Creutzfeldt-Jakob disease infection

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Molecular classification of sporadic Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Intracerebroventricular delivery of dominant negative prion protein in a mouse model of iatrogenic Creutzfeldt-Jakob disease after dura graft transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Designing drugs to stop the formation of prion aggregates and other amyloids.

21 January 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

The shortest known prion protein gene allele occurs in goats, has only three octapeptide repeats and is non-pathogenic.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Termination of translation in eukaryotes is governed by two interacting polypeptide chain release factors, eRF1 and eRF3.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3166505

Scrapie incubation time can exceed natural lifespan

27 September 2018

1 reference

https://api.crossref.org/works/10.4161%2FPRI.5.2.16413

Infectivity versus toxicity

21 January 2018

1 reference

12 December 2020

Rnq1: an epigenetic modifier of protein function in yeast

1 reference

12 December 2020

Host-genotype and agent effects in scrapie incubation: Change in allelic interaction with different strains of agent

1 reference

12 December 2020

Scrapie produced experimentally in goats with special reference to the clinical syndrome

1 reference

12 December 2020

Disinfection studies with two strains of mouse-passaged scrapie agent. Guidelines for Creutzfeldt-Jakob and related agents

1 reference

12 December 2020

The PNM2 mutation in the prion protein domain of SUP35 has distinct effects on different variants of the [PSI+] prion in yeast

1 reference

12 December 2020

Association between natural scrapie and PrP genotype in a flock of Suffolk sheep in Scotland

1 reference

12 December 2020

Temporary and permanent modifications to a single strain of mouse scrapie on transmission to rats and hamsters

1 reference

12 December 2020

Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie

1 reference

12 December 2020

Identifiers

DOI

10.4161/PRI.5.2.16413

1 reference

7 August 2017

1 reference

7 August 2017

1 reference

PubMed ID

21654204